Blaney SMHL, Adamson PC (2021) Pizzo and poplack’s pediatric oncology. Williams and Wilkins, Lippincott
Pajtler KW, Witt H, Sill M, Jones DT, Hovestadt V, Kratochwil F et al (2015) Molecular classification of ependymal tumors across All CNS compartments, histopathological grades, and age groups. Cancer Cell 27(5):728–743
Article PubMed PubMed Central CAS Google Scholar
Zschernack V, Junger ST, Mynarek M, Rutkowski S, Garre ML, Ebinger M et al (2021) Supratentorial ependymoma in childhood: more than just RELA or YAP. Acta Neuropathol 141(3):455–466
Article PubMed PubMed Central CAS Google Scholar
Louis DN, Perry A, Wesseling P, Brat DJ, Cree IA, Figarella-Branger D et al (2021) The 2021 WHO classification of tumors of the central nervous system: a summary. Neuro Oncol 23(8):1231–1251
Article PubMed PubMed Central CAS Google Scholar
Louis DN, Perry A, Reifenberger G, von Deimling A, Figarella-Branger D, Cavenee WK et al (2016) The 2016 world health organization classification of tumors of the central nervous system: a summary. Acta Neuropathol 131(6):803–820
Merchant TE (2017) Current clinical challenges in childhood ependymoma: a focused review. J Clin Oncol 35(21):2364–2369
Ellison DW, Kocak M, Figarella-Branger D, Felice G, Catherine G, Pietsch T et al (2011) Histopathological grading of pediatric ependymoma: reproducibility and clinical relevance in European trial cohorts. J Negat Results Biomed 10:7
Article PubMed PubMed Central Google Scholar
Kresbach C, Neyazi S, Schuller U (2022) Updates in the classification of ependymal neoplasms: the 2021 WHO Classification and beyond. Brain Pathol 32(4):e13068
Article PubMed PubMed Central Google Scholar
Ellison DW, Aldape KD, Capper D, Fouladi M, Gilbert MR, Gilbertson RJ et al (2020) cIMPACT-NOW update 7: advancing the molecular classification of ependymal tumors. Brain Pathol 30(5):863–866
Article PubMed PubMed Central Google Scholar
Capper D, Jones DTW, Sill M, Hovestadt V, Schrimpf D, Sturm D et al (2018) DNA methylation-based classification of central nervous system tumours. Nature 555(7697):469–474
Article PubMed PubMed Central CAS Google Scholar
Panwalkar P, Clark J, Ramaswamy V, Hawes D, Yang F, Dunham C et al (2017) Immunohistochemical analysis of H3K27me3 demonstrates global reduction in group—a childhood posterior fossa ependymoma and is a powerful predictor of outcome. Acta Neuropathol 134(5):705–714
Article PubMed PubMed Central CAS Google Scholar
Palma L, Celli P, Mariottini A, Zalaffi A, Schettini G (2000) The importance of surgery in supratentorial ependymomas: long-term survival in a series of 23 cases. Childs Nerv Syst 16(3):170–175
Article PubMed CAS Google Scholar
Hukin J, Epstein F, Lefton D, Allen J (1998) Treatment of intracranial ependymoma by surgery alone. Pediatr Neurosurg 29(1):40–45
Article PubMed CAS Google Scholar
Merchant TE, Li C, Xiong X, Kun LE, Boop FA, Sanford RA (2009) Conformal radiotherapy after surgery for paediatric ependymoma: a prospective study. Lancet Oncol 10(3):258–266
Article PubMed PubMed Central Google Scholar
Merchant TE, Bendel AE, Sabin ND, Burger PC, Shaw DW, Chang E et al (2019) Conformal radiation therapy for pediatric ependymoma, chemotherapy for incompletely resected ependymoma, and observation for completely resected. Supratentorial Ependymoma J Clin Oncol 37(12):974–983
Article PubMed CAS Google Scholar
Parker M, Mohankumar KM, Punchihewa C, Weinlich R, Dalton JD, Li Y et al (2014) C11orf95-RELA fusions drive oncogenic NF-kappaB signalling in ependymoma. Nature 506(7489):451–455
Article PubMed PubMed Central CAS Google Scholar
Modena P, Lualdi E, Facchinetti F, Veltman J, Reid JF, Minardi S et al (2006) Identification of tumor-specific molecular signatures in intracranial ependymoma and association with clinical characteristics. J Clin Oncol 24(33):5223–5233
Article PubMed CAS Google Scholar
Witt H, Mack SC, Ryzhova M, Bender S, Sill M, Isserlin R et al (2011) Delineation of two clinically and molecularly distinct subgroups of posterior fossa ependymoma. Cancer Cell 20(2):143–157
Article PubMed PubMed Central CAS Google Scholar
Taylor MD, Poppleton H, Fuller C, Su X, Liu Y, Jensen P et al (2005) Radial glia cells are candidate stem cells of ependymoma. Cancer Cell 8(4):323–335
Article PubMed CAS Google Scholar
Puget S, Grill J, Valent A, Bieche I, Dantas-Barbosa C, Kauffmann A et al (2009) Candidate genes on chromosome 9q33-34 involved in the progression of childhood ependymomas. J Clin Oncol 27(11):1884–1892
Article PubMed CAS Google Scholar
Johnson RA, Wright KD, Poppleton H, Mohankumar KM, Finkelstein D, Pounds SB et al (2010) Cross-species genomics matches driver mutations and cell compartments to model ependymoma. Nature 466(7306):632–636
Article PubMed PubMed Central CAS Google Scholar
Mack SC, Witt H, Piro RM, Gu L, Zuyderduyn S, Stutz AM et al (2014) Epigenomic alterations define lethal CIMP-positive ependymomas of infancy. Nature 506(7489):445–450
Article PubMed PubMed Central CAS Google Scholar
Gubbiotti MA, Madsen PJ, Tucker AM, Abdullaev Z, Aldape K, Shekdar K et al (2023) ZFTA-fused supratentorial ependymoma with a novel fusion partner, DUX4. J Neuropathol Exp Neurol 82(7):668–671
Article PubMed PubMed Central Google Scholar
Pietsch T, Wohlers I, Goschzik T, Dreschmann V, Denkhaus D, Dorner E et al (2014) Supratentorial ependymomas of childhood carry C11orf95-RELA fusions leading to pathological activation of the NF-kappaB signaling pathway. Acta Neuropathol 127(4):609–611
Zheng T, Ghasemi DR, Okonechnikov K, Korshunov A, Sill M, Maass KK et al (2021) Cross-species genomics reveals oncogenic dependencies in ZFTA/C11orf95 fusion-positive supratentorial ependymomas. Cancer Discov 11(9):2230–2247
Article PubMed CAS Google Scholar
Kupp R, Ruff L, Terranova S, Nathan E, Ballereau S, Stark R et al (2021) ZFTA translocations constitute ependymoma chromatin remodeling and transcription factors. Cancer Discov 11(9):2216–2229
Article PubMed PubMed Central CAS Google Scholar
Arabzade A, Zhao Y, Varadharajan S, Chen HC, Jessa S, Rivas B et al (2021) ZFTA-RELA dictates oncogenic transcriptional programs to drive aggressive supratentorial ependymoma. Cancer Discov 11(9):2200–2215
Article PubMed PubMed Central CAS Google Scholar
Tauziede-Espariat A, Nicaise Y, Sievers P, Sahm F, von Deimling A, Guillemot D et al (2024) CNS tumors with PLAGL1-fusion: beyond ZFTA and YAP1 in the genetic spectrum of supratentorial ependymomas. Acta Neuropathol Commun 12(1):55
Article PubMed PubMed Central CAS Google Scholar
Tauziede-Espariat A, Siegfried A, Nicaise Y, Kergrohen T, Sievers P, Vasiljevic A et al (2021) Supratentorial non-RELA, ZFTA-fused ependymomas: a comprehensive phenotype genotype correlation highlighting the number of zinc fingers in ZFTA-NCOA1/2 fusions. Acta Neuropathol Commun 9(1):135
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