Siegel RL, Miller KD, Fuchs HE, Jemal A. Cancer statistics, 2022. CA Cancer J Clin. 2022;72(1):7–33. https://doi.org/10.3322/caac.21708.
Rosenberg SA, Tepper J, Glatstein E, et al. The treatment of soft-tissue sarcomas of the extremities: prospective randomized evaluations of (1) limb-sparing surgery plus radiation therapy compared with amputation and (2) the role of adjuvant chemotherapy. Ann Surg. 1982;196(3):305–15.
Article CAS PubMed PubMed Central Google Scholar
Yang JC, Chang AE, Baker AR, et al. Randomized prospective study of the benefit of adjuvant radiation therapy in the treatment of soft tissue sarcomas of the extremity. J Clin Oncol. 1998;16(1):197–203. https://doi.org/10.1200/JCO.1998.16.1.197.
Article CAS PubMed Google Scholar
O’Sullivan B, Davis AM, Turcotte R, et al. Preoperative versus postoperative radiotherapy in soft-tissue sarcoma of the limbs: a randomised trial. Lancet. 2002;359(9325):2235–41. https://doi.org/10.1016/S0140-6736(02)09292-9.
Eilber FR, Mirra JJ, Grant TT, Weisenburger T, Morton DL. Is amputation necessary for sarcomas? A seven-year experience with limb salvage. Ann Surg. 1980;192(4):431–8. https://doi.org/10.1097/00000658-198010000-00001.
Article CAS PubMed PubMed Central Google Scholar
Eilber FR, Morton DL, Eckardt J, Grant T, Weisenburger T. Limb salvage for skeletal and soft tissue sarcomas, Multidisciplinary preoperative therapy. Cancer. 1984;53(12):2579–84. https://doi.org/10.1002/1097-0142(19840615)53:12%3c2579::aid-cncr2820531202%3e3.0.co;2-v.
Article CAS PubMed Google Scholar
Engel CJ, Eilber FR, Rosen G, Selch MT, Fu YS. Preoperative chemotherapy for soft tissue sarcomas of the extremities: the experience at the University of California, Los Angeles. Cancer Treat Res. 1993;67:135–41. https://doi.org/10.1007/978-1-4615-3082-4_9.
Article CAS PubMed Google Scholar
Eilber FC, Rosen G, Eckardt J, et al. Treatment-induced pathologic necrosis: a predictor of local recurrence and survival in patients receiving neoadjuvant therapy for high-grade extremity soft tissue sarcomas. J Clin Oncol. 2001;19(13):3203–9. https://doi.org/10.1200/JCO.2001.19.13.3203.
Article CAS PubMed Google Scholar
Lu E, Perlewitz KS, Hayden JB, et al. Epirubicin and ifosfamide with preoperative radiation for high-risk soft tissue sarcomas. Ann Surg Oncol. 2018;25(4):920–7. https://doi.org/10.1245/s10434-018-6346-4.
Pennington JD, Eilber FC, Eilber FR, et al. Long-term outcomes with ifosfamide-based hypofractionated preoperative chemoradiotherapy for extremity soft tissue sarcomas. Am J Clin Oncol. 2018;41(12):1154–61. https://doi.org/10.1097/COC.0000000000000443.
Mack LA, Crowe PJ, Yang JL, et al. Preoperative chemoradiotherapy (modified Eilber protocol) provides maximum local control and minimal morbidity in patients with soft tissue sarcoma. Ann Surg Oncol. 2005;12(8):646–53. https://doi.org/10.1245/ASO.2005.03.064.
Spałek MJ, Koseła-Paterczyk H, Borkowska A, et al. Combined preoperative hypofractionated radiotherapy with doxorubicin-ifosfamide chemotherapy in marginally resectable soft tissue sarcomas: results of a phase 2 clinical trial. Int J Radiat Oncol Biol Phys. 2021;110(4):1053–63. https://doi.org/10.1016/j.ijrobp.2021.02.019.
Davis AM, O’Sullivan B, Turcotte R, et al. Late radiation morbidity following randomization to preoperative versus postoperative radiotherapy in extremity soft tissue sarcoma. Radiother Oncol. 2005;75(1):48–53. https://doi.org/10.1016/j.radonc.2004.12.020.
Salerno KE, Alektiar KM, Baldini EH, et al. Radiation therapy for treatment of soft tissue sarcoma in adults: executive summary of an ASTRO clinical practice guideline. Pract Radiat Oncol. 2021;11(5):339–51. https://doi.org/10.1016/j.prro.2021.04.005.
von Mehren M, Kane JM, Agulnik M, et al. Soft tissue sarcoma, version 2.2022, NCCN Clinical Practice Guidelines in Oncology. J Natl Compr Canc Netw. 2022;20(7):815–33. https://doi.org/10.6004/jnccn.2022.0035.
Wilkins A, Mossop H, Syndikus I, et al. Hypofractionated radiotherapy versus conventionally fractionated radiotherapy for patients with intermediate-risk localised prostate cancer: 2-year patient-reported outcomes of the randomised, non-inferiority, phase 3 CHHiP trial. Lancet Oncol. 2015;16(16):1605–16. https://doi.org/10.1016/S1470-2045(15)00280-6.
Article PubMed PubMed Central Google Scholar
Erlandsson J, Holm T, Pettersson D, et al. Optimal fractionation of preoperative radiotherapy and timing to surgery for rectal cancer (Stockholm III): a multicentre, randomised, non-blinded, phase 3, non-inferiority trial. Lancet Oncol. 2017;18(3):336–46. https://doi.org/10.1016/S1470-2045(17)30086-4.
Whelan TJ, Pignol JP, Levine MN, et al. Long-term results of hypofractionated radiation therapy for breast cancer. N Engl J Med. 2010;362(6):513–20. https://doi.org/10.1056/NEJMoa0906260.
Article CAS PubMed Google Scholar
Haviland JS, Owen JR, Dewar JA, et al. The UK Standardisation of Breast Radiotherapy (START) trials of radiotherapy hypofractionation for treatment of early breast cancer: 10-year follow-up results of two randomised controlled trials. Lancet Oncol. 2013;14(11):1086–94. https://doi.org/10.1016/S1470-2045(13)70386-3.
Murray Brunt A, Haviland JS, Wheatley DA, et al. Hypofractionated breast radiotherapy for 1 week versus 3 weeks (FAST-Forward): 5-year efficacy and late normal tissue effects results from a multicentre, non-inferiority, randomised, phase 3 trial. Lancet. 2020;395(10237):1613–26. https://doi.org/10.1016/S0140-6736(20)30932-6.
Article PubMed PubMed Central Google Scholar
Roohani S, Ehret F, Kobus M, et al. Preoperative hypofractionated radiotherapy for soft tissue sarcomas: a systematic review. Radiat Oncol. 2022;17(1):159. https://doi.org/10.1186/s13014-022-02072-9.
Article PubMed PubMed Central Google Scholar
Joyce R, Herlihy E, Lavan N, Gillham C. Hypofractionated preoperative radiation therapy for soft tissue sarcoma: a systematic review. Int J Radiat Oncol Biol Phys. 2024. https://doi.org/10.1016/j.ijrobp.2024.07.2151.
Haas RL, Floot BGJ, Scholten AN, et al. Cellular radiosensitivity of soft tissue sarcoma. Radiat Res. 2021;196(1):23–30. https://doi.org/10.1667/RADE-20-00226.1.
Article CAS PubMed Google Scholar
O’Sullivan B, Griffin AM, Dickie CI, et al. Phase 2 study of preoperative image-guided intensity-modulated radiation therapy to reduce wound and combined modality morbidities in lower extremity soft tissue sarcoma. Cancer. 2013;119(10):1878–84. https://doi.org/10.1002/cncr.27951.
Folkert M, Casey D, Berry S, et al. Femoral fracture in primary soft-tissue sarcoma of the thigh and groin treated with intensity-modulated radiation thearpy: observed vs. expected risk. Ann Surg Oncol. 2019;In Press.
Koseła-Paterczyk H, Szacht M, Morysiński T, et al. Preoperative hypofractionated radiotherapy in the treatment of localized soft tissue sarcomas. Eur J Surg Oncol. 2014;40(12):1641–7. https://doi.org/10.1016/j.ejso.2014.05.016.
Haas RLM, Delaney TF, O’Sullivan B, et al. Radiotherapy for management of extremity soft tissue sarcomas: why, when, and where? Int J Radiat Oncol Biol Phys. 2012;84(3):572–80. https://doi.org/10.1016/j.ijrobp.2012.01.062.
Koseła-Paterczyk H, Teterycz P, Spałek MJ, et al. Efficacy and safety of hypofractionated preoperative radiotherapy for primary locally advanced soft tissue sarcomas of limbs or trunk wall. Cancers (Basel). 2021;13(12):2981. https://doi.org/10.3390/cancers13122981.
Article CAS PubMed PubMed Central Google Scholar
Zagars GK, Ballo MT, Pisters PWT, Pollock RE, Patel SR, Benjamin RS. Preoperative vs. postoperative radiation therapy for soft tissue sarcoma: a retrospective comparative evaluation of disease outcome. Int J Radiat Oncol Biol Phys. 2003;56(2):482–8. https://doi.org/10.1016/s0360-3016(02)04510-8.
留言 (0)