Negrato CA, Gomes MB (2013) Historical facts of screening and diagnosing diabetes in pregnancy. Diabetol Metab Syndr 5(1):22
Article PubMed PubMed Central Google Scholar
Bashir M, Fagier Y, Ahmed B, Konje JC (2024) An overview of diabetes mellitus in pregnant women with obesity. Best Pract Res Clin Obstet Gynaecol. 93:102469
International Diabetes Federation (2019) Diabetes Atlas. 9th ed. International Diabetes Federation; Brussels, Belgium. Available online: http://www.diabetesatlas.org
Wang H, Li N, Chivese T, Werfalli M, Sun H, Yuen L, Yang X (2022) IDF diabetes atlas: estimation of global and regional gestational diabetes mellitus prevalence for 2021 by International Association of Diabetes in Pregnancy Study Group’s Criteria. Diabetes Res Clin Pract 2022(183):109050
Abouzid MR, Ali K, Elkhawas I, Elshafei SM (2022) An overview of diabetes mellitus in Egypt and the significance of integrating preventive cardiology in diabetes management. Cureus 14(7):e27066
PubMed PubMed Central Google Scholar
Saad H, Aziz AA, Emad E, Gaber M (2023) Awareness of gestational diabetes problem among Sohag Governorate women. Egypt J Intern Med 35(1):52
Johns EC, Denison FC, Norman JE, Reynolds RM (2018) Gestational diabetes mellitus: mechanisms, treatment, and complications. Trends Endocrinol Metab 29:743–754
Article CAS PubMed Google Scholar
Pathirana MM, Lassi ZS, Roberts CT, Andraweera PH (2020) Cardiovascular risk factors in offspring exposed to gestational diabetes mellitus in utero: systematic review and meta-analysis. J Dev Orig Health Dis 11:599–616
Sacks KN, Friger M, Shoham-Vardi I, Abokaf H, Spiegel E, Sergienko R, Landau D, Sheiner E (2016) Prenatal exposure to gestational diabetes mellitus as an independent risk factor for long-term neuropsychiatric morbidity of the offspring. Am J Obstet Gynecol 215(380):e1-380.e7
Heazell AE, Bernatavicius G, Warrander L, Brown MC, Dunn WB (2012) A metabolomic approach identifies differences in maternal serum in third trimester pregnancies that end in poor perinatal outcome. Reprod Sci 8:863–875
Diaz SO, Barros AS, Goodfellow BJ, Duarte IF, Galhano E, Pita C, Almeida MD, Carreira IM, Gil AM (2013) Second trimester maternal urine for the diagnosis of trisomy 21 and prediction of poor pregnancy outcomes. J Proteome Res 12(6):2946–2957
Article CAS PubMed Google Scholar
Baker SA, Rutter J (2023) Metabolites as signalling molecules. Nat Rev Mol Cell Biol 24(5):355–374
Article CAS PubMed Google Scholar
Jin Q, Ma RCW (2021) Metabolomics in diabetes and diabetic complications: insights from epidemiological studies. Cells 10(11):2832
Article CAS PubMed PubMed Central Google Scholar
Locci E, Bazzano G, Demontis R, Chighine A, Fanos V, d’Aloja E (2020) Exploring perinatal asphyxia by metabolomics. Metabolites 10(4):141
Article CAS PubMed PubMed Central Google Scholar
Moros G, Boutsikou T, Fotakis C, Iliodromiti Z, Sokou R, Katsila T, Xanthos T, Iacovidou N, Zoumpoulakis P (2021) Insights into intrauterine growth restriction based on maternal and umbilical cord blood metabolomics. Sci Rep 11(1):7824
Article CAS PubMed PubMed Central Google Scholar
Tong P, Huang FR, Xu J, Wu ZQ, Hu X, Ling M, Wang D, Wu BF, Yang DJ, Zhang AM (2022) Metabolomic changes of neonatal sepsis: an exploratory clinical study. Zhongguo Dang Dai Er Ke Za Zhi 24(6):675–680 (Chinese)
American Diabetes Association Professional Practice Committee (2022) 2. Classification and diagnosis of diabetes: standards of medical care in diabetes-2022. Diabetes Care 45(Suppl 1):S17–S38
Karkia R, Giacchino T, Watson H, Gough A, Ramadan G, Akolekar R (2023) Maternal and neonatal complications in pregnancies with and without pre-gestational diabetes mellitus. J Perinat Med 52(1):30–40
Kivilompolo M, Öhrnberg L, Orešič M, Hyötyläinen T (2013) Rapid quantitative analysis of carnitine and acylcarnitines by ultra-high performance-hydrophilic interaction liquid chromatography-tandem mass spectrometry. J Chromatogr A 31(1292):189–194
Xia J, Mandal R, Sinelnikov IV, Broadhurst D, Wishart DS (2012) MetaboAnalyst 2.0—a comprehensive server for metabolomic data analysis. Nucleic Acids Res 40(W1):W127–W133
Article CAS PubMed PubMed Central Google Scholar
Ng PC, Lam HS (2012) Biomarkers in neonatology: the next generation of tests. Neonatology 102(2):145–151
Peng S, Zhang J, Liu L, Zhang X, Huang Q, Alamdar A, Tian M, Shen H (2015) Newborn meconium and urinary metabolome response to maternal gestational diabetes mellitus: a preliminary case–control study. J Proteome Res 14(4):1799–1809
Article CAS PubMed Google Scholar
Dani C, Bresci C, Berti E, Ottanelli S, Mello G, Mecacci F, Breschi R, Hu X, Tenori L, Luchinat C (2014) Metabolomic profile of term infants of gestational diabetic mothers. J Matern Fetal Neonatal Med 27(6):537–542
Article CAS PubMed Google Scholar
Taricco E, Radaelli T, Rossi G, de Santis N, Bulfamante G, Avagliano L, Cetin I (2009) Effects of gestational diabetes on fetal oxygen and glucose levels in vivo. BJOG Int J Obstet Gynaecol 116:1729–1735
Guasch-Ferré M, Hruby A, Toledo E, Clish CB, Martínez-González MA, Salas-Salvadó J, Hu FB (2016) Metabolomics in prediabetes and diabetes: a systematic review and meta-analysis. Diabetes Care 39(5):833–846
Article PubMed PubMed Central Google Scholar
Lu Y-P, Reichetzeder C, Prehn C, von Websky K, Slowinski T, Chen Y-P, Yin L-H, Kleuser B, Yang X-S, Adamski J et al (2018) Fetal serum metabolites are independently associated with gestational diabetes mellitus. Cell Physiol Biochem 45:625–638
Article CAS PubMed Google Scholar
Adeva MM, Calviño J, Souto G, Donapetry C (2012) Insulin resistance and the metabolism of branched-chain amino acids in humans. Amino Acids 43(1):171–181
Article CAS PubMed Google Scholar
Lager S, Powell TL (2012) Regulation of nutrient transport across the placenta. J Pregnancy 2012:179827
Article PubMed PubMed Central Google Scholar
Agakidou E, Diamanti E, Papoulidis I, Papakonstantinou E, Stergioudas I, Sarafidis K, Drossou V, Evangeliou A (2013) Effect of gestational diabetes on circulating levels of maternal and neonatal carnitine. J Diabetes Metab 4(3):250
Zheng W, Yuan X, Zhao J, Han W, Huang J, Yan X, Zhang L, Li L, Wang S, Kong Y, Li G (2024) Neonatal amino acids and acylcarnitines associated with maternal blood glucose levels throughout pregnancy: insights from the Beijing Birth Cohort Study. Diabetes Care 232489
Reiss JD, Chang AL, Mayo JA, Bianco K, Lee HC, Stevenson DK, Shaw GM, Aghaeepour N, Sylvester KG (2022) Newborn screen metabolic panels reflect the impact of common disorders of pregnancy. Pediatr Res 92(2):490–497
Article CAS PubMed Google Scholar
Nicholas DA, Proctor EA, Agrawal M, Belkina AC, Van Nostrand SC, Panneerseelan-Bharath L, Jones AR 4th, Raval F, Ip BC, Zhu M, Cacicedo JM, Habib C, Sainz-Rueda N, Persky L, Sullivan PG, Corkey BE, Apovian CM, Kern PA, Lauffenburger DA, Nikolajczyk BS (2019) Fatty acid metabolites combine with reduced β oxidation to activate Th17 inflammation in human type 2 diabetes. Cell Metab 30(3):447-461.e5
Article CAS PubMed PubMed Central Google Scholar
Gil-Sanchez A, Koletzko B, Larqué E (2012) Current understanding of placental fatty acid transport. Curr Opin Clin Nutr Metab Care 15(3):265–272
Article CAS PubMed Google Scholar
Mihalik SJ, Goodpaster BH, Kelley DE, Chace DH, Vockley J, Toledo FG, DeLany JP (2010) Increased levels of plasma acylcarnitines in obesity and type 2 diabetes and identification of a marker of glucolipotoxicity. Obesity 18(9):1695–1700
Article CAS PubMed Google Scholar
Simmons D, Breier BH (2002) Fetal overnutrition in polynesian pregnan
留言 (0)