Deshmukh AA, Suk R, Shiels MS, Sonawane K, Nyitray AG, Liu Y, et al. Recent trends in squamous cell carcinoma of the Anus incidence and mortality in the United States, 2001–2015. JNCI: J Natl Cancer Inst. 2019;112(8):829–38.

Article  PubMed Central  Google Scholar 

Siegel RL, Miller KD, Fuchs HE, Jemal A, Cancer statistics. 2022. CA: a cancer journal for clinicians. 2022;72(1).

Roberts JR, Siekas LL, Kaz AM. Anal intraepithelial neoplasia: a review of diagnosis and management. World J Gastrointest Oncol. 2017;9(2):50–61.

Article  PubMed  PubMed Central  Google Scholar 

Stier EA, Clarke MA, Deshmukh AA, Wentzensen N, Liu Y, Poynten IM, et al. International Anal Neoplasia Society’s consensus guidelines for anal cancer screening. Int J Cancer. 2024;154(10):1694–702.

Article  CAS  PubMed  Google Scholar 

Selimagic A, Dozic A, Husic-Selimovic A, Tucakovic N, Cehajic A, Subo A et al. The role of inflammation in Anal Cancer. Diseases. 2022;10(2).

Ciombor KK, Ernst RD, Brown G. Diagnosis and diagnostic imaging of Anal Canal Cancer. Surg Oncol Clin N Am. 2017;26(1):45–55.

Article  PubMed  PubMed Central  Google Scholar 

Saraiya M, Unger ER, Thompson TD, Lynch CF, Hernandez BY, Lyu CW, et al. US assessment of HPV types in cancers: implications for current and 9-valent HPV vaccines. J Natl Cancer Inst. 2015;107(6):djv086.

Article  PubMed  PubMed Central  Google Scholar 

De Vuyst H, Clifford GM, Nascimento MC, Madeleine MM, Franceschi S. Prevalence and type distribution of human papillomavirus in carcinoma and intraepithelial neoplasia of the vulva, vagina and anus: a meta-analysis. Int J Cancer. 2009;124(7):1626–36.

Article  PubMed  Google Scholar 

Palefsky JM, Giuliano AR, Goldstone S, Moreira ED Jr, Aranda C, Jessen H, et al. HPV vaccine against anal HPV infection and anal intraepithelial neoplasia. N Engl J Med. 2011;365(17):1576–85.

Article  CAS  PubMed  Google Scholar 

Johnson LG, Madeleine MM, Newcomer LM, Schwartz SM, Daling JR. Anal cancer incidence and survival: the surveillance, epidemiology, and end results experience, 1973–2000. Cancer. 2004;101(2):281–8.

Article  PubMed  Google Scholar 

Frisch M, Glimelius B, van den Brule AJ, Wohlfahrt J, Meijer CJ, Walboomers JM, et al. Sexually transmitted infection as a cause of anal cancer. N Engl J Med. 1997;337(19):1350–8.

Article  CAS  PubMed  Google Scholar 

Evande R, Rana A, Biswas-Fiss EE, Biswas SB. Protein-DNA interactions regulate human papillomavirus DNA replication, transcription, and Oncogenesis. Int J Mol Sci. 2023;24(10).

Rasizadeh R, Aghbash PS, Mokhtarzadeh A, Poortahmasebi V, Oskouee MA, Nahand JS et al. Novel strategies in HPV–16–related cervical cancer treatment: an in vitro study of combined siRNA-E5 with oxaliplatin and ifosfamide chemotherapy. Gene. 2024:148904.

Gheit T. Mucosal and cutaneous human papillomavirus infections and Cancer Biology. Front Oncol. 2019;9:355.

Article  PubMed  PubMed Central  Google Scholar 

Baghi HB, Aghbash PS, Rasizadeh R, Poortahmasebi V, Alinezhad F. Cancers Associated with Human Papillomavirus: an overview of prevalence in Iran and the Middle East. Exploratory Res Hypothesis Med. 2024;9(2):115–27.

Article  Google Scholar 

Espinoza H, Ha KT, Pham TT, Espinoza JL. Genetic predisposition to Persistent Human papillomavirus-infection and Virus-Induced cancers. Microorganisms. 2021;9(10).

Latsuzbaia A, Wienecke-Baldacchino A, Tapp J, Arbyn M, Karabegović I, Chen Z, et al. Characterization and diversity of 243 complete human papillomavirus genomes in cervical swabs using next generation sequencing. Viruses. 2020;12(12):1437.

Article  CAS  PubMed  PubMed Central  Google Scholar 

Fatemipour M, Nahand JS, Azar MEF, Baghi HB, Taghizadieh M, Sorayyayi S, et al. Human papillomavirus and prostate cancer: the role of viral expressed proteins in the inhibition of anoikis and induction of metastasis. Microb Pathog. 2021;152:104576.

Article  CAS  PubMed  Google Scholar 

Alizon S, Murall CL, Bravo IG. Why human papillomavirus Acute infections Matter. Viruses. 2017;9(10).

Kombe Kombe AJ, Li B, Zahid A, Mengist HM, Bounda GA, Zhou Y, et al. Epidemiology and Burden of Human Papillomavirus and Related diseases, Molecular Pathogenesis, and vaccine evaluation. Front Public Health. 2020;8:552028.

Article  PubMed  Google Scholar 

Tanzi E, Canuti M. HPV infection and cervical Cancer. Global Health Essentials: Springer; 2023. pp. 109–16.

Google Scholar 

Pimple S, Mishra G. Cancer cervix: epidemiology and disease burden. Cytojournal. 2022;19:21.

Article  PubMed  PubMed Central  Google Scholar 

Chen W, Zhao Y, Xie X, Liu J, Li J, Zhao C, et al. Safety of a quadrivalent human papillomavirus vaccine in a phase 3, randomized, double-blind, placebo-controlled clinical trial among Chinese women during 90 months of follow-up. Vaccine. 2019;37(6):889–97.

Article  CAS  PubMed  Google Scholar 

Gee J, Weinbaum C, Sukumaran L, Markowitz LE. Quadrivalent HPV vaccine safety review and safety monitoring plans for nine-valent HPV vaccine in the United States. Hum Vaccines Immunotherapeutics. 2016;12(6):1406–17.

Article  Google Scholar 

Guerendiain D, Grigorescu R, Kirk A, Stevenson A, Holden MT, Pan J, et al. HPV status and HPV16 viral load in anal cancer and its association with clinical outcome. Cancer Med. 2022;11(22):4193–203.

Article  CAS  PubMed  PubMed Central  Google Scholar 

Sabatini ME, Chiocca S. Human papillomavirus as a driver of head and neck cancers. Br J Cancer. 2020;122(3):306–14.

Article  PubMed  Google Scholar 

De Martel C, Ferlay J, Franceschi S, Vignat J, Bray F, Forman D, et al. Global burden of cancers attributable to infections in 2008: a review and synthetic analysis. Lancet Oncol. 2012;13(6):607–15.

Article  PubMed  Google Scholar 

Ferlay J, Storm H, Whelan SL, Parkin DM. Cancer incidence in five continents. Cancer incidence in five continents2005.

Grulich AE, Poynten IM, Machalek DA, Jin F, Templeton DJ, Hillman RJ. The epidemiology of anal cancer. Sex Health. 2012;9(6):504–8.

Article  PubMed  Google Scholar 

Van der Zee R, Richel O, De Vries H, Prins J. The increasing incidence of anal cancer: can it be explained by trends in risk groups. Neth J Med. 2013;71(8):401–11.

PubMed  Google Scholar 

Ciardiello D, Guerrera LP, Maiorano BA, Parente P, Latiano TP, Di Maio M, et al. Immunotherapy in advanced anal cancer: is the beginning of a new era? Cancer Treat Rev. 2022;105:102373.

Article  CAS  PubMed  Google Scholar 

Rasi F, Zarredar H, Amini M, Onsori H, Dadashzadeh K, Khanmohammadi M, et al. Suppression of E6 Oncogene induces apoptosis in CaSki Cervical Cancer cells. Asian Pac J Cancer Prevention: APJCP. 2023;24(10):2289.

Article  Google Scholar 

Shiri Aghbash P, Hemmat N, Baradaran B, Bannazadeh Baghi H. siRNA-E6 sensitizes HPV-16-related cervical cancer through Oxaliplatin: an in vitro study on anti-cancer combination therapy. Eur J Med Res. 2023;28(1):1–13.

Article  Google Scholar 

Shiri Aghbash P, Hemmat N, Baradaran B, Bannazadeh Baghi H. siRNA-E6 sensitizes HPV-16-related cervical cancer through Oxaliplatin: an in vitro study on anti-cancer combination therapy. Eur J Med Res. 2023;28(1):42.

Article  CAS  PubMed  PubMed Central  Google Scholar 

Bown E, Shah V, Sridhar T, Boyle K, Hemingway D, Yeung JM. Cancers of the anal canal: diagnosis, treatment and future strategies. Future Oncol. 2014;10(8):1427–41.

Article  CAS  PubMed  Google Scholar 

Glynne-Jones R, Nilsson PJ, Aschele C, Goh V, Peiffert D, Cervantes A, et al. Anal cancer: ESMO–ESSO–ESTRO clinical practice guidelines for diagnosis, treatment and follow-up. Radiother Oncol. 2014;111(3):330–9.

Article  PubMed  Google Scholar 

Bushara O, Krogh K, Weinberg SE, Finkelman BS, Sun L, Liao J, et al. Human immunodeficiency virus infection promotes human papillomavirus-mediated anal squamous carcinogenesis: an immunologic and pathobiologic review. Pathobiology. 2022;89(1):1–12.

Article  CAS  PubMed  Google Scholar 

Donà MG, Giuliani M, Rollo F, Vescio MF, Benevolo M, Giglio A, et al. Incidence and clearance of anal high-risk human papillomavirus infection and their risk factors in men who have sex with men living with HIV. Sci Rep. 2022;12(1):184.

Article  PubMed  PubMed Central  Google Scholar 

Salati SA, Al Kadi A. Anal cancer–a review. Int J Health Sci. 2012;6(2):206.

Google Scholar 

Roberts JR, Siekas LL, Kaz AM. Anal intraepithelial neoplasia: a review of diagnosis and management. World J Gastrointest Oncol. 2017;9(2):50.

Article