The oncogenic role and prognostic value of PXDN in human stomach adenocarcinoma

Diniz F, Lamas S, Osorio H, Aguiar P, Freitas D, Gartner F, Sarmento B, Reis CA, Gomes J. Nanoparticles targeting Sialyl-Tn for efficient tyrosine kinase inhibitor delivery in gastric cancer. Acta Biomater. 2023;170:142–54.

Article  CAS  PubMed  Google Scholar 

Guo L, Fang T, Jiang Y, Liu D. IRF7 is a Prognostic Biomarker and Associated with Immune Infiltration in Stomach Adenocarcinoma. Int J Gen Med. 2021;14:9887–902.

Article  CAS  PubMed  PubMed Central  Google Scholar 

Shang F, Cao Y, Wan L, Ren Z, Wang X, Huang M, Guo Y. Comparison of Helicobacter pylori positive and negative gastric cancer via multi-omics analysis. mBio 2023:e0153123.

Nevo Y, Ferri L. Current management of gastric adenocarcinoma: a narrative review. J Gastrointest Oncol. 2023;14(4):1933–48.

Article  PubMed  PubMed Central  Google Scholar 

Shin WS, Xie F, Chen B, Yu P, Yu J, To KF, Kang W. Updated Epidemiology of Gastric Cancer in Asia: Decreased Incidence but Still a Big Challenge. Cancers (Basel) 2023, 15(9).

Anashkina AA, Leberfarb EY, Orlov YL. Recent Trends in Cancer Genomics and Bioinformatics Tools Development. Int J Mol Sci 2021, 22(22).

Mou Z, Spencer J, McGrath JS, Harries LW. Comprehensive analysis of alternative splicing across multiple transcriptomic cohorts reveals prognostic signatures in prostate cancer. Hum Genomics. 2023;17(1):97.

Article  CAS  PubMed  PubMed Central  Google Scholar 

Cheng Y, Shen Y, Fang Q, Duan S, Wang Y, Dai X, Chen Y. Identification of epithelial-mesenchymal transition-related biomarkers in lung adenocarcinoma using bioinformatics and lab experiments. Aging 2023, 15.

Lynch E, Duffy AG, Kelly RJ. Brave new world-new and emerging treatments for gastric cancer. Chin Clin Oncol 2023.

Marinelli D, Gallina FT, Pannunzio S, Di Civita MA, Torchia A, Giusti R, Gelibter AJ, Roberto M, Verrico M, Melis E, et al. Surgical and survival outcomes with perioperative or neoadjuvant immune-checkpoint inhibitors combined with platinum-based chemotherapy in resectable NSCLC: A systematic review and meta-analysis of randomised clinical trials. Crit Rev Oncol Hematol. 2023;192:104190.

Article  PubMed  Google Scholar 

Zhao Y, Bai Y, Shen M, Li Y. Therapeutic strategies for gastric cancer targeting immune cells: Future directions. Front Immunol. 2022;13:992762.

Article  CAS  PubMed  PubMed Central  Google Scholar 

Yoon J, Kim TY, Oh DY. Recent Progress in Immunotherapy for Gastric Cancer. J Gastric Cancer. 2023;23(1):207–23.

Article  PubMed  PubMed Central  Google Scholar 

Tsilimigras DI, Ntanasis-Stathopoulos I, Moris D, Pawlik TM. Liver Tumor Microenvironment. Adv Exp Med Biol. 2020;1296:227–41.

Article  CAS  PubMed  Google Scholar 

Cui H, Lian J, Xu B, Yu Z, Xiang H, Shi J, Gao Y, Han T. Identification of a bile acid and bile salt metabolism-related lncRNA signature for predicting prognosis and treatment response in hepatocellular carcinoma. Sci Rep. 2023;13(1):19512.

Article  CAS  PubMed  PubMed Central  Google Scholar 

Boelaars K, Goossens-Kruijssen L, Wang D, de Winde CM, Rodriguez E, Lindijer D, Springer B, van der Haar Avila I, de Haas A, Wehry L et al. Unraveling the impact of sialic acids on the immune landscape and immunotherapy efficacy in pancreatic cancer. J Immunother Cancer 2023, 11(11).

Nelson RE, Fessler LI, Takagi Y, Blumberg B, Keene DR, Olson PF, Parker CG, Fessler JH. Peroxidasin: a novel enzyme-matrix protein of Drosophila development. EMBO J. 1994;13(15):3438–47.

Article  CAS  PubMed  PubMed Central  Google Scholar 

Kovacs HA, Lazar E, Varady G, Sirokmany G, Geiszt M. Characterization of the Proprotein Convertase-Mediated Processing of Peroxidasin and Peroxidasin-like Protein. Antioxid (Basel) 2021, 10(10).

Bhave G, Cummings CF, Vanacore RM, Kumagai-Cresse C, Ero-Tolliver IA, Rafi M, Kang JS, Pedchenko V, Fessler LI, Fessler JH, et al. Peroxidasin forms sulfilimine chemical bonds using hypohalous acids in tissue genesis. Nat Chem Biol. 2012;8(9):784–90.

Article  CAS  PubMed  PubMed Central  Google Scholar 

Dougan J, Hawsawi O, Burton LJ, Edwards G, Jones K, Zou J, Nagappan P, Wang G, Zhang Q, Danaher A et al. Proteomics-Metabolomics Combined Approach Identifies Peroxidasin as a Protector against Metabolic and Oxidative Stress in Prostate Cancer. Int J Mol Sci 2019, 20(12).

Kim HK, Ham KA, Lee SW, Choi HS, Kim HS, Kim HK, Shin HS, Seo KY, Cho Y, Nam KT et al. Biallelic Deletion of Pxdn in Mice Leads to Anophthalmia and Severe Eye Malformation. Int J Mol Sci 2019, 20(24).

Zheng YZ, Liang L. High expression of PXDN is associated with poor prognosis and promotes proliferation, invasion as well as migration in ovarian cancer. Ann Diagn Pathol. 2018;34:161–5.

Article  PubMed  Google Scholar 

Kurihara-Shimomura M, Sasahira T, Shimomura H, Kirita T. Peroxidan Plays a Tumor-Promoting Role in Oral Squamous Cell Carcinoma. Int J Mol Sci 2020, 21(15).

Chen Y, Zhou W, Gong Y, Ou X. Identification of ASF1B as a prognostic marker for liver cancer by meta-analysis and its immune value revealed by a comprehensive pan-cancer analysis of 33 human cancers. Prz Gastroenterol. 2023;18(3):249–65.

CAS  PubMed  PubMed Central  Google Scholar 

Li L, Wang F, Deng Z, Zhang G, Zhu L, Zhao Z, Liu R. DCLRE1B promotes tumor progression and predicts immunotherapy response through METTL3-mediated m6A modification in pancreatic cancer. BMC Cancer. 2023;23(1):1073.

Article  CAS  PubMed  PubMed Central  Google Scholar 

Zhang S, Wan X, Lv M, Li C, Chu Q, Wang G. TMEM92 acts as an immune-resistance and prognostic marker in pancreatic cancer from the perspective of predictive, preventive, and personalized medicine. EPMA J. 2022;13(3):519–34.

Article  PubMed  PubMed Central  Google Scholar 

Shi W, Ding W, Zhao Z, Wang R, Wang F, Tang Y, Zhu J, Su C, Zhao X, Liu L. Peroxidase is a novel potential marker in glioblastoma through bioinformatics method and experimental validation. Front Genet. 2022;13:990344.

Article  CAS  PubMed  PubMed Central  Google Scholar 

Duan HX, Li BW, Zhuang X, Wang LT, Cao Q, Tan LH, Qu GF, Xiao S. TCF21 inhibits tumor-associated angiogenesis and suppresses the growth of cholangiocarcinoma by targeting PI3K/Akt and ERK signaling. Am J Physiol Gastrointest Liver Physiol. 2019;316(6):G763–73.

Article  CAS  PubMed  Google Scholar 

Wu J, Yao J, Jia S, Yao X, Shao J, Cao W, Ma S, Yao X, Li H. A cuproptosis-related lncRNA signature for predicting prognosis and immune response in hepatocellular carcinoma. Heliyon. 2023;9(9):e19352.

Article  CAS  PubMed  PubMed Central  Google Scholar 

Shi T, Ma Y, Yu L, Jiang J, Shen S, Hou Y, Wang T. Cancer Immunotherapy: A Focus on the Regulation of Immune Checkpoints. Int J Mol Sci 2018, 19(5).

Kim DJ, Kang JH, Kim JW, Cheon MJ, Kim SB, Lee YK, Lee BC. Evaluation of optimal methods and ancestries for calculating polygenic risk scores in East Asian population. Sci Rep. 2023;13(1):19195.

Article  CAS  PubMed  PubMed Central  Google Scholar 

Tauber S, Jais A, Jeitler M, Haider S, Husa J, Lindroos J, Knofler M, Mayerhofer M, Pehamberger H, Wagner O, et al. Transcriptome analysis of human cancer reveals a functional role of heme oxygenase-1 in tumor cell adhesion. Mol Cancer. 2010;9:200.

Article  PubMed  PubMed Central  Google Scholar 

Zhou X, Sun Q, Xu C, Zhou Z, Chen X, Zhu X, Huang Z, Wang W, Shi Y. A systematic pan-cancer analysis of PXDN as a potential target for clinical diagnosis and treatment. Front Oncol. 2022;12:952849.

Article  CAS  PubMed  PubMed Central  Google Scholar 

Datta N, Chakraborty S, Basu M, Ghosh MK. Tumor Suppressors Having Oncogenic Functions: The Double Agents. Cells 2020, 10(1).

Pastushenko I, Blanpain C. EMT Transition States during Tumor Progression and Metastasis. Trends Cell Biol. 2019;29(3):212–26.

Article  CAS  PubMed  Google Scholar 

Lugano R, Ramachandran M, Dimberg A. Tumor angiogenesis: causes, consequences, challenges and opportunities. Cell Mol Life Sci. 2020;77(9):1745–70.

Article  CAS  PubMed  Google Scholar 

Yang Y, Gao M, Lin Z, Chen L, Jin Y, Zhu G, Wang Y, Jin T. DEK promoted EMT and angiogenesis through regulating PI3K/AKT/mTOR pathway in triple-negative breast cancer. Oncotarget. 2017;8(58):98708–22.

Article  PubMed  PubMed Central  Google Scholar 

Zhao C, Liu Y, Meng J, Wang X, Liu X, Li W, Zhou Q, Xiang J, Li N, Hou S. LGALS3BP in Microglia Promotes Retinal Angiogenesis Through PI3K/AKT Pathway During Hypoxia. Invest Ophthalmol Vis Sci. 2022;63(8):25.

Article  CAS  PubMed  PubMed Central  Google Scholar 

Shao Q, Zhang Z, Cao R, Zang H, Pei W, Sun T. CPA4 Promotes EMT in Pancreatic Cancer via Stimulating PI3K-AKT-mTOR Signaling. Onco Targets Ther. 2020;13:8567–80.

Article  CAS  PubMed  PubMed Central  Google Scholar 

留言 (0)

沒有登入
gif