Hunter, R.W. and M.A. Bailey, Hyperkalemia: pathophysiology, risk factors and consequences. Nephrol Dial Transplant, 2019. 34(Suppl 3): p. iii2-iii11.

McDonagh TA et al (2021) 2021 ESC Guidelines for the diagnosis and treatment of acute and chronic heart failure. Eur Heart J 42(36):3599–3726

Article  CAS  PubMed  Google Scholar 

Rafique Z et al (2021) Hyperkalemia management in the emergency department: an expert panel consensus. J Am Coll Emerg Physicians Open 2(5):e12572

Article  PubMed  PubMed Central  Google Scholar 

KDIGO (2024) clinical practice guideline for the evaluation and management of chronic kidney disease. Kidney Int 105(4s):S117-s314

Google Scholar 

Larivée NL et al (2023) Hyperkalemia: prevalence, predictors and emerging treatments. Cardiol Ther 12(1):35–63

Article  PubMed  Google Scholar 

Hougen I et al (2021) Hyperkalemia and its association with mortality, cardiovascular events, hospitalizations, and intensive care unit admissions in a population-based retrospective cohort. Kidney Int Rep 6(5):1309–1316

Article  PubMed  PubMed Central  Google Scholar 

Romero-González G et al (2022) The “FIFTY SHADOWS” of the RALES trial: lessons about the potential risk of dietary potassium supplementation in patients with chronic kidney disease. J Clin Med 11(14):3970

Article  PubMed  PubMed Central  Google Scholar 

Francis A et al (2024) Chronic kidney disease and the global public health agenda: an international consensus. Nature Reviews Nephrology 20(7):473–485

Article  PubMed  Google Scholar 

Savarese G et al (2023) Global burden of heart failure: a comprehensive and updated review of epidemiology. Cardiovasc Res 118(17):3272–3287

Article  PubMed  Google Scholar 

Johns EJ (2024) Functional insights into the cardiorenal syndrome. Hypertens Res 47(6):1747–1749

Article  PubMed  Google Scholar 

Silva-Cardoso J et al (2021) Management of RAASi-associated hyperkalemia in patients with cardiovascular disease. Heart Fail Rev 26(4):891–896

Article  CAS  PubMed  PubMed Central  Google Scholar 

De Nicola L et al (2024) Recommendations for the management of hyperkalemia in patients receiving renin–angiotensin–aldosterone system inhibitors. Intern Emerg Med 19(2):295–306

Article  PubMed  Google Scholar 

Collins AJ et al (2017) Association of serum potassium with all-cause mortality in patients with and without heart failure, chronic kidney disease, and/or diabetes. Am J Nephrol 46(3):213–221

Article  CAS  PubMed  Google Scholar 

Sharma A et al (2021) Healthcare resource utilization and costs associated with hyperkalemia in a large managed care population. J Pharm Health Serv Res 12(1):35–41

Article  Google Scholar 

McDonagh TA et al (2023) 2023 Focused Update of the 2021 ESC Guidelines for the diagnosis and treatment of acute and chronic heart failure: developed by the task force for the diagnosis and treatment of acute and chronic heart failure of the European Society of Cardiology (ESC) With the special contribution of the Heart Failure Association (HFA) of the ESC. Eur Heart J 44(37):3627–3639

Article  CAS  PubMed  Google Scholar 

Palmer BF et al (2021) Clinical management of hyperkalemia. Mayo Clin Proc 96(3):744–762

Article  CAS  PubMed  Google Scholar 

An J et al (2023) Discontinuation of renin-angiotensin-aldosterone system inhibitors secondary to hyperkalemia translates into higher cardiorenal outcomes. Am J Nephrol 54(7–8):258–267

Article  CAS  PubMed  Google Scholar 

Svensson MK et al (2024) Hyperkalaemia-related reduction of RAASi treatment associates with more subsequent inpatient care. Nephrology Dialysis Transplantation 39(8):1258

Article  PubMed Central  Google Scholar 

Noel JA et al (2019) Risk of Hospitalization for serious adverse gastrointestinal events associated with sodium polystyrene sulfonate use in patients of advanced age. JAMA Intern Med 179(8):1025–1033

Article  PubMed  PubMed Central  Google Scholar 

Sinnathamby ES et al (2024) Hyperkalemia: pharmacotherapies and clinical considerations. Cureus 16(1):e52994

PubMed  PubMed Central  Google Scholar 

Vidal H, et al (2024) Calcium polystyrene sulfonate induced colitis: advanced characterization of crystal nature with infrared spectroscopy. Clinical Kidney Journal 17(8): https://doi.org/10.1093/ckj/sfae210

Paolillo S et al (2024) Novel potassium binders to optimize RAASi therapy in heart failure: a systematic review and meta-analysis. Eur J Intern Med 119:109–117

Article  CAS  PubMed  Google Scholar 

Abuelazm M et al (2024) The efficacy and safety of new potassium binders on renin-angiotensin-aldosterone system inhibitor optimization in heart failure patients: a systematic review and meta-analysis. ESC Heart Fail 11(1):28–43

Article  PubMed  Google Scholar 

Clase CM et al (2020) Potassium homeostasis and management of dyskalemia in kidney diseases: conclusions from a Kidney Disease: Improving Global Outcomes (KDIGO) Controversies Conference. Kidney Int 97(1):42–61

Article  CAS  PubMed  Google Scholar 

Kim MJ, Valerio C, Knobloch GK (2023) Potassium disorders: hypokalemia and hyperkalemia. Am Fam Physician 107(1):59–70

PubMed  Google Scholar 

Ben Salem C et al (2014) Drug-INDUCED HYPERKALEmia. Drug Saf 37(9):677–692

Article  CAS  PubMed  Google Scholar 

Massicotte-Azarniouch D et al (2023) Managing hyperkalemia in the modern era: a case-based approach. Kidney Int Rep 8(7):1290–1300

Article  PubMed  PubMed Central  Google Scholar 

Ferreira JP et al (2020) Abnormalities of potassium in heart failure: JACC State-of-the-Art Review. J Am Coll Cardiol 75(22):2836–2850

Article  CAS  PubMed  Google Scholar 

Fearon ER, Vogelstein B (1990) A genetic model for colorectal tumorigenesis. Cell 61(5):759–767

Article  CAS  PubMed  Google Scholar 

Humphrey T et al (2022) How common is hyperkalaemia? A systematic review and meta-analysis of the prevalence and incidence of hyperkalaemia reported in observational studies. Clin Kidney J 15(4):727–737

Article  PubMed  Google Scholar 

Kovesdy CP et al (2018) Serum potassium and adverse outcomes across the range of kidney function: a CKD Prognosis Consortium meta-analysis. Eur Heart J 39(17):1535–1542

Article  CAS  PubMed  PubMed Central  Google Scholar 

Rosano GMC et al (2018) Expert consensus document on the management of hyperkalaemia in patients with cardiovascular disease treated with renin angiotensin aldosterone system inhibitors: coordinated by the Working Group on Cardiovascular Pharmacotherapy of the European Society of Cardiology. European Heart Journal - Cardiovascular Pharmacotherapy 4(3):180–188

Article  PubMed  Google Scholar 

Albasri A et al (2021) Association between antihypertensive treatment and adverse events: systematic review and meta-analysis. BMJ 372:n189

Article  PubMed  PubMed Central  Google Scholar 

Kanda E et al (2023) Clinical impact of suboptimal RAASi therapy following an episode of hyperkalemia. BMC Nephrol 24(1):18

Article  CAS  PubMed  PubMed Central  Google Scholar 

Trevisan M et al (2018) Incidence, predictors and clinical management of hyperkalaemia in new users of mineralocorticoid receptor antagonists. Eur J Heart Fail 20(8):1217–1226

Article  CAS  PubMed  Google Scholar 

Linde C et al (2019) Real-world associations of renin-angiotensin-aldosterone system inhibitor dose, hyperkalemia, and adverse clinical outcomes in a cohort of patients with new-onset chronic kidney disease or heart failure in the United Kingdom. J Am Heart Assoc 8(22):e012655