Kwok M, Oldreive C, Rawstron AC, Goel A, Papatzikas G, Jones RE, et al. Integrative analysis of spontaneous CLL regression highlights genetic and microenvironmental interdependency in CLL. Blood. 2020;135:411–28.
Zurli V, Wimmer G, Cattaneo F, Candi V, Cencini E, Gozzetti A, et al. Ectopic ILT3 controls BCR-dependent activation of Akt in B-cell chronic lymphocytic leukemia. Blood. 2017;130:2006–17.
Article CAS PubMed Google Scholar
Deng M, Gui X, Kim J, Xie L, Chen W, Li Z, et al. LILRB4 signalling in leukaemia cells mediates T cell suppression and tumour infiltration. Nature. 2018;562:605–9.
Article CAS PubMed PubMed Central Google Scholar
Mahley RW. Apolipoprotein E: cholesterol transport protein with expanding role in cell biology. Science. 1988;240:622–30.
Article CAS PubMed Google Scholar
Farrer LA, Cupples LA, Haines JL, Hyman B, Kukull WA, Mayeux R, et al. Effects of age, sex, and ethnicity on the association between apolipoprotein E genotype and Alzheimer disease: a meta-analysis. J Am Med Assoc. 1997;278:1349–56.
Tavazoie MF, Pollack I, Tanqueco R, Ostendorf BN, Reis BS, Gonsalves FC, et al. LXR/ApoE activation restricts innate immune suppression in cancer. Cell. 2018;172:825–.e18.
Article CAS PubMed PubMed Central Google Scholar
Bancaro N, Calì B, Troiani M, Elia AR, Arzola RA, Attanasio G, et al. Apolipoprotein E induces pathogenic senescent-like myeloid cells in prostate cancer. Cancer Cell. 2023;41:602–.e11.
Article CAS PubMed Google Scholar
Ostendorf BN, Bilanovic J, Adaku N, Tafreshian KN, Tavora B, Vaughan RD, et al. Common germline variants of the human APOE gene modulate melanoma progression and survival. Nat Med. 2020;26:1048–53.
Article CAS PubMed PubMed Central Google Scholar
Huang YWA, Zhou B, Wernig M, Südhof TC. ApoE2, ApoE3, and ApoE4 differentially stimulate APP transcription and Aβ secretion. Cell. 2017;168:427–441.e21.
Article CAS PubMed PubMed Central Google Scholar
Jiang X, Stockwell BR, Conrad M. Ferroptosis: mechanisms, biology and role in disease. Nat Rev Mol Cell Biol. 2021;22:266–82.
Article PubMed PubMed Central Google Scholar
Vaisitti T, Braggio E, Allan JN, Arruga F, Serra S, Zamo A, et al. Novel Richter syndrome xenograft models to study genetic architecture, biology, and therapy responses. Cancer Res. 2018;78:3413–20.
Article CAS PubMed Google Scholar
Vaisitti T, Arruga F, Vitale N, Lee TT, Ko M, Chadburn A, et al. ROR1 targeting with the antibody-drug conjugate VLS-101 is effective in Richter syndrome patient-derived xenograft mouse models. Blood. 2021;137:3365–77.
Article CAS PubMed PubMed Central Google Scholar
Lee S, Chung CYS, Liu P, Craciun L, Nishikawa Y, Bruemmer KJ, et al. Activity-based sensing with a metal-directed acyl imidazole strategy reveals cell type-dependent pools of labile brain copper. J Am Chem Soc. 2020;142:14993–5003.
Article CAS PubMed PubMed Central Google Scholar
Murray MB, Leak LB, Lee WC, Dixon SJ. Protocol for detection of ferroptosis in cultured cells. STAR Protoc. 2023;4:102457.
Article CAS PubMed PubMed Central Google Scholar
Williams DJ, Puhl HL, Ikeda SR. A simple, highly efficient method for heterologous expression in mammalian primary neurons using cationic lipid-mediated mRNA transfection. Front Neurosci. 2010;4:1–20.
Nardi F, Pezzella L, Drago R, Di Rita A, Simoncelli M, Marotta G, et al. Assessing gene function in human B cells: CRISPR/Cas9-based gene editing and mRNA-based gene expression in healthy and tumor cells. Eur J Immunol. 2022;52:1362–5.
Article CAS PubMed Google Scholar
Schleiss C, Ilias W, Tahar O, Güler Y, Miguet L, Mayeur-Rousse C, et al. BCR-associated factors driving chronic lymphocytic leukemia cells proliferation ex vivo. Sci Rep. 2019;9:1–12.
Uchida Y, Ito S, Nukina N. Sandwich ELISA for the measurement of Apo-E4 levels in serum and the estimation of the allelic status of Apo-E4 isoforms. J Clin Lab Anal. 2000;14:260–4.
Article CAS PubMed Google Scholar
Thomas JP, Bachowski GJ, Girotti AW. Inhibition of cell membrane lipid peroxidation by cadmium- and zinc-metallothioneins. Biochim Biophys Acta. 1986;884:448–61.
Article CAS PubMed Google Scholar
Orr AL, Kim C, Jimenez-Morales D, Newton BW, Johnson JR, Krogan NJ, et al. Neuronal apolipoprotein E4 expression results in proteome-wide alterations and compromises bioenergetic capacity by disrupting mitochondrial function. J Alzheimer’s Dis. 2019;68:991–1011.
Stockwell BR, Friedmann Angeli JP, Bayir H, Bush AI, Conrad M, Dixon SJ, et al. Ferroptosis: a regulated cell death nexus linking metabolism, redox biology, and disease. Cell. 2017;171:273–85.
Article CAS PubMed PubMed Central Google Scholar
Koers J, Marsman C, Steuten J, Tol S, Derksen NIL, ten Brinke A, et al. Oxygen level is a critical regulator of human B cell differentiation and IgG class switch recombination. Front. Immunol. 2022;13:1082154. https://doi.org/10.3389/fimmu.2022.1082154.
Cobine PA, Moore SA, Leary SC. Getting out what you put in: copper in mitochondria and its impacts on human disease. Biochim Biophys Acta—Mol Cell Res. 2021;1868:118867.
Article CAS PubMed Google Scholar
Miyata M, Smith JD. Apolipoprotein E allele-specific antioxidant activity and effects on cytotoxicity by oxidative insults and β-amyloid peptides. Nat Genet. 1996;14:55–61.
Article CAS PubMed Google Scholar
Zurli V, Montecchi T, Heilig R, Poschke I, Volkmar M, Wimmer G, et al. Phosphoproteomics of CD2 signaling reveals AMPK-dependent regulation of lytic granule polarization in cytotoxic T cells. Sci Signal. 2020;13. https://doi.org/10.1126/scisignal.aaz1965.
Tsvetkov P, Detappe A, Cai K, Keys HR, Brune Z, Ying W, et al. Mitochondrial metabolism promotes adaptation to proteotoxic stress. Nat Chem Biol. 2019;15:681–9.
Article CAS PubMed PubMed Central Google Scholar
Krasnovskaya O, Naumov A, Guk D, Gorelkin P, Erofeev A, Beloglazkina E, et al. Copper coordination compounds as biologically active agents. Int J Mol Sci. 2020;21. https://doi.org/10.3390/ijms21113965.
Ong G, Logue SE. Unfolding the interactions between endoplasmic reticulum stress and oxidative stress. Antioxidants. 2023;12. https://doi.org/10.3390/antiox12050981.
Zhang Z, Zhang L, Zhou L, Lei Y, Zhang Y, Huang C. Redox signaling and unfolded protein response coordinate cell fate decisions under ER stress. Redox Biol. 2019;25:101047.
Article CAS PubMed Google Scholar
Shimizu Y, Hendershot LM. Oxidative folding: cellular strategies for dealing with the resultant equimolar production of reactive oxygen species. Antioxid Redox Signal. 2009;11:2317–31.
Article CAS PubMed PubMed Central Google Scholar
Zhou Q, Wang X, Zhang Y, Wang L, Chen Z. Inhibition of AEBP1 predisposes cisplatin-resistant oral cancer cells to ferroptosis. BMC Oral Health. 2022;22:478.
Article CAS PubMed PubMed Central Google Scholar
Sun X, Ou Z, Xie M, Kang R, Fan Y, Niu X, et al. HSPB1 as a novel regulator of ferroptotic cancer cell death. Oncogene. 2015;34:5617–25.
Article CAS PubMed PubMed Central Google Scholar
Tang D, Chen X, Kang R, Kroemer G. Ferroptosis: molecular mechanisms and health implications. Cell Res. 2021;31:107–25.
留言 (0)