Parisi R, Symmons DP, Griffiths CE, Ashcroft DM. Global epidemiology of psoriasis: a systematic review of incidence and prevalence. J Invest Dermatology. 2013;133:377–85.

Article  CAS  Google Scholar 

Bugaut H, Aractingi S. Major role of the IL17/23 axis in psoriasis supports the development of new targeted therapies. Front Immunol. 2021;12:621956.

Article  CAS  PubMed  PubMed Central  Google Scholar 

Armstrong AW, Read C. Pathophysiology, clinical presentation, and treatment of psoriasis: a review. JAMA. 2020;323:1945–60.

Article  CAS  PubMed  Google Scholar 

Gotesman R.D., Vender R. Bimekizumab for Moderate-to-severe plaque psoriasis. Skin Ther Lett. 2021;26:1–4. https://europepmc.org/article/med/34077151. (accessed March 23, 2024).

Google Scholar 

Xing X, Yang J, Yang X, Wei Y, Zhu L, Gao D, Li M. IL-17A induces endothelial inflammation in systemic sclerosis via the ERK signaling pathway. PLoS ONE. 2013;8:e85032.

Article  PubMed  PubMed Central  Google Scholar 

Mudigonda P, Mudigonda T, Feneran AN, Alamdari HS, Sandoval L, Feldman SR. Interleukin-23 and interleukin-17: importance in pathogenesis and therapy of psoriasis. Dermatol Online J 18 (2012).

Dimon-Gadal S, Raynaud F, Evain-Brion D, Keryer G. MAP kinase abnormalities in hyperproliferative cultured fibroblasts from psoriatic skin. J Invest Dermatology. 1998;110:872–9.

Article  CAS  Google Scholar 

Boonpethkaew S, Meephansan J, Ponnikorn S, Jumlongpim O, Juntongjin P, Chakkavittumrong P, Wongpiyabovorn J, Morita A, Komine M. Exploring the role of growth factors as potential regulators in psoriatic plaque formation. Exp Dermatol. 2023;32:1924–34.

Article  CAS  PubMed  Google Scholar 

Canavese M, Altruda F, Ruzicka T, Schauber J. Vascular endothelial growth factor (VEGF) in the pathogenesis of psoriasis—a possible target for novel therapies? J Dermatol Sci. 2010;58:171–6.

Article  CAS  PubMed  Google Scholar 

Zepp JA, Zhao J, Liu C, Bulek K, Wu L, Chen X, Hao Y, Wang Z, Wang X, Ouyang W. IL-17A–induced PLET1 expression contributes to tissue repair and colon tumorigenesis. J Immunol. 2017;199:3849–57.

Article  CAS  PubMed  Google Scholar 

Page ME, Lombard P, Ng F, Göttgens B, Jensen KB. The epidermis comprises autonomous compartments maintained by distinct stem cell populations. Cell Stem Cell. 2013;13:471–82.

Article  CAS  PubMed  PubMed Central  Google Scholar 

Raymond K, Richter A, Kreft M, Frijns E, Janssen H, Slijper M, Praetzel-Wunder S, Langbein L, Sonnenberg A. Expression of the orphan protein Plet-1 during trichilemmal differentiation of anagen hair follicles. J Invest Dermatology. 2010;130:1500–13.

Article  CAS  Google Scholar 

De Craene B, Denecker G, Vermassen P, Taminau J, Mauch C, Derore A, Jonkers J, Fuchs E, Berx G. Epidermal snail expression drives skin cancer initiation and progression through enhanced cytoprotection, epidermal stem/progenitor cell expansion and enhanced metastatic potential. Cell Death Differ. 2014;21:310–20.

Article  PubMed  Google Scholar 

Marchetti M, De Berardis B, Bigioni I, Mariano A, Superti F. Scotto d’Abusco, in Vitro Antiviral and anti-inflammatory activities of N-Acetylglucosamine: development of an Alternative and Safe Approach to fight viral respiratory infections. Int J Mol Sci. 2023;24:5129.

Article  CAS  PubMed  PubMed Central  Google Scholar 

Lee S-U, Li CF, Mortales C-L, Pawling J, Dennis JW, Grigorian A, Demetriou M. Increasing cell permeability of N-acetylglucosamine via 6-acetylation enhances capacity to suppress T-helper 1 (TH1)/TH17 responses and autoimmunity. PLoS ONE. 2019;14:e0214253.

Article  CAS  PubMed  PubMed Central  Google Scholar 

Tan R, Zhong X, Han R, Xie K, Jia J, Yang Y, Cheng M, Yang C, Lan H, Wang L. Macrophages mediate psoriasis via mincle-dependent mechanism in mice. Cell Death Discovery. 2023;9:140. https://www.nature.com/articles/s41420-023-01444-8. (accessed March 24, 2024).

Article  CAS  PubMed  PubMed Central  Google Scholar 

Chen J-K, Shen C-R, Liu C-L. N-acetylglucosamine: production and applications. Mar Drugs. 2010;8:2493–516.

Article  CAS  PubMed  PubMed Central  Google Scholar 

Bettelli E, Korn T, Oukka M, Kuchroo VK. Induction and effector functions of TH17 cells. Nature. 2008;453:1051–7.

Article  CAS  PubMed  PubMed Central  Google Scholar 

Lin AM, Rubin CJ, Khandpur R, Wang JY, Riblett M, Yalavarthi S, Villanueva EC, Shah P, Kaplan MJ, Bruce AT. Mast cells and neutrophils release IL-17 through extracellular trap formation in psoriasis. J Immunol. 2011;187:490–500.

Article  CAS  PubMed  Google Scholar 

Van Der Fits L, Mourits S, Voerman JS, Kant M, Boon L, Laman JD, Cornelissen F, Mus A-M, Florencia E, Prens EP. Imiquimod-induced psoriasis-like skin inflammation in mice is mediated via the IL-23/IL-17 axis. J Immunol. 2009;182:5836–45.

Article  PubMed  Google Scholar 

Mehta H, Mashiko S, Angsana J, Rubio M, Hsieh Y-CM, Maari C, Reich K, Blauvelt A, Bissonnette R. Muñoz-Elías, Differential changes in inflammatory mononuclear phagocyte and T-cell profiles within psoriatic skin during treatment with guselkumab vs. secukinumab. J Invest Dermatology. 2021;141:1707–18. e9.

Article  CAS  Google Scholar 

Chiricozzi A, Krueger JG. IL-17 targeted therapies for psoriasis. Expert Opin Investig Drugs. 2013;22:993–1005.

Article  CAS  PubMed  Google Scholar 

Kanda N, Hoashi T, Saeki H. The defect in regulatory T cells in psoriasis and therapeutic approaches. J Clin Med. 2021;10:3880.

Article  CAS  PubMed  PubMed Central  Google Scholar 

Nussbaum L, Chen YL, Ogg GS. Role of regulatory T cells in psoriasis pathogenesis and treatment. Br J Dermatol. 2021;184:14–24.

Article  CAS  PubMed  Google Scholar 

Mattozzi C, Salvi M, D’epiro S, Giancristoforo S, Macaluso L, Luci C, Lal K, Calvieri S, Richetta AG. Importance of regulatory T cells in the pathogenesis of psoriasis: review of the literature. Dermatology. 2013;227:134–45.

Article  CAS  PubMed  Google Scholar 

Martin DA, Towne JE, Kricorian G, Klekotka P, Gudjonsson JE, Krueger JG, Russell CB. The emerging role of IL-17 in the pathogenesis of psoriasis: preclinical and clinical findings. J Invest Dermatology. 2013;133:17–26.

Article  CAS  Google Scholar 

Krueger JG, Krane JF, Carter DM, Gottlieb AB. Role of growth factors, cytokines, and their receptors in the pathogenesis of psoriasis. J Invest Dermatology. 1990;94:s135–40.

Article  Google Scholar 

Moustou AE, Alexandrou P, Stratigos AJ, Giannopoulou I, Vergou T, Katsambas A, Antoniou C. Expression of lymphatic markers and lymphatic growth factors in psoriasis before and after anti-TNF treatment. An Bras Dermatol. 2014;89:891–7.

Article  PubMed  PubMed Central  Google Scholar 

Ren K, Xia Y. Lipocalin 2 participates in the epidermal differentiation and inflammatory processes of psoriasis. J Inflamm Res (2022) 2157–66.

Mavropoulos A, Rigopoulou EI, Liaskos C, Bogdanos DP, Sakkas LI. The role of p38 MAPK in the aetiopathogenesis of psoriasis and psoriatic arthritis, Journal of Immunology Research 2013 (2013).

Pervizaj-Oruqaj L, Selvakumar B, Ferrero MR, Heiner M, Malainou C, Glaser RD, Wilhelm J, Bartkuhn M, Weiss A, Alexopoulos I. Alveolar macrophage-expressed Plet1 is a driver of lung epithelial repair after viral pneumonia. Nat Commun. 2024;15:87.

Article  CAS  PubMed  PubMed Central  Google Scholar 

Kurasawa K, Hirose K, Sano H, Endo H, Shinkai H, Nawata Y, Takabayashi K, Iwamoto I. Increased interleukin-17 production in patients with systemic sclerosis. Arthritis Rheumatism: Official J Am Coll Rheumatol. 2000;43:2455–63.

Article  CAS  Google Scholar