Su G, Zhang Y, Xiao R, Zhang T, Gong B. Systemic immune-inflammation index as a promising predictor of mortality in patients with acute coronary syndrome: a real-world study. J Int Med Res. 2021;49:3000605211016274.

Article  CAS  PubMed  Google Scholar 

Teo KK, Rafiq T. Cardiovascular Risk factors and Prevention: a perspective from developing countries. Can J Cardiol. 2021;37:733–43.

Article  PubMed  Google Scholar 

Centers for Disease Control and Prevention. National Cancer Statistics Report, 2016–20.

Torre LA, Siegel RL, Ward EM, Jemal A. Global Cancer Incidence and Mortality Rates and Trends–An Update. Cancer epidemiology, biomarkers & prevention: a publication of the American Association for Cancer Research. Cosponsored Am Soc Prev Oncol. 2016;25:16–27.

Google Scholar 

Yang YL, Wu CH, Hsu PF, Chen SC, Huang SS, Chan WL, et al. Systemic immune-inflammation index (SII) predicted clinical outcome in patients with coronary artery disease. Eur J Clin Invest. 2020;50:e13230.

Article  CAS  PubMed  Google Scholar 

Karimi A, Shobeiri P, Kulasinghe A, Rezaei N. Novel systemic inflammation markers to Predict COVID-19 prognosis. Front Immunol. 2021;12:741061.

Article  CAS  PubMed  PubMed Central  Google Scholar 

Zhang K, Hua YQ, Wang D, Chen LY, Wu CJ, Chen Z, et al. Systemic immune-inflammation index predicts prognosis of patients with advanced pancreatic cancer. J Translational Med. 2019;17:30.

Article  Google Scholar 

Candemir M, Kiziltunç E, Nurkoç S, Şahinarslan A. Relationship between systemic Immune-inflammation index (SII) and the severity of stable coronary artery disease. Angiology. 2021;72:575–81.

Article  CAS  PubMed  Google Scholar 

Wang H, Nie H, Bu G, Tong X, Bai X. Systemic immune-inflammation index (SII) and the risk of all-cause, cardiovascular, and cardio-cerebrovascular mortality in the general population. Eur J Med Res. 2023;28:575.

Article  CAS  PubMed  PubMed Central  Google Scholar 

Xiao S, Wang Z, Zuo R, Zhou Y, Yang Y, Chen T, et al. Association of systemic Immune inflammation index with All-Cause, Cardiovascular Disease, and Cancer-related mortality in patients with Cardiovascular Disease: a cross-sectional study. J Inflamm Res. 2023;16:941–61.

Article  CAS  PubMed  PubMed Central  Google Scholar 

Qu L, Zuo X, Yu J, Duan R, Zhao B. Association of inflammatory markers with all-cause mortality and cardiovascular mortality in postmenopausal women with osteoporosis or osteopenia. BMC Womens Health. 2023;23:487.

Article  CAS  PubMed  PubMed Central  Google Scholar 

Cao Y, Li P, Zhang Y, Qiu M, Li J, Ma S, et al. Association of systemic immune inflammatory index with all-cause and cause-specific mortality in hypertensive individuals: results from NHANES. Front Immunol. 2023;14:1087345.

Article  CAS  PubMed  PubMed Central  Google Scholar 

Li H, Wu X, Bai Y, Wei W, Li G, Fu M, et al. Physical activity attenuates the associations of systemic immune-inflammation index with total and cause-specific mortality among middle-aged and older populations. Sci Rep. 2021;11:12532.

Article  CAS  PubMed  PubMed Central  Google Scholar 

Zheng Z, Luo H, Xue Q. U-shaped association of systemic immune-inflammation index levels with cancer-related and all-cause mortality in middle-aged and older individuals with frailty. Arch Gerontol Geriatr 2024; 116.

Chen C, Chen Y, Gao Q, Wei Q. Association of systemic immune inflammatory index with all-cause and cause-specific mortality among individuals with type 2 diabetes. BMC Cardiovasc Disord. 2023;23:596.

Article  CAS  PubMed  PubMed Central  Google Scholar 

Yang C, Yang Q, Xie Z, Peng X, Liu H, Xie C. Association of systemic immune-inflammation-index with all-cause and cause-specific mortality among type 2 diabetes: a cohort study base on population. Endocrine 2023.

Xia Y, Xia C, Wu L, Li Z, Li H, Zhang J. Systemic Immune inflammation index (SII), system inflammation response index (SIRI) and risk of all-cause Mortality and Cardiovascular Mortality: a 20-Year Follow-Up Cohort Study of 42,875 US adults. J Clin Med 2023; 12.

Kong F, Huang J, Xu C, Huang T, Wen G, Cheng W. System inflammation response index: a novel inflammatory indicator to predict all-cause and cardiovascular disease mortality in the obese population. Diabetol Metab Syndr. 2023;15:195.

Article  CAS  PubMed  PubMed Central  Google Scholar 

Li G, Yu J, Jiang S, Wu K, Xu Y, Lu X, et al. Systemic Immune-inflammation index was significantly Associated with all-cause and Cardiovascular-Specific mortalities in patients receiving peritoneal Dialysis. J Inflamm Res. 2023;16:3871–8.

Article  CAS  PubMed  PubMed Central  Google Scholar 

Xie M, Yuan K, Zhu X, Chen J, Zhang X, Xie Y, et al. Systemic Immune-inflammation index and long-term mortality in patients with Stroke-Associated Pneumonia. J Inflamm Res. 2023;16:1581–93.

Article  CAS  PubMed  PubMed Central  Google Scholar 

Meng C, Liu K. Nonlinear association of the systemic immune-inflammatory index with mortality in diabetic patients. Front Endocrinol. 2024;15:1334811.

Article  Google Scholar 

Hayıroğlu M, Çınar T, Çinier G, Pay L, Yumurtaş A, Tezen O, et al. Evaluating systemic immune-inflammation index in patients with implantable cardioverter defibrillator for heart failure with reduced ejection fraction. Pacing Clin Electrophysiology: PACE. 2022;45:188–95.

Article  Google Scholar 

Peng Y, Huang W, Shi Z, Chen Y, Ma J. Positive association between systemic immune-inflammatory index and mortality of cardiogenic shock. Clin Chim Acta. 2020;511:97–103.

Article  CAS  PubMed  Google Scholar 

Jin Z, Wu Q, Chen S, Gao J, Li X, Zhang X, et al. The associations of two novel inflammation indexes, SII and SIRI with the risks for Cardiovascular diseases and all-cause mortality: a ten-year Follow-Up study in 85,154 individuals. J Inflamm Res. 2021;14:131–40.

Article  PubMed  PubMed Central  Google Scholar 

Benz E, Wijnant SRA, Trajanoska K, Arinze JT, de Roos EW, de Ridder M et al. Sarcopenia, systemic immune-inflammation index and all-cause mortality in middle-aged and older people with COPD and asthma: a population-based study. ERJ open Res 2022; 8.

Jiang D, Bian T, Shen Y, Huang Z. Association between admission systemic immune-inflammation index and mortality in critically ill patients with sepsis: a retrospective cohort study based on MIMIC-IV database. Clin Experimental Med. 2023;23:3641–50.

Article  CAS  Google Scholar 

Keskin M, Öcal L, Cerşit S, Yılmaz C, Küp A, Çelik M, et al. The predictive role of a novel risk index in patients undergoing carotid artery stenting: systemic Immune-inflammation index. J Stroke Cerebrovasc Diseases: Official J Natl Stroke Association. 2021;30:105955.

Article  Google Scholar 

Yuan M, Ren F, Gao D. The Value of SII in Predicting the Mortality of Patients with Heart Failure. Disease markers. 2022; 2022:3455372.

Kudlinski B, Zgoła D, Stolińska M, Murkos M, Kania J, Nowak P et al. Systemic Inflammatory Predictors of In-Hospital Mortality in COVID-19 Patients: A Retrospective Study. Diagnostics (Basel, Switzerland). 2022; 12.

Wang Z, Ruan H, Li L, Wei X, Zhu Y, Wei J et al. Assessing the relationship between systemic immune-inflammation index and mortality in patients with hypertrophic cardiomyopathy. Ups J Med Sci 2021; 126.

Zhao J, Lv H, Yin D, Zhou X, Zhu H, Guo L, et al. Systemic Immune-inflammation index predicts long-term outcomes in patients with three-vessel coronary disease after revascularization: results from a large cohort of 3561 patients. J Inflamm Res. 2022;15:5283–92.

Article  PubMed  PubMed Central  Google Scholar 

Wu S, Shi X, Zhou Q, Duan X, Zhang X, Guo H. The Association between Systemic Immune-Inflammation Index and All-Cause Mortality in Acute Ischemic Stroke Patients: Analysis from the MIMIC-IV Database. Emergency medicine international. 2022; 2022:4156489.

Huang J, Zhang Q, Wang R, Ji H, Chen Y, Quan X, et al. Systemic Immune-Inflammatory Index predicts clinical outcomes for Elderly patients with Acute Myocardial Infarction receiving percutaneous coronary intervention. Med Sci Monitor: Int Med J Experimental Clin Res. 2019;25:9690–701.

Article  Google Scholar 

Zhang D, Wang T, Dong X, Sun L, Wu Q, Liu J, et al. Systemic Immune-inflammation index for Predicting the prognosis of critically ill patients with Acute Pancreatitis. Int J Gen Med. 2021;14:4491–8.

Article  PubMed  PubMed Central  Google Scholar 

Yang Y, Xu Y, Liu S, Lu P, Zhou H, Yang M. The systemic inflammation indexes predict all-cause mortality in peritoneal dialysis patients. Ren Fail. 2023;45:2160348.

Article  PubMed  PubMed Central  Google Scholar 

Jia L, Li C, Bi X, Wei F, Meng J, Sun G et al. Prognostic value of systemic Immune-inflammation index among critically ill patients with acute kidney Injury: a retrospective cohort study. J Clin Med 2022; 11.

Çavuşoğlu Türker B, Ahbab S, Türker F, Hoca E, Çiftçi Öztürk E, Kula AC, et al. Systemic Immune-inflammation and systemic inflammation response indices are predictive markers of Mortality in Inpatients Internal Medicine Services. Int J Gen Med. 2023;16:3163–70.

Article  PubMed  PubMed Central  Google Scholar 

He L, Xie X, Xue J, Xie H, Zhang Y. Association of the systemic immune-inflammation index with all-cause mortality in patients with arteriosclerotic cardiovascular disease. Front Cardiovasc Med. 2022;9:952953.

Article  CAS  PubMed  PubMed Central  Google Scholar 

Zhao E, Cheng Y, Yu C, Li H, Fan X. The systemic immune-inflammation index was non-linear associated with all-cause mortality in individuals with nonalcoholic fatty liver disease. Ann Med. 2023;55:2197652.