Li Z-M, Xu S-W, Liu P-Q. Salvia miltiorrhizaBurge (Danshen): a golden herbal medicine in cardiovascular therapeutics. Acta Pharmacol Sin. 2018;39(5):802–24.
Article CAS PubMed PubMed Central Google Scholar
Liu C, Zhang L, Li Y, Li M, Han H, Wang K. Traditional Chinese patent medicine in the treatment of Alzheimer’s disease: a systematic review and network meta-analysis. Am J Chin Med. 2023;51(03):517–46.
Article CAS PubMed Google Scholar
Yang L, Liu X, Zhu J, Zhang X, Li Y, Chen J, Liu H. Progress in traditional Chinese medicine against chronic gastritis: from chronic non-atrophic gastritis to gastric precancerous lesions. Heliyon. 2023. https://doi.org/10.1016/j.heliyon.2023.e16764.
Article PubMed PubMed Central Google Scholar
Ai C, Zou Y, Liu H, Yang Z, Xi J. Traditional Chinese herbal medicine for allergic diseases: a review. Am J Chin Med. 2023;51(04):779–806.
Article CAS PubMed Google Scholar
Gonzalez-Munoz AL, Minter RR, Rust SJ. Phenotypic screening: the future of antibody discovery. Drug Discov Today. 2016;21(1):150–6.
Article CAS PubMed Google Scholar
Swinney DC. Phenotypic vs. Target-based drug discovery for first-in-class medicines. Clin Pharmacol Ther. 2013;93(4):299–301.
Article CAS PubMed Google Scholar
Sang Z, Wang K, Dong J, Tang L. Alzheimer’s disease: updated multi-targets therapeutics are in clinical and in progress. Eur J Med Chem. 2022. https://doi.org/10.1016/j.ejmech.2022.114464.
Vincent F, Nueda A, Lee J, Schenone M, Prunotto M, Mercola M. Phenotypic drug discovery: recent successes, lessons learned and new directions. Nat Rev Drug Discov. 2022;21(12):899–914.
Article CAS PubMed PubMed Central Google Scholar
Berg EL. The future of phenotypic drug discovery. Cell Chem Biol. 2021;28(3):424–30.
Article CAS PubMed Google Scholar
Swinney DC, Anthony J. How were new medicines discovered? Nat Rev Drug Discov. 2011;10(7):507–19.
Article CAS PubMed Google Scholar
Wu Y, Zhang F, Yang K, Fang S, Bu D, Li H, Sun L, Hu H, Gao K, Wang W, Zhou X, Zhao Y, Chen J. SymMap: an integrative database of traditional Chinese medicine enhanced by symptom mapping. Nucleic Acids Res. 2019;47(D1):D1110–7.
Harvey AL, Edrada-Ebel R, Quinn RJ. The re-emergence of natural products for drug discovery in the genomics era. Nat Rev Drug Discov. 2015;14(2):111–29.
Article CAS PubMed Google Scholar
Atanasov AG, Zotchev SB, Dirsch VM, Supuran CT. Natural products in drug discovery: advances and opportunities. Nat Rev Drug Discov. 2021;20(3):200–16.
Article CAS PubMed PubMed Central Google Scholar
Feng X, Li Y, Wang Y, Li L, Little PJ, Xu S-W, Liu S. Danhong injection in cardiovascular and cerebrovascular diseases: pharmacological actions, molecular mechanisms, and therapeutic potential. Pharmacol Res. 2019;139:62–75.
Article CAS PubMed Google Scholar
Orgah JO, He S, Wang Y, Jiang M, Wang Y, Orgah EA, Duan Y, Zhao B, Zhang B, Han J, Zhu Y. Pharmacological potential of the combination of Salvia miltiorrhiza (Danshen) and Carthamus tinctorius (Honghua) for diabetes mellitus and its cardiovascular complications. Pharmacol Res. 2020. https://doi.org/10.1016/j.phrs.2020.104654.
Mao H-P, Wang X-Y, Gao YH, Chang Y-X, Chen L, Niu Z-C, Ai J-Q, Gao X-M. Danhong injection attenuates isoproterenol-induced cardiac hypertrophy by regulating p38 and NF-κb pathway. J Ethnopharmacol. 2016;186:20–9.
Article CAS PubMed Google Scholar
Zhang X, Ma Z-G, Yuan Y-P, Xu S-C, Wei W-Y, Song P, Kong C-Y, Deng W, Tang Q-Z. Rosmarinic acid attenuates cardiac fibrosis following long-term pressure overload via AMPKα/Smad3 signaling. Cell Death Dis. 2018. https://doi.org/10.1038/s41419-017-0123-3.
Article PubMed PubMed Central Google Scholar
Zhong W, Sun B, Gao W, Qin Y, Zhang H, Huai L, Tang Y, Liang Y, He L, Zhang X, Tao H, Chen S, Yang W, Yang L, Liu Y, Liu H, Zhou H, Sun T, Yang C. Salvianolic acid A targeting the transgelin-actin complex to enhance vasoconstriction. EBioMedicine. 2018;37:246–58.
Article PubMed PubMed Central Google Scholar
Hopkins AL. Network pharmacology: the next paradigm in drug discovery. Nat Chem Biol. 2008;4(11):682–90.
Article CAS PubMed Google Scholar
Ball KA, Webb KJ, Coleman SJ, Cozzolino KA, Jacobsen J, Jones KR, Stowell MHB, Old WM. An isothermal shift assay for proteome scale drug-target identification. Commun Biol. 2020. https://doi.org/10.1038/s42003-020-0795-6.
Article PubMed PubMed Central Google Scholar
Martinez Molina D, Jafari R, Ignatushchenko M, Seki T, Larsson EA, Dan C, Sreekumar L, Cao Y, Nordlund P. Monitoring drug target engagement in cells and tissues using the cellular thermal shift assay. Science. 2013;341(6141):84–7.
Wang T, Yang C, Li Z, Li T, Zhang R, Zhao Y, Cheng T, Zong Z, Ma Y, Zhang D, Deng H. Flavonoid 4,4′-dimethoxychalcone selectively eliminates senescent cells via activating ferritinophagy. Redox Biol. 2024. https://doi.org/10.1016/j.redox.2023.103017.
Article PubMed PubMed Central Google Scholar
Ashburner M, Ball CA, Blake JA, Botstein D, Heather Butler J, Cherry M, Davis AP, Dolinski K, Dwight SS, Eppig JT, Harris MA, Hill DP, Issel-Tarver L, Kasarskis A, Lewis S, Matese JC, Richardson JE, Ringwald M, Rubin GM, Sherlock G. Gene ontology: tool for the unification of biology. The gene ontology consortium. Nat Genet. 2000;25(1):25–9.
Article CAS PubMed PubMed Central Google Scholar
Kanehisa M, Goto S. KEGG: kyoto encyclopedia of genes and genomes. Nucleic Acids Res. 2000;28(1):27–30.
Article CAS PubMed PubMed Central Google Scholar
Stelzer G, Rosen N, Plaschkes I, Zimmerman S, Twik M, Fishilevich S, Stein TI, Nudel R, Lieder I, Mazor Y, Kaplan S, Dahary D, Warshawsky D, Guan-Golan Y, Kohn A, Rappaport N, Safran M, Lancet D. The GeneCards suite: from gene data mining to disease genome sequence analyses. Curr Protoc Bioinform. 2016. https://doi.org/10.1002/cpbi.5.
Knox C, Wilson M, Klinger CM, Franklin M, Oler E, Wilson A, Pon A, Cox J, Chin NE, Strawbridge SA, Garcia-Patino M, Kruger R, Sivakumaran A, Sanford S, Doshi R, Khetarpal N, Fatokun O, Doucet D, Zubkowski A, Rayat DY, Jackson H, Harford K, Anjum A, Zakir M, Wang F, Tian S, Lee B, Liigand J, Peters H, Wang RQ, Nguyen T, So D, Sharp M, da Silva R, Gabriel C, Scantlebury J, Jasinski M, Ackerman D, Jewison T, Sajed T, Gautam V, Wishart DS. DrugBank 6.0: the DrugBank knowledgebase for 2024. Nucleic Acids Res. 2024;52(D1):D1265–75.
Whirl-Carrillo M, McDonagh EM, Hebert JM, Gong L, Sangkuhl K, Thorn CF, Altman RB, Klein TE. Pharmacogenomics knowledge for personalized medicine. Clin Pharmacol Ther. 2012;92(4):414–7.
Article CAS PubMed Google Scholar
Bateman A, Martin M-J, Orchard S, Magrane M, Ahmad S, Alpi E, Bowler-Barnett EH, Britto R, Bye-A-Jee H, Cukura A, Denny P, Dogan T, Ebenezer T, Fan J, Garmiri P, da Costa Gonzales LJ, Hatton-Ellis E, Hussein A, Ignatchenko A, Insana G, Ishtiaq R, Joshi V, Jyothi D, Kandasaamy S, Lock A, Luciani A, Lugaric M, Luo J, Lussi Y, MacDougall A, Madeira F, Mahmoudy M, Mishra A, Moulang K, Nightingale A, Pundir S, Qi G, Raj S, Raposo P, Rice DL, Saidi R, Santos R, Speretta E, Stephenson J, Totoo P, Turner E, Tyagi N, Vasudev P, Warner K, Watkins X, Zaru R, Zellner H, Bridge AJ, Aimo L, Argoud-Puy G, Auchincloss AH, Axelsen KB, Bansal P, Baratin D, Batista Neto TM, Blatter M-C, Bolleman JT, Boutet E, Breuza L, Gil BC, Casals-Casas C, Echioukh KC, Coudert E, Cuche B, de Castro E, Estreicher A, Famiglietti ML, Feuermann M, Gasteiger E, Gaudet P, Gehant S, Gerritsen V, Gos A, Gruaz N, Hulo C, Hyka-Nouspikel N, Jungo F, Kerhornou A, Le Mercier P, Lieberherr D, Masson P, Morgat A, Muthukrishnan V, Paesano S, Pedruzzi I, Pilbout S, Pourcel L, Poux S, Pozzato M, Pruess M, Redaschi N, Rivoire C, Sigrist CJA, Sonesson K, Sundaram S, Wu CH, Arighi CN, Arminski L, Chen C, Chen Y, Huang H, Laiho K, McGarvey P, Natale DA, Ross K, Vinayaka CR, Wang Q, Wang Y, Zhang J. UniProt: the universal protein knowledgebase in 2023. Nucleic Acids Res. 2023;51(D1):D523–31.
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