SPLASH study group: Julio Abba MD1, Irchid Al-naasan16, Charles Aarteaga10, Sandrine Barbois1, Thierry Bege15, Jean-Paul Bergi2, Matthieu Biais3, Guillaume Bouhours4, Antoine Bouvier4,  Jean-Luc Bosson1, Pierre Bouzat1, Katia Chaumoitre15, Jonathan Charbit6, Raphael Cinotti7, Philippe Cluzel8, Philippe Compagnon14, François Cotton5 , Myriam Coutard1,  Jean Louis Daban13, Charles Daragon11, Jean-Stéphane David5, Frederic Douane7, Vincent Dubuisson3, Anne Ego1, Patrice Fernandez12, Julien Frandon2, Delphine Garrigue9, Julien Guelfi1, Françoise Guillon6, Marc Haberlay9, Hassen Hentati14 , Christophe Henry12, Emmanuel Hornez13, Hicham Kobeiter14, Nicolas Huet1, Yann Lebras3, Marie-Christine LEMOINE2, Marc Leone15,  Emilie Lermite4, Nathalie Lesavre15, Albrice Levrat11, Thomas Martinilli12, Eric Meaudre13, Jean-Philippe Mestrallet11, Sylvie Metairie7, Marie Michoud16, Tristan Monchal10, Valérie Monnin-Bares6, Laurent Muller2, Jean-Robert Nzamushe9, Guillaume Passot5, Julien Picard1, Isabelle Plenier9, Bertrand Prunet10, Mathieu Raux8, Catherine Ridereau4, Mathieu Rodiere1, Christophe Teriitehau13, Melanie Terebus-loock16, Jean-Marc Thouret16, Frédéric Thony1, Christophe Tresallet8, Pierre-Jean Valette5,  Antoine Vilotitch1, Eric Voiglio5.  University Hospitals (CHU) at 1 Grenoble Alpes,2 Nîmes, 3 Bordeaux, 4Angers, 5Lyon Sud, 6 Montpellier, 7Nantes, 8 Pitié-Salpêtrière, Paris, 14 Henri-Mondor, Créteil, 15Nord Marseille; Hospitals (CH), 11Annecy-Genevois, 12 Valence, 16 Chambéry, 9 Regional University Hospital (CHRU) Lille, and Army Teaching Hospital (HIA) 13Percy, and 10Sainte-Anne, Toulon.