McDonagh TA, Metra M, Adamo M, Gardner RS, Baumbach A, Böhm M, Burri H, Butler J, Čelutkienė J, Chioncel O, Cleland JGF, Coats AJS, Crespo-Leiro MG, Farmakis D, Gilard M, Heymans S, Hoes AW, Jaarsma T, Jankowska EA, Lainscak M, ESC Scientific Document Group. 2021 ESC Guidelines for the diagnosis and treatment of acute and chronic heart failure. Eur Heart J. 2021;42(36):3599–726. https://doi.org/10.1093/eurheartj/ehab368.

Article  CAS  PubMed  Google Scholar 

Zhang YN, Vernooij F, Ibrahim I, Ooi S, Gijsberts CM, Schoneveld AH, Sen KW, den Ruijter HM, Timmers L, Richards AM, Jong CT, Mazlan I, Wang JW, Lam CS, de Kleijn DP. Extracellular vesicle proteins associated with systemic vascular events correlate with heart failure: an observational study in a dyspnoea cohort. PLoS ONE. 2016;11(1):e0148073. https://doi.org/10.1371/journal.pone.0148073.

Article  CAS  PubMed  PubMed Central  Google Scholar 

Zgutka K, Tkacz M, Tomasiak P, Tarnowski M. A role for advanced glycation end products in molecular ageing. Int J Mol Sci. 2023;24(12):9881. https://doi.org/10.3390/ijms24129881.

Article  CAS  PubMed  PubMed Central  Google Scholar 

Zeng C, Li Y, Ma J, Niu L, Tay FR. Clinical/translational aspects of advanced glycation end-products. Trends Endocrinol Metab. 2019;30(12):959–73. https://doi.org/10.1016/j.tem.2019.08.005.

Article  CAS  PubMed  Google Scholar 

Smit AJ, Hartog JW, Voors AA, van Veldhuisen DJ. Advanced glycation endproducts in chronic heart failure. Ann N Y Acad Sci. 2008;1126:225–30. https://doi.org/10.1196/annals.1433.038.

Article  CAS  PubMed  Google Scholar 

Bidasee KR, Zhang Y, Shao CH, Wang M, Patel KP, Dincer UD, Besch HR Jr. Diabetes increases formation of advanced glycation end products on Sarco(endo)plasmic reticulum Ca2+-ATPase. Diabetes. 2004;53(2):463–73. https://doi.org/10.2337/diabetes.53.2.463.

Article  CAS  PubMed  Google Scholar 

Hartog JW, Voors AA, Bakker SJ, Smit AJ, van Veldhuisen DJ. Advanced glycation end-products (AGEs) and heart failure: pathophysiology and clinical implications. Eur J Heart Fail. 2007;9(12):1146–55. https://doi.org/10.1016/j.ejheart.2007.09.009.

Article  CAS  PubMed  Google Scholar 

van Niel G, D’Angelo G, Raposo G. Shedding light on the cell biology of extracellular vesicles. Nat Rev Mol Cell Biol. 2018;19(4):213–28. https://doi.org/10.1038/nrm.2017.125.

Article  CAS  PubMed  Google Scholar 

Gasecka A, Nieuwland R, Budnik M, Dignat-George F, Eyileten C, Harrison P, Huczek Z, Kapłon-Cieślicka A, Lacroix R, Opolski G, Pluta K, van der Pol E, Postuła M, Leroyer A, Siljander P, Sturk A, Filipiak KJ. Randomized controlled trial protocol to investigate the antiplatelet therapy effect on extracellular vesicles (AFFECT EV) in acute myocardial infarction. Platelets. 2020;31(1):26–32. https://doi.org/10.1080/09537104.2018.1557616.

Article  CAS  PubMed  Google Scholar 

Gąsecka A, Pluta K, Solarska K, Rydz B, Eyileten C, Postula M, van der Pol E, Nieuwland R, Budnik M, Kochanowski J, Jaguszewski MJ, Szarpak Ł, Mazurek T, Kapłon-Cieślicka A, Opolski G, Filipiak KJ. Plasma concentrations of extracellular vesicles are decreased in patients with post-infarct cardiac remodelling. Biology. 2021;10(2):97. https://doi.org/10.3390/biology10020097.

Article  CAS  PubMed  PubMed Central  Google Scholar 

Berezin AE, Kremzer AA, Martovitskaya YV, Berezina TA, Gromenko EA. Pattern of endothelial progenitor cells and apoptotic endothelial cell-derived microparticles in chronic heart failure patients with preserved and reduced left ventricular ejection fraction. EBioMedicine. 2016;4:86–94. https://doi.org/10.1016/j.ebiom.2016.01.018.

Article  PubMed  PubMed Central  Google Scholar 

Nagueh SF, Smiseth OA, Appleton CP, Byrd BF 3rd, Dokainish H, Edvardsen T, Flachskampf FA, Gillebert TC, Klein AL, Lancellotti P, Marino P, Oh JK, Popescu BA, Waggoner AD. Recommendations for the evaluation of left ventricular diastolic function by echocardiography: an update from the American Society of Echocardiography and the European Association of Cardiovascular Imaging. J American Soc Echocardiogr: Off Publ Am Soc Echocardiogr. 2016;29(4):277–314. https://doi.org/10.1016/j.echo.2016.01.011.

Article  Google Scholar 

Rolek B, Błażejowska E, Procyk G, Zimodro JM, Gąsecka A. Dedicated devices for non-invasive cardiovascular risk assessment - the future of cardiovascular prevention. Cardiol J. 2024;31(3):496–8. https://doi.org/10.5603/cj.96477.

Article  PubMed  PubMed Central  Google Scholar 

Coumans FAW, Brisson AR, Buzas EI, Dignat-George F, Drees EEE, El-Andaloussi S, Emanueli C, Gasecka A, Hendrix A, Hill AF, Lacroix R, Lee Y, van Leeuwen TG, Mackman N, Mäger I, Nolan JP, van der Pol E, Pegtel DM, Sahoo S, Siljander PRM, Nieuwland R. Methodological guidelines to study extracellular vesicles. Circ Res. 2017;120(10):1632–48. https://doi.org/10.1161/CIRCRESAHA.117.309417.

Article  CAS  PubMed  Google Scholar 

Welsh JA, Van Der Pol E, Arkesteijn GJA, Bremer M, Brisson A, Coumans F, Dignat-George F, Duggan E, Ghiran I, Giebel B, Görgens A, Hendrix A, Lacroix R, Lannigan J, Libregts SFWM, Lozano-Andrés E, Morales-Kastresana A, Robert S, De Rond L, Tertel T, Jones JC. MIFlowCyt-EV: a framework for standardized reporting of extracellular vesicle flow cytometry experiments. J Extracellular Vesicles. 2020;9(1):1713526. https://doi.org/10.1080/20013078.2020.1713526.

Article  CAS  Google Scholar 

Vilella-Figuerola A, Padró T, Roig E, Mirabet S, Badimon L. New factors in heart failure pathophysiology: Immunity cells release of extracellular vesicles. Front Cardiovasc Med. 2022;9:939625. https://doi.org/10.3389/fcvm.2022.939625.

Article  CAS  PubMed  PubMed Central  Google Scholar 

Kain V, Halade GV. Role of neutrophils in ischemic heart failure. Pharmacol Ther. 2020;205:107424. https://doi.org/10.1016/j.pharmthera.2019.107424.

Article  CAS  PubMed  Google Scholar 

Altamura M, D’Andrea G, Angelini E, Tortorelli FMP, Balzotti A, Porcelli P, Margaglione M, Brunetti ND, Cassano T, Bellomo A. Psychosomatic syndromes are associated with IL-6 pro-inflammatory cytokine in heart failure patients. PLoS ONE. 2022;17(3):e0265282. https://doi.org/10.1371/journal.pone.0265282.

Article  CAS  PubMed  PubMed Central  Google Scholar 

Li X, Zeng L, Qu Z, Zhang F. Huoxin pill protects verapamil-induced zebrafish heart failure through inhibition of oxidative stress-triggered inflammation and apoptosis. Heliyon. 2023;10(1):e23402. https://doi.org/10.1016/j.heliyon.2023.e23402.

Article  CAS  PubMed  PubMed Central  Google Scholar 

Sarlon-Bartoli G, Bennis Y, Lacroix R, Piercecchi-Marti MD, Bartoli MA, Arnaud L, Mancini J, Boudes A, Sarlon E, Thevenin B, Leroyer AS, Squarcioni C, Magnan PE, Dignat-George F, Sabatier F. Plasmatic level of leukocyte-derived microparticles is associated with unstable plaque in asymptomatic patients with high-grade carotid stenosis. J Am Coll Cardiol. 2013;62(16):1436–41. https://doi.org/10.1016/j.jacc.2013.03.078.

Article  CAS  PubMed  Google Scholar 

Chironi G, Simon A, Hugel B, Del Pino M, Gariepy J, Freyssinet JM, Tedgui A. Circulating leukocyte-derived microparticles predict subclinical atherosclerosis burden in asymptomatic subjects. Arterioscler Thromb Vasc Biol. 2006;26(12):2775–80. https://doi.org/10.1161/01.ATV.0000249639.36915.04.

Article  CAS  PubMed  Google Scholar 

Kou Y, Zou L, Liu R, Zhao X, Wang Y, Zhang C, Dong Z, Kou J, Bi Y, Fu L, Shi J. Intravascular cells and circulating microparticles induce procoagulant activity via phosphatidylserine exposure in heart failure. J Thromb Thrombolysis. 2019;48(2):187–94. https://doi.org/10.1007/s11239-019-01889-8.

Article  CAS  PubMed  Google Scholar 

Vilella-Figuerola A, Cordero A, Mirabet S, Muñoz-García N, Suades R, Padró T, Badimon L. Platelet-Released Extracellular Vesicle Characteristics Differ in Chronic and in Acute Heart Disease. Thromb Haemost. 2023;123(9):892–903. https://doi.org/10.1055/s-0043-57017.

Article  PubMed  Google Scholar 

Tripisciano C, Weiss R, Eichhorn T, Spittler A, Heuser T, Fischer MB, Weber V. Different Potential of Extracellular Vesicles to Support Thrombin Generation: Contributions of Phosphatidylserine, Tissue Factor, and Cellular Origin. Sci Rep. 2017;7(1):6522. https://doi.org/10.1038/s41598-017-03262-2.

Article  CAS  PubMed  PubMed Central  Google Scholar 

Bettin B, Gasecka A, Li B, Dhondt B, Hendrix A, Nieuwland R, van der Pol E. Removal of platelets from blood plasma to improve the quality of extracellular vesicle research. J Thromb Haemost: JTH. 2022;20(11):2679–85. https://doi.org/10.1111/jth.15867.