Exploring of biological activity and diverse metabolites in hemp (Cannabis sativa) seed oil by GC/MS, GC–FID, and LC–HRMS chromatographies

Skrovankova S, Ladislava M, Ludmila M (2012) Antioxidant activity and protecting health effects of common medicinal plants. Adv Food Nutr Res 67:75–139

Article  CAS  PubMed  Google Scholar 

Kiziltas H, Bingol Z, Goren AC, Alwasel SH, Gulcin I (2021) Anticholinergic, antidiabetic and antioxidant activities of Ferula orientalis L.-analysis of its polyphenol contents by LC-HRMS. Rec Nat Prod 15(6):513–528

Article  CAS  Google Scholar 

Cavazos P, David G, Jocelyn L, Ruby Y (2021) Secondary metabolites, antibacterial and antioxidant properties of the leaf extracts of Acacia rigidula benth. and Acacia berlandieri benth. SN Appl Sci 3:1–14

Article  Google Scholar 

Gulcin I (2020) Antioxidants and antioxidant methods: an updated overview. Arch Toxicol 94(3):651–715

Article  CAS  PubMed  Google Scholar 

Somogyi A, Klara R, Peter P, Zsolt T, Geza N (2007) Antioxidant measurements. Physiol Measure 28:R41

Article  Google Scholar 

Topal F, Topal M, Gocer H, Kalın P, Koçyiğit UM, Gulcin I, Alwasel SH (2016) Antioxidant activity of taxifolin: an activity-structure relationship. J Enzyme Inhib Med Chem 31(4):674–683

Article  CAS  PubMed  Google Scholar 

Gülcin I (2012) Antioxidant activity of food constituents: an overview. Arch Toxicol 86:345–391

Article  PubMed  Google Scholar 

Semwogerere F, Obert CC, Chenaimoyo LFK, Munyaradzi CM, Cletos M (2023) Bioavailability of bioactive phytochemicals in selected tissues and excreta from goats fed hempseed cake (Cannabis sativa L.) finisher diets. Trop Anim Health Prod 55(4):262

Article  PubMed  PubMed Central  Google Scholar 

Frassinetti S, Eleonora M, Leonardo C, Morena G, Vincenzo L, Lorenza B, Gianluca G, Lucia G (2018) Nutraceutical potential of hemp (Cannabis sativa L.) seeds and sprouts. Food Chem 262:56–66

Article  CAS  PubMed  Google Scholar 

Saint Jalmes M, Fedyashov V, Beck D, Baldwin T, Faux NG, Bourgeat P, Fripp J, Masters CL, Goudey B (2023) for the Alzheimer’s disease neuroimaging initiative. Disease progression modelling of Alzheimer’s disease using probabilistic principal components analysis. Neuroimage 278:120279

Article  CAS  PubMed  Google Scholar 

Lane CA, Hardy J, Schott JM (2018) Alzheimer’s disease. Eur J Neurol 25:59–70

Article  CAS  PubMed  Google Scholar 

Marucci G, Michela B, Ben D, Lambertucci C, Volpini R, Amenta F (2021) Efficacy of acetylcholinesterase inhibitors in Alzheimer’s disease. Neuropharmacology 190:108352

Article  CAS  PubMed  Google Scholar 

Erdemir F, Barut Celepci D, Aktaş A, Gök Y, Kaya R, Taslimi P, Demir Y, Gülçin İ (2019) Novel 2-aminopyridine liganded Pd(II) N-heterocyclic carbene complexes: synthesis, characterization, crystal structure and bioactivity properties. Bioorg Chem 91:103134

Article  CAS  PubMed  Google Scholar 

Mutlu M, Bingöl Z, Uç EM, Koksal E, Gören AC, Alwasel SH, Gülçin İ (2023) Comprehensive metabolite profiling of cinnamon (Cinnamomum zeylanicum) leaf oil using LC-HR/MS, GC/MS, and GC-FID: Determination of antiglaucoma, antioxidant, anticholinergic, and antidiabetic profiles. Life 13(1):136

Article  CAS  PubMed  PubMed Central  Google Scholar 

Lee DA, Higginbotham EJ (2005) Glaucoma and its treatment: a review. Am J Health Syst Pharm 62:691–699

Article  PubMed  Google Scholar 

Aktas A, Barut Celepci D, Gök Y, Taslimi P, Akıncıoğlu H, Gülçin İ (2020) A novel Ag-N-heterocyclic carbene complex bearing the hydroxyethyl ligand: synthesis, characterization, crystal and spectral structures and bioactivity properties. Crystals 10:171

Article  CAS  Google Scholar 

Gulcin I, Trofimov B, Kaya R, Taslimi P, Sobenina L, Schmidt E, Petrova O, Malysheva S, Gusarova N, Farzaliyev V, Sujayev A, Alwasel S, Supuran CT (2020) Synthesis of nitrogen, phosphorus, selenium and sulfur-containing heterocyclic compounds-determination of their carbonic anhydrase, acetylcholinesterase, butyrylcholinesterase and α-glucosidase inhibition properties. Bioorg Chem 103:104171

Article  CAS  PubMed  Google Scholar 

Lolak N, Akocak S, Turkes C, Taslimi P, Işık M, Beydemir Ş, Gulçin İ, Durgun M (2020) Synthesis, characterization, inhibition effects, and molecular docking studies as acetylcholinesterase, α-glycosidase, and carbonic anhydrase inhibitors of novel benzenesulfonamides incorporating 1,3,5-triazine structural motifs. Bioorg Chem 100:103897

Article  CAS  PubMed  Google Scholar 

Clarke R, Merlin M (2016) Cannabis: evolution, ethnobotany. Univ of California Press, California

Google Scholar 

Rezapour-Firouzi S (2017) Herbal oil supplement with hot-nature diet formultiple sclerosis. In: Watson RR, Killgore WDS (Eds), Nutrition and lifestyle in neurological autoimmune diseases. Chapter 24, p. 229–245

Raoui K, Kabdy H, Ettitaou A, Aitbaba A, Baslam A, Benrazzouk K, Laaradia M.A, Laaradraoui J, Oufquir S, Elyazouli L, Aboufatima R, Garzoli S, Chait A ( 2024) Assessment of Moroccan Cannabis sativa seed oil: chemical analysis and evaluation of antioxidant, toxicological, and antinociceptive effects. Chem Biodiv e202400591

Kiziltaş H, Bingöl Z, Gören AC, Alwasel SH, Gülçin İ (2023) Verbascum speciousum Schrad: analysis of phenolic compounds by LC-HRMS and determination of antioxidant and enzyme inhibitory properties. Rec Nat Prod 17(3):485–500

Google Scholar 

Karagecili H, Yılmaz MA, Ertürk A, Kızıltaş H, Güven L, Alwasel SH, Gulçin İ (2023) Comprehensive metabolite profiling of Berdav propolis using LC-MS/MS: determination of antioxidant, anticholinergic, antiglaucoma, and antidiabetic effects. Molecules 28(4):1739

Article  CAS  PubMed  PubMed Central  Google Scholar 

Magnusson B (2014) The fitness for purpose of analytical methods: a laboratory guide to method validation and related topics 2014

Patino-Bayona WR, Plazas E, Bustos-Cortes JJ, Prieto-Rodriguez JA, Patino-Ladino OJ (2021) Essential oils of three Hypericum species from Colombia: chemical composition, insecticidal and repellent activity against Sitophilus zeamais Motsch. (Coleoptera: Curculionidae). Rec Nat Prod 15:111–121

Article  CAS  Google Scholar 

Salinas M, Bec N, Calva J, Ramírez J, Andrade JM, Larroque C, Vidari G, Armijo C (2020) Chemical composition and anticholinesterase activity of the essential oil from the Ecuadorian plant Salvia pichinchensis Benth. Rec Nat Prod 14(4):276–285

Article  CAS  Google Scholar 

Gulcin I, Mshvildadze V, Gepdiremen A, Elias R (2006) Antioxidant activity of a triterpenoid glycoside isolated from the berries of Hedera colchica: 3-O-(β-D-glucopyranosyl)-hederagenin. Phytother Res 20(2):130–134

Article  CAS  PubMed  Google Scholar 

Apak R, Calokerinos A, Gorinstein S, Segundo MA, Hibbert DB, Gulcin İ, Demirci Cekic S, Güclü K, Ozyürek M, Esin Celik S, Magalhaes LM, Arancibia-Avila P (2022) Methods to evaluate the scavenging activity of antioxidants toward reactive oxygen and nitrogen species. Pure Appl Chem 94(1):87–144

Article  CAS  Google Scholar 

Kabre P, Ouattara L, Sanou Y, Ouedraogo RJ, Ouoba P, Zante A, Zoungo D, Somda MB, Ouedraogo GA (2023) Comparative study of polyphenols, flavonoids content, antioxidant and antidiabetic activities of Lophira lanceolata Tiegh. ex keay (Ochnaceae) extracts. Sci Afr 22:e01922

CAS  Google Scholar 

Gulcin İ, Gören AC, Taslimi P, Alwasel SH, Kilic O, Bursal E (2020) Anticholinergic, antidiabetic and antioxidant activities of Anatolian pennyroyal (Mentha pulegium)-analysis of its polyphenol contents by LC-MS/MS. Biocatal Agric Biotechnol 23:101441

Article  Google Scholar 

Tohma H, Köksal E, Kılıç Ö, Alan Y, Yılmaz MA, Gülçin İ, Bursal E, Alwasel SH (2016) RP-HPLC/MS/MS analysis of the phenolic compounds, antioxidant and antimicrobial activities of Salvia L. species. Antioxidants 5:38

Article  PubMed  PubMed Central  Google Scholar 

Blois MS (1958) Antioxidant determinations by the use of a stable free radical. Nature 181:1199–1200

Article  CAS  Google Scholar 

Ozden EM, Bingol Z, Mutlu M, Karagecili H, Köksal E, Goren AC, Alwasel SH, Gulcin İ (2023) Antioxidant, antiglaucoma, anticholinergic, and antidiabetic effects of kiwifruit (Actinidia deliciosa) oil: metabolite profile analysis using LC-HR/MS, GC/MS and GC-FID. Life 13(9):1939. https://doi.org/10.3390/life13091939

Article  CAS  PubMed  PubMed Central  Google Scholar 

Karageçili H, Yılmaz MA, Alwasel SH, Arık M, Gulçin İ (2023) Antioxidant, antidiabetic, antiglaucoma, and anticholinergic effects of Tayfi grape (Vitis vinifera): a phytochemical screening by LC-MS/MS analysis. Open Chem 21(1):20230120

Article  Google Scholar 

Gulcin İ, Alwasel SH (2022) Metal ions, metal chelators and metal chelating assay as antioxidant method. Processes 10(1):132

Article 

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