Klompas M, Branson R, Cawcutt K, Crist M, Eichenwald EC, Greene LR, Lee G, Maragakis LL, Powell K, Priebe GP, Speck K, Yokoe DS, Berenholtz SM. Strategies to prevent ventilator-associated pneumonia, ventilator-associated events, and nonventilator hospital-acquired pneumonia in acute-care hospitals: 2022 Update. Infect Control Hosp Epidemiol. 2022;43(6):687–713. https://doi.org/10.1017/ice.2022.88.

Article  PubMed  PubMed Central  Google Scholar 

Wu D, Wu C, Zhang S, Zhong Y. Risk factors of ventilator-associated pneumonia in critically III patients. Front Pharmacol. 2019;9(10):482. https://doi.org/10.3389/fphar.2019.00482.

Article  CAS  Google Scholar 

Mehta A, Bhagat R. Preventing ventilator-associated infections. Clin Chest Med. 2016;37(4):683–92. https://doi.org/10.1016/j.ccm.2016.07.008.

Article  PubMed  Google Scholar 

Mietto C, Pinciroli R, Patel N, Berra L. Ventilator associated pneumonia: evolving definitions and preventive strategies. Respir Care. 2013;58(6):990–1007. https://doi.org/10.4187/respcare.02380.

Article  PubMed  Google Scholar 

Cairns S, Thomas JG, Hooper SJ, Wise MP, Frost PJ, Wilson MJ, Lewis MA, Williams DW. Molecular analysis of microbial communities in endotracheal tube biofilms. PLoS ONE. 2011;6(3):e14759. https://doi.org/10.1371/journal.pone.0014759.

Article  CAS  PubMed  PubMed Central  Google Scholar 

Barnes M, Feit C, Grant TA, Brisbois EJ. Antimicrobial polymer modifications to reduce microbial bioburden on endotracheal tubes and ventilator associated pneumonia. Acta Biomater. 2019;91:220–34. https://doi.org/10.1016/j.actbio.2019.04.042.

Article  CAS  PubMed  Google Scholar 

Coppadoro A, Berra L, Bigatello LM. Modifying endotracheal tubes to prevent ventilator-associated pneumonia. Curr Opin Infect Dis. 2011;24(2):157–62. https://doi.org/10.1097/QCO.0b013e328343b733.

Article  PubMed  Google Scholar 

Diaconu O, Siriopol I, Poloșanu LI, Grigoraș I. Endotracheal tube biofilm and its impact on the pathogenesis of ventilator-associated pneumonia. J Crit Care Med (Targu Mures). 2018;4(2):50–5. https://doi.org/10.2478/jccm-2018-0011.

Article  PubMed  Google Scholar 

Vandecandelaere I, Coenye T. Microbial composition and antibiotic resistance of biofilms recovered from endotracheal tubes of mechanically ventilated patients. Adv Exp Med Biol. 2015;830:137–55. https://doi.org/10.1007/978-3-319-11038-7_9.

Article  PubMed  Google Scholar 

Vandecandelaere I, Matthijs N, Van Nieuwerburgh F, Deforce D, Vosters P, De Bus L, Nelis HJ, Depuydt P, Coenye T. Assessment of microbial diversity in biofilms recovered from endotracheal tubes using culture dependent and independent approaches. PLoS ONE. 2012;7(6):e38401. https://doi.org/10.1371/journal.pone.0038401.

Article  CAS  PubMed  PubMed Central  Google Scholar 

Sarda C, Fazal F, Rello J. Management of ventilator-associated pneumonia (VAP) caused by resistant gram-negative bacteria: which is the best strategy to treat? Expert Rev Respir Med. 2019;13(8):787–98. https://doi.org/10.1080/17476348.2019.1632195.

Article  CAS  PubMed  Google Scholar 

Mahmoodpoor A, Sanaie S, Parthvi R, Shadvar K, Hamishekar H, Iranpour A, Nuri H, Rahnemayan S, Nader ND. A clinical trial of silver-coated and tapered cuff plus supraglottic suctioning endotracheal tubes in preventing ventilator-associated pneumonia. J Crit Care. 2020;56:171–6. https://doi.org/10.1016/j.jcrc.2019.12.024.

Article  CAS  PubMed  Google Scholar 

Kollef MH, Afessa B, Anzueto A, Veremakis C, Kerr KM, Margolis BD, Craven DE, Roberts PR, Arroliga AC, Hubmayr RD, Restrepo MI, Auger WR, Schinner R, NASCENT Investigation Group. Silver-coated endotracheal tubes and incidence of ventilator-associated pneumonia: the NASCENT randomized trial. JAMA. 2008;300(7):805–13. https://doi.org/10.1001/jama.300.7.805.

Article  CAS  PubMed  Google Scholar 

Liedberg H, Lundeberg T. Silver alloy coated catheters reduce cathete-r associated bacteriuria. Br J Urol. 1990;65(4):379–81. https://doi.org/10.1111/j.1464-410x.1990.tb14760.x.

Article  CAS  PubMed  Google Scholar 

Morones JR, Elechiguerra JL, Camacho A, Holt K, Kouri JB, Ramírez JT, Yacaman MJ. The bactericidal effect of silver nanoparticles. Nanotechnology. 2005;16:2346.

Article  CAS  PubMed  Google Scholar 

Hemeg HA. Nanomaterials for alternative antibacterial therapy. Int J Nanomed. 2017;12:8211.

Article  CAS  Google Scholar 

Hartmann M, Guttmann J, Müller B, Hallmann T, Geiger K. Reduction of the bacterial load by the silver-coated endotracheal tube (SCET), a laboratory investigation. Technol Health Care. 1999;7(5):359–70.

Article  CAS  PubMed  Google Scholar 

Paladini F, Pollini M, Sannino A, Ambrosio L. Metal-based antibacterial substrates for biomedical applications. Biomacromol. 2015;16(7):1873–85. https://doi.org/10.1021/acs.biomac.5b00773.

Article  CAS  Google Scholar 

Thorarinsdottir HR, Kander T, Holmberg A, Petronis S, Klarin B. Biofilm formation on three different endotracheal tubes: a prospective clinical trial. Crit Care. 2020;24(1):382. https://doi.org/10.1186/s13054-020-03092-1.

Article  PubMed  PubMed Central  Google Scholar 

Balazs DJ, Triandafillu K, Wood P, Chevolot Y, van Delden C, Harms H, Hollenstein C, Mathieu HJ. Inhibition of bacterial adhesion on PVC endotracheal tubes by RF-oxygen glow discharge, sodium hydroxide and silver nitrate treatments. Biomaterials. 2004;25(11):2139–51. https://doi.org/10.1016/j.biomaterials.2003.08.053.

Article  CAS  PubMed  Google Scholar 

Higgins JP, Altman DG, Gøtzsche PC, Jüni P, Moher D, Oxman AD, Savovic J, Schulz KF, Weeks L, Sterne JA, Cochrane Bias Methods Group; Cochrane Statistical Methods Group. The Cochrane Collaboration’s tool for assessing risk of bias in randomised trials. BMJ. 2011;343:d5928. https://doi.org/10.1136/bmj.d5928.

Article  PubMed  PubMed Central  Google Scholar 

Luo D, Wan X, Liu J, Tong T. Optimally estimating the sample mean from the sample size, median, mid-range, and/or mid-quartile range. Stat Methods Med Res. 2018;27(6):1785–805. https://doi.org/10.1177/0962280216669183.

Article  PubMed  Google Scholar 

Damas P, Legrain C, Lambermont B, Dardenne N, Guntz J, Kisoka G, Demaret P, Rousseau AF, Jadot L, Piret S, Noirot D, Bertrand A, Donneau AF, Misset B. Prevention of ventilator-associated pneumonia by noble metal coating of endotracheal tubes: a multi-center, randomized, double-blind study. Ann Intensiv Care. 2022;12(1):1. https://doi.org/10.1186/s13613-021-00961-y.

Article  CAS  Google Scholar 

Mahmodiyeh B, Kamali A, Zarinfar N, Joushani MM. The effect of silver-coated endotracheal tube on the incidence of ventilator-induced pneumonia in intubated patients admitted to the intensive care unit (ICU). Syst Rev Pharm. 2021;12(3):254–8. https://doi.org/10.31838/srp.2021.3.41.

Article  Google Scholar 

Rello J, Kollef M, Diaz E, Sandiumenge A, del Castillo Y, Corbella X, Zachskorn R. Reduced burden of bacterial airway colonization with a novel silver-coated endotracheal tube in a randomized multiple-center feasibility study. Crit Care Med. 2006;34(11):2766–72. https://doi.org/10.1097/01.CCM.0000242154.49632.B0.

Article  PubMed  Google Scholar 

Pirrone M, Imber DA, Marrazzo F, Pinciroli R, Zhang C, Bry L, Delaney ML, Dubois AM, Thomas JG, Nistico L, Melton-Kreft R, Bittner EA, Kacmarek RM, Berra L. Silver-coated endotracheal tubes cleaned with a mechanism for secretion removal. Respir Care. 2019;64(1):1–9. https://doi.org/10.4187/respcare.06222.

Article  PubMed  PubMed Central  Google Scholar 

Olson ME, Harmon BG, Kollef MH. Silver-coated endotracheal tubes associated with reduced bacterial burden in the lungs of mechanically ventilated dogs. Chest. 2002;121(3):863–70. https://doi.org/10.1378/chest.121.3.863.

Article  PubMed  Google Scholar 

Björling G, Johansson D, Bergström L, Jalal S, Kohn I, Frostell C, Kalman S. Tolerability and performance of BIP endotracheal tubes with noble metal alloy coating—a randomized clinical evaluation study. BMC Anesthesiol. 2015;15:174. https://doi.org/10.1186/s12871-015-0156-z.

Article  CAS  PubMed  PubMed Central