The protective role of RACK1 in hepatic ischemia‒reperfusion injury-induced ferroptosis

Ni D, Wei H, Chen W, Bao Q, Rosenkrans ZT, Barnhart TE, et al. Ceria nanoparticles Meet hepatic ischemia-reperfusion Injury: the Perfect Imperfection. Adv Mater. 2019;31(40):e1902956.

Article  PubMed  PubMed Central  Google Scholar 

Du YD, Guo WY, Han CH, Wang Y, Chen XS, Li DW, et al. N6-methyladenosine demethylase FTO impairs hepatic ischemia-reperfusion injury via inhibiting Drp1-mediated mitochondrial fragmentation. Cell Death Dis. 2021;12(5):442.

Article  PubMed  PubMed Central  CAS  Google Scholar 

Huang J, Xie P, Dong Y, An W. Inhibition of Drp1 SUMOylation by ALR protects the liver from ischemia-reperfusion injury. Cell Death Differ. 2021;28(4):1174–92.

Article  PubMed  CAS  Google Scholar 

Bavarsad K, Riahi MM, Saadat S, Barreto G, Atkin SL, Sahebkar A. Protective effects of curcumin against ischemia-reperfusion injury in the liver. Pharmacol Res. 2019;141:53–62.

Article  PubMed  CAS  Google Scholar 

Selzner N, Rudiger H, Graf R, Clavien PA. Protective strategies against ischemic injury of the liver. Gastroenterology. 2003;125(3):917–36.

Article  PubMed  CAS  Google Scholar 

Yamada N, Karasawa T, Wakiya T, Sadatomo A, Ito H, Kamata R, et al. Iron overload as a risk factor for hepatic ischemia-reperfusion injury in liver transplantation: potential role of ferroptosis. Am J Transpl. 2020;20(6):1606–18.

Article  CAS  Google Scholar 

Li Y, Feng D, Wang Z, Zhao Y, Sun R, Tian D, et al. Ischemia-induced ACSL4 activation contributes to ferroptosis-mediated tissue injury in intestinal ischemia/reperfusion. Cell Death Differ. 2019;26(11):2284–99.

Article  PubMed  PubMed Central  CAS  Google Scholar 

Duan F, Wu H, Jia D, Wu W, Ren S, Wang L, et al. O-GlcNAcylation of RACK1 promotes hepatocellular carcinogenesis. J Hepatol. 2018;68(6):1191–202.

Article  PubMed  CAS  Google Scholar 

Adams DR, Ron D, Kiely PA. RACK1, a multifaceted scaffolding protein: structure and function. Cell Commun Signal. 2011;9:22.

Article  PubMed  PubMed Central  CAS  Google Scholar 

Li X, Li J, Qian J, Zhang D, Shen H, Li X et al. Loss of ribosomal RACK1 (receptor for activated protein kinase C 1) Induced by Phosphorylation at T50 alleviates cerebral ischemia-reperfusion Injury in rats. Stroke. 2018:STROKEAHA118022404.

Yan B, Liu S, Li X, Zhong Y, Tong F, Yang S. Preconditioning with endoplasmic reticulum stress alleviated heart ischemia/reperfusion injury via modulating IRE1/ATF6/RACK1/PERK and PGC-1alpha in diabetes mellitus. Biomed Pharmacother. 2019;118:109407.

Article  PubMed  CAS  Google Scholar 

Wang L, Zhang Z, Li M, Wang F, Jia Y, Zhang F, et al. P53-dependent induction of ferroptosis is required for artemether to alleviate carbon tetrachloride-induced liver fibrosis and hepatic stellate cell activation. IUBMB Life. 2019;71(1):45–56.

Article  PubMed  CAS  Google Scholar 

Sui M, Jiang X, Chen J, Yang H, Zhu Y. Magnesium isoglycyrrhizinate ameliorates liver fibrosis and hepatic stellate cell activation by regulating ferroptosis signaling pathway. Biomed Pharmacother. 2018;106:125–33.

Article  PubMed  CAS  Google Scholar 

Jiang H, Fang Y, Wang Y, Li T, Lin H, Lin J, et al. FGF4 improves hepatocytes ferroptosis in autoimmune hepatitis mice via activation of CISD3. Int Immunopharmacol. 2023;116:109762.

Article  PubMed  CAS  Google Scholar 

Suzuki S, Toledo-Pereyra LH, Rodriguez FJ, Cejalvo D. Neutrophil infiltration as an important factor in liver ischemia and reperfusion injury. Modulating effects of FK506 and cyclosporine. Transplantation. 1993;55(6):1265–72.

Article  PubMed  CAS  Google Scholar 

Herzig S, Shaw RJ. AMPK: guardian of metabolism and mitochondrial homeostasis. Nat Rev Mol Cell Biol. 2018;19(2):121–35.

Article  PubMed  CAS  Google Scholar 

Liu H, Wu X, Luo J, Zhao L, Li X, Guo H, et al. Adiponectin peptide alleviates oxidative stress and NLRP3 inflammasome activation after cerebral ischemia-reperfusion injury by regulating AMPK/GSK-3beta. Exp Neurol. 2020;329:113302.

Article  PubMed  CAS  Google Scholar 

Mohsin AA, Chen Q, Quan N, Rousselle T, Maceyka MW, Samidurai A, et al. Mitochondrial complex I inhibition by metformin limits Reperfusion Injury. J Pharmacol Exp Ther. 2019;369(2):282–90.

Article  PubMed  PubMed Central  CAS  Google Scholar 

Li M, Jiao L, Shao Y, Li H, Sun L, Yu Q, et al. LncRNA-ZFAS1 promotes myocardial ischemia-reperfusion Injury through DNA methylation-mediated Notch1 down-regulation in mice. JACC Basic Transl Sci. 2022;7(9):880–95.

Article  PubMed  PubMed Central  CAS  Google Scholar 

Xu J, Huang X, Liu S, Chen D, Xie Y, Zhao Z. The protective effects of lncRNA ZFAS1/miR-421-3p/MEF2C axis on cerebral ischemia-reperfusion injury. Cell Cycle. 2022;21(18):1915–31.

Article  PubMed  PubMed Central  CAS  Google Scholar 

Ni T, Huang X, Pan S, Lu Z. Inhibition of the long non-coding RNA ZFAS1 attenuates ferroptosis by sponging mir-150-5p and activates CCND2 against diabetic cardiomyopathy. J Cell Mol Med. 2021;25(21):9995–10007.

Article  PubMed  PubMed Central  CAS  Google Scholar 

Armaos A, Colantoni A, Proietti G, Rupert J, Tartaglia GG. catRAPID omics v2.0: going deeper and wider in the prediction of protein-RNA interactions. Nucleic Acids Res. 2021;49(W1):W72–9.

Article  PubMed  PubMed Central  CAS  Google Scholar 

Muppirala UK, Honavar VG, Dobbs D. Predicting RNA-protein interactions using only sequence information. BMC Bioinformatics. 2011;12:489.

Article  PubMed  PubMed Central  CAS  Google Scholar 

Yu Z, Jiang X, Qin L, Deng H, Wang J, Ren W, et al. A novel UBE2T inhibitor suppresses Wnt/beta-catenin signaling hyperactivation and gastric cancer progression by blocking RACK1 ubiquitination. Oncogene. 2021;40(5):1027–42.

Article  PubMed  CAS  Google Scholar 

Liu Y, Lu T, Zhang C, Xu J, Xue Z, Busuttil RW, et al. Activation of YAP attenuates hepatic damage and fibrosis in liver ischemia-reperfusion injury. J Hepatol. 2019;71(4):719–30.

Article  PubMed  PubMed Central  CAS  Google Scholar 

Wu Y, Jiao H, Yue Y, He K, Jin Y, Zhang J et al. Ubiquitin ligase E3 HUWE1/MULE targets transferrin receptor for degradation and suppresses ferroptosis in acute liver injury. Cell Death Differ. 2022.

Dixon SJ, Lemberg KM, Lamprecht MR, Skouta R, Zaitsev EM, Gleason CE, et al. Ferroptosis: an iron-dependent form of nonapoptotic cell death. Cell. 2012;149(5):1060–72.

Article  PubMed  PubMed Central  CAS  Google Scholar 

Friedmann Angeli JP, Schneider M, Proneth B, Tyurina YY, Tyurin VA, Hammond VJ, et al. Inactivation of the ferroptosis regulator Gpx4 triggers acute renal failure in mice. Nat Cell Biol. 2014;16(12):1180–91.

Article  PubMed  CAS  Google Scholar 

Gao M, Monian P, Quadri N, Ramasamy R, Jiang X. Glutaminolysis and transferrin regulate Ferroptosis. Mol Cell. 2015;59(2):298–308.

Article  PubMed  PubMed Central  CAS  Google Scholar 

Wu J, Wang Y, Jiang R, Xue R, Yin X, Wu M, et al. Ferroptosis in liver disease: new insights into disease mechanisms. Cell Death Discov. 2021;7(1):276.

Article  PubMed  PubMed Central  CAS 

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