Qin C, Yang S, Chu Y-H, Zhang H, Pang X-W, Chen L, et al. Signaling pathways involved in ischemic stroke: molecular mechanisms and therapeutic interventions. Sig Transduct Target Ther. 2022;7:1–29.
Shehjar F, Maktabi B, Rahman ZA, Bahader GA, James AW, Naqvi A, et al. Stroke: molecular mechanisms and therapies: Update on recent developments. Neurochem Int. 2023;162: 105458.
Article CAS PubMed Google Scholar
Huang Y, Wang Z, Huang Z-X, Liu Z. Biomarkers and the outcomes of ischemic stroke. Front Mol Neurosci. 2023. https://doi.org/10.3389/fnmol.2023.1171101.
Article PubMed PubMed Central Google Scholar
Xiao A, Zhang Y, Ren Y, Chen R, Li T, You C, et al. GDF11 alleviates secondary brain injury after intracerebral hemorrhage via attenuating mitochondrial dynamic abnormality and dysfunction. Sci Rep. 2021;11:3974.
Article CAS PubMed PubMed Central Google Scholar
Wang P-Q, Wu Y, Zhang M, Huo H-R, Du X-L, Sui F. Analysis of protective effects of Chaihu Jia Longgu Muli Tang against ischemic stroke by combining traditional Chinese medicine pathogenesis and efficacy with modern pathology and pharmacology. Zhongguo Zhong Yao Za Zhi. 2018;43:2448–53.
Song J, Xu C, Zhang J, Gao L. From clinical appearance to accurate management in acute ischemic stroke patients: with the guidance of innovative traditional Chinese medicine diagnosis. Brain and Behavior. 2019;9: e01411.
Article PubMed PubMed Central Google Scholar
Luan X, Zhang L-J, Li X-Q, Rahman K, Zhang H, Chen H-Z, et al. Compound-based Chinese medicine formula: from discovery to compatibility mechanism. J Ethnopharmacol. 2020;254: 112687.
Article CAS PubMed Google Scholar
Li J, Yu J, Ma H, Yang N, Li L, Zheng D, et al. Intranasal pretreatment with Z-Ligustilide, the main volatile component of rhizoma chuanxiong, confers prophylaxis against cerebral ischemia via Nrf2 and HSP70 signaling pathways. J Agric Food Chem. 2017;65:1533–42.
Article CAS PubMed Google Scholar
Shi Y-H, Zhang X-L, Ying P-J, Wu Z-Q, Lin L-L, Chen W, et al. Neuroprotective effect of astragaloside IV on cerebral ischemia/reperfusion injury rats through sirt1/mapt pathway. Front Pharmacol. 2021. https://doi.org/10.3389/fphar.2021.639898/full.
Article PubMed PubMed Central Google Scholar
Guo W, Xu X, Xiao Y, Zhang J, Shen P, Lu X, et al. Salvianolic acid C attenuates cerebral ischemic injury through inhibiting neuroinflammation via the TLR4-TREM1-NF-κB pathway. Chin Med. 2024;19:46.
Article CAS PubMed PubMed Central Google Scholar
Zhao F, Peng C, Li H, Chen H, Yang Y, Ai Q, et al. Paeoniae Radix Rubra extract attenuates cerebral ischemia injury by inhibiting ferroptosis and activating autophagy through the PI3K/Akt signalling pathway. J Ethnopharmacol. 2023;315: 116567.
Article CAS PubMed Google Scholar
He L, Chen X, Zhou M, Zhang D, Yang J, Yang M, et al. Radix/rhizoma notoginseng extract (Sanchitongtshu) for ischemic stroke: a randomized controlled study. Phytomedicine. 2011;18:437–42.
Sun Z-Y, Wang F-J, Guo H, Chen L, Chai L-J, Li R-L, et al. Shuxuetong injection protects cerebral microvascular endothelial cells against oxygen-glucose deprivation reperfusion. Neural Regen Res. 2019;14:783.
Article CAS PubMed PubMed Central Google Scholar
Zheng M, Zhou M. Neuroprotective effect of daidzein extracted from pueraria lobate radix in a stroke model via the Akt/mTOR/BDNF channel. Front Pharmacol. 2022. https://doi.org/10.3389/fphar.2021.772485/full.
Article PubMed PubMed Central Google Scholar
Zhou Y-X, Zhang H, Peng C. Puerarin: a review of pharmacological effects. Phytother Res. 2014;28:961–75.
Article CAS PubMed Google Scholar
Peng K, Zhu Z, Cai Z, Ma K, Luo L, Liu M, et al. Traditional Chinese medicine composition, preparation method thereof and application of traditional Chinese medicine composition in preparation of medicine for treating or preventing chronic cerebral blood supply insufficiency. 2023.
Ma Z, Jia C, Guo J, Gu H, Miao Y. Features analysis of five-element theory and its basal effects on construction of visceral manifestation theory. J Tradit Chin Med. 2014;34:115–21.
Article CAS PubMed Google Scholar
Zhao Y, Zhuang Y. Modern interpretation of “exterior-interior correlation between lung and large intestine” theory in acute and critical cases. Zhonghua Wei Zhong Bing Ji Jiu Yi Xue. 2020;32:1040–4.
Han Z-T. Brain governing mind theory in traditional chinese medicine. Zhonghua Yi Shi Za Zhi. 2012;42:195–8.
Ge Y, Wang X, Guo Y, Yan J, Abuduwaili A, Aximujiang K, et al. Gut microbiota influence tumor development and Alter interactions with the human immune system. J Exp Clin Cancer Res. 2021;40:42.
Article PubMed PubMed Central Google Scholar
Camara-Lemarroy CR, Ibarra-Yruegas BE, Gongora-Rivera F. Gastrointestinal complications after ischemic stroke. J Neurol Sci. 2014;346:20–5.
Chidambaram SB, Rathipriya AG, Mahalakshmi AM, Sharma S, Hediyal TA, Ray B, et al. The influence of gut dysbiosis in the pathogenesis and management of ischemic stroke. Cells. 2022;11:1239.
Article CAS PubMed PubMed Central Google Scholar
Xu K, Gao X, Xia G, Chen M, Zeng N, Wang S, et al. Rapid gut dysbiosis induced by stroke exacerbates brain infarction in turn. Gut. 2021;70:1486–94.
Rahman Z, Bhale NA, Dikundwar AG. Multistrain probiotics with fructooligosaccharides improve middle cerebral artery occlusion-driven neurological deficits by revamping microbiota-gut-brain axis. Probiot Antimicro Prot. 2023. https://doi.org/10.1007/s12602-023-10109-y.
Wang Q, Yang Q, Liu X. The microbiota–gut–brain axis and neurodevelopmental disorders. Protein Cell. 2023;14:762–75.
Article CAS PubMed PubMed Central Google Scholar
Liu L, Huh JR, Shah K. Microbiota and the gut-brain-axis: Implications for new therapeutic design in the CNS. eBioMedicine. 2022;77:103908.
Article CAS PubMed PubMed Central Google Scholar
Brown EM, Clardy J, Xavier RJ. Gut microbiome lipid metabolism and its impact on host physiology. Cell Host Microbe. 2023;31:173–86.
Article CAS PubMed PubMed Central Google Scholar
Brouns R, Verkerk R, Aerts T, De Surgeloose D, Wauters A, Scharpé S, et al. The role of tryptophan catabolism along the kynurenine pathway in acute ischemic stroke. Neurochem Res. 2010;35:1315–22.
Article CAS PubMed Google Scholar
Lian Z, Xu Y, Wang C, Chen Y, Yuan L, Liu Z, et al. Gut microbiota-derived melatonin from Puerariae Lobatae radix-resistant starch supplementation attenuates ischemic stroke injury via a positive microbial co-occurrence pattern. Pharmacol Res. 2023;190: 106714.
Article CAS PubMed Google Scholar
Zhou Y, Chen Y, He H, Peng M, Zeng M, Sun H. The role of the indoles in microbiota-gut-brain axis and potential therapeutic targets: a focus on human neurological and neuropsychiatric diseases. Neuropharmacology. 2023;239: 109690.
Article CAS PubMed Google Scholar
Zhang Q, Zhao Q, Li T, Lu L, Wang F, Zhang H, et al. Lactobacillus plantarum-derived indole-3-lactic acid ameliorates colorectal tumorigenesis via epigenetic regulation of CD8+ T cell immunity. Cell Metab. 2023;35:943-960.e9.
Article CAS PubMed Google Scholar
Wong CB, Tanaka A, Kuhara T, Xiao J. Potential effects of indole-3-lactic acid, a metabolite of human bifidobacteria, on ngf-induced neurite outgrowth in PC12 cells. Microorganisms. 2020;8:398.
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