DGA ameliorates severe acute pancreatitis through modulating macrophage pyroptosis

Roberts S, et al. The incidence and aetiology of acute pancreatitis across Europe. Pancreatology: Official J Int Association Pancreatology (IAP). 2017;17(2):155–65. … et al.].

Article  Google Scholar 

Dumnicka P et al. The interplay between inflammation, Coagulation and Endothelial Injury in the early phase of Acute Pancreatitis: clinical implications. Int J Mol Sci, 2017. 18(2).

Richardson A, Park W. Acute pancreatitis and diabetes mellitus: a review. Korean J Intern Med. 2021;36(1):15–24.

Article  CAS  PubMed  Google Scholar 

Vogel M et al. High risk of complications and acute-on-chronic liver failure in cirrhosis patients with acute pancreatitis. Eur J Intern Med, 2022.

Iyer H, et al. Pulmonary complications of acute pancreatitis. Expert Rev Respir Med. 2020;14(2):209–17.

Article  CAS  PubMed  Google Scholar 

Ma D, et al. Inhibition of ferroptosis attenuates acute kidney Injury in rats with severe Acute Pancreatitis. Dig Dis Sci. 2021;66(2):483–92.

Article  CAS  PubMed  Google Scholar 

Lankisch P, Apte M, Banks P. Acute pancreatitis. Lancet (London England). 2015;386(9988):85–96.

Article  PubMed  Google Scholar 

Liu K, et al. Trypsin-mediated sensitization to Ferroptosis increases the severity of pancreatitis in mice. Cell Mol Gastroenterol Hepatol. 2022;13(2):483–500.

Article  PubMed  Google Scholar 

Peng C, Li Z, Yu X. The role of pancreatic infiltrating Innate Immune cells in Acute Pancreatitis. Int J Med Sci. 2021;18(2):534–45.

Article  CAS  PubMed  PubMed Central  Google Scholar 

Sah RP, Garg P, Saluja AK. Pathogenic mechanisms of acute pancreatitis. Curr Opin Gastroenterol. 2012;28(5):507–15.

Article  CAS  PubMed  PubMed Central  Google Scholar 

Shrivastava P, Bhatia M. Essential role of monocytes and macrophages in the progression of acute pancreatitis. World J Gastroenterol. 2010;16(32):3995–4002.

Article  CAS  PubMed  PubMed Central  Google Scholar 

Luan ZG, et al. Downregulation of HMGB1 protects against the development of acute lung injury after severe acute pancreatitis. Immunobiology. 2013;218(10):1261–70.

Article  CAS  PubMed  Google Scholar 

Castanheira FVS, Kubes P. Neutrophils and NETs in modulating acute and chronic inflammation. Blood. 2019;133(20):2178–85.

Article  CAS  PubMed  Google Scholar 

Xue J, et al. Alternatively activated macrophages promote pancreatic fibrosis in chronic pancreatitis. Nat Commun. 2015;6:7158.

Article  CAS  PubMed  Google Scholar 

Bhatia M, et al. Treatment with bindarit, a blocker of MCP-1 synthesis, protects mice against acute pancreatitis. Am J Physiol Gastrointest Liver Physiol. 2005;288(6):G1259–65.

Article  CAS  PubMed  Google Scholar 

Makhija R, Kingsnorth A. Cytokine storm in acute pancreatitis. J Hepato-biliary-Pancreat Surg. 2002;9(4):401–10.

Article  Google Scholar 

Zhou Q, et al. Emodin alleviates intestinal barrier dysfunction by inhibiting apoptosis and regulating the Immune response in severe Acute Pancreatitis. Pancreas. 2021;50(8):1202–11.

Article  CAS  PubMed  PubMed Central  Google Scholar 

Zhen J, et al. Baicalin protects against Acute Pancreatitis Involving JNK Signaling Pathway via regulating miR-15a. Am J Chin Med. 2021;49(1):147–61.

Article  CAS  PubMed  Google Scholar 

Wang J, et al. Cathepsin B aggravates acute pancreatitis by activating the NLRP3 inflammasome and promoting the caspase-1-induced pyroptosis. Int Immunopharmacol. 2021;94:107496.

Article  CAS  PubMed  Google Scholar 

Wen Y, et al. Chaiqin chengqi decoction alleviates severity of acute pancreatitis via inhibition of TLR4 and NLRP3 inflammasome: identification of bioactive ingredients via pharmacological sub-network analysis and experimental validation. Phytomedicine: Int J Phytotherapy Phytopharmacology. 2020;79:153328.

Article  CAS  Google Scholar 

Rong Y, et al. Resveratrol suppresses severe Acute Pancreatitis-Induced Microcirculation disturbance through Targeting SIRT1-FOXO1 Axis. Oxidative Med Cell Longev. 2021;2021:p8891544.

Article  Google Scholar 

Huang Zhenning LL. Research progress in treatment of acute pancreatitis with traditional Chinese medicine. Volume 37. GUANGXI MEDICAL UNIVERSITY; 2020. 12.

Zhenpan X, Zhuyin. Summary of the national expert seminar on the treatment of acute pancreatitis with traditional Chinese medicine. Chin Pancreatol, 2021. 21.1.

Chen W, et al. Tanshinone IIA protects against Acute Pancreatitis in mice by inhibiting oxidative stress via the Nrf2/ROS pathway. Oxidative Med Cell Longev. 2020;2020:p5390482.

Article  Google Scholar 

Wang M, et al. Protective effects of HY1702 on lipopolysaccharide-induced mild acute respiratory distress syndrome in mice. Eur J Pharmacol. 2020;887:173563.

Article  CAS  PubMed  PubMed Central  Google Scholar 

Kong T, et al. Diterpenoid DGA induces apoptosis via endoplasmic reticulum stress caused by changes in glycosphingolipid composition and inhibition of STAT3 in glioma cells. Biochem Pharmacol. 2022;205:115254.

Article  CAS  PubMed  Google Scholar 

Jiang X, et al. Glaucocalyxin A reverses EMT and TGF-β1-induced EMT by inhibiting TGF-β1/Smad2/3 signaling pathway in osteosarcoma. Chem Biol Interact. 2019;307:158–66.

Article  CAS  PubMed  Google Scholar 

Zhang Q, et al. Activation of Nrf2/HO-1 signaling: an important molecular mechanism of herbal medicine in the treatment of atherosclerosis via the protection of vascular endothelial cells from oxidative stress. J Adv Res. 2021;34:43–63.

Article  CAS  PubMed  PubMed Central  Google Scholar 

Chen S, et al. Protective effects of glaucocalyxin A on the airway of asthmatic mice. Open Med (Wars). 2022;17(1):1158–71.

Article  CAS  PubMed  Google Scholar 

Cao J, et al. Glaucocalyxin A alleviates lipopolysaccharide-induced inflammation and apoptosis in pulmonary microvascular endothelial cells and permeability injury by inhibiting STAT3 signaling. Exp Ther Med. 2022;23(4):313.

Article  CAS  PubMed  PubMed Central  Google Scholar 

Hou X, et al. Glaucocalyxin A alleviates LPS-mediated septic shock and inflammation via inhibiting NLRP3 inflammasome activation. Int Immunopharmacol. 2020;81:106271.

Article  CAS  PubMed  Google Scholar 

Vande Walle L, Lamkanfi M. Drugging the NLRP3 inflammasome: from signalling mechanisms to therapeutic targets. Nat Rev Drug Discovery, 2023.

Yu H, et al. Targeting NF-kappaB pathway for the therapy of diseases: mechanism and clinical study. Signal Transduct Target Ther. 2020;5(1):209.

Article  CAS  PubMed  PubMed Central  Google Scholar 

bingbing W. Effect of Resolvin D1 on the autophgy and NLRP3 inflammasomes of experimental acute pancreatitis in mice. Anhui Medical University; 2018.

Fu J, et al. GABA regulates IL-1beta production in macrophages. Cell Rep. 2022;41(10):111770.

Article  CAS  PubMed  Google Scholar 

He Y, Hara H, Nunez G. Mechanism and regulation of NLRP3 inflammasome activation. Trends Biochem Sci. 2016;41(12):1012–21.

Article  CAS  PubMed  PubMed Central  Google Scholar 

Sendler M, et al. NLRP3 inflammasome regulates development of systemic inflammatory response and compensatory anti-inflammatory response syndromes in mice with Acute Pancreatitis. Gastroenterology. 2020;158(1):253–.

Article  CAS  PubMed 

留言 (0)

沒有登入
gif