Bedford J, Enria D, Giesecke J, Heymann DL, Ihekweazu C, Kobinger G, Lane HC, Memish Z, Oh MD, Sall AA, et al. COVID-19: towards controlling of a pandemic. Lancet. 2020;395:1015–8.
Article CAS PubMed PubMed Central Google Scholar
Naseer S, Khalid S, Parveen S, Abbass K, Song H, Achim MV. COVID-19 outbreak: impact on global economy. Front Public Health. 2022;10:1009393.
Dessie ZG, Zewotir T. Mortality-related risk factors of COVID-19: a systematic review and meta-analysis of 42 studies and 423,117 patients. BMC Infect Dis. 2021;21:855.
Article CAS PubMed PubMed Central Google Scholar
Choi YJ, Park JY, Lee HS, Suh J, Song JY, Byun MK, Cho JH, Kim HJ, Park HJ. Variable effects of underlying diseases on the prognosis of patients with COVID-19. PLoS ONE. 2021;16:e0254258.
Article CAS PubMed PubMed Central Google Scholar
Baldelli L, Marjot T, Barnes E, Barritt AS, Webb GJ, Moon AM. SARS-CoV-2 infection and liver disease: a review of Pathogenesis and outcomes. Gut Liver. 2023;17:12–23.
Article CAS PubMed Google Scholar
Ioannou GN, Liang PS, Locke E, Green P, Berry K, O’Hare AM, Shah JA, Crothers K, Eastment MC, Fan VS, Dominitz JA. Cirrhosis and severe Acute Respiratory Syndrome Coronavirus 2 infection in US veterans: risk of infection, hospitalization, Ventilation, and Mortality. Hepatology. 2021;74:322–35.
Article CAS PubMed Google Scholar
Spearman CW, Aghemo A, Valenti L, Sonderup MW. COVID-19 and the liver: a 2021 update. Liver Int. 2021;41:1988–98.
Article CAS PubMed Google Scholar
Marjot T, Webb GJ, Barritt ASt, Moon AM, Stamataki Z, Wong VW, Barnes E. COVID-19 and liver disease: mechanistic and clinical perspectives. Nat Rev Gastroenterol Hepatol. 2021;18:348–64.
Article CAS PubMed PubMed Central Google Scholar
Ge J, Pletcher MJ, Lai JC. Outcomes of SARS-CoV-2 infection in patients with chronic liver disease and cirrhosis: a National COVID Cohort Collaborative Study. Gastroenterology. 2021;161:1487–e15011485.
Article CAS PubMed Google Scholar
Moon AM, Webb GJ, García-Juárez I, Kulkarni AV, Adali G, Wong DK, Lusina B, Dalekos GN, Masson S, Shore BM, et al. SARS-CoV-2 infections among patients with Liver Disease and Liver Transplantation who received COVID-19 vaccination. Hepatol Commun. 2022;6:889–97.
Article CAS PubMed Google Scholar
Cromer D, Steain M, Reynaldi A, Schlub TE, Khan SR, Sasson SC, Kent SJ, Khoury DS, Davenport MP. Predicting vaccine effectiveness against severe COVID-19 over time and against variants: a meta-analysis. Nat Commun. 2023;14:1633.
Article CAS PubMed PubMed Central Google Scholar
Zampino R, Mele F, Florio LL, Bertolino L, Andini R, Galdo M, De Rosa R, Corcione A, Durante-Mangoni E. Liver injury in remdesivir-treated COVID-19 patients. Hepatol Int. 2020;14:881–3.
Wong GL, Hui VW, Yip TC, Lui GC, Hui DS, Wong VW. Minimal risk of Drug-Induced Liver Injury with Molnupiravir and Ritonavir-Boosted Nirmatrelvir. Gastroenterology. 2023;164:151–3.
Article CAS PubMed Google Scholar
Gaziano L, Giambartolomei C, Pereira AC, Gaulton A, Posner DC, Swanson SA, Ho Y-L, Iyengar SK, Kosik NM, Vujkovic M, et al. Actionable druggable genome-wide mendelian randomization identifies repurposing opportunities for COVID-19. Nat Med. 2021;27:668–76.
Article CAS PubMed PubMed Central Google Scholar
Brevini T, Maes M, Webb GJ, John BV, Fuchs CD, Buescher G, Wang L, Griffiths C, Brown ML, Scott WE, et al. FXR inhibition may protect from SARS-CoV-2 infection by reducing ACE2. Nature. 2023;615:134–42.
Article CAS PubMed Google Scholar
Li Y, Zhu N, Cui X, Lin Y, Li X. Protective effect of ursodeoxycholic acid on COVID-19 in patients with chronic liver disease. Front Cell Infect Microbiol. 2023;13:1178590.
Article CAS PubMed PubMed Central Google Scholar
John BV, Bastaich D, Webb G, Brevini T, Moon A, Ferreira RD, Chin AM, Kaplan DE, Taddei TH, Serper M, et al. Ursodeoxycholic acid is associated with a reduction in SARS-CoV-2 infection and reduced severity of COVID-19 in patients with cirrhosis. J Intern Med. 2023;293:636–47.
Article CAS PubMed Google Scholar
Hu L, Zhang H, Huang C, Shen T, Feng Z, Mu F, Xu L, Lin Y, Yue C, Guo K, et al. Effect of Ursodeoxycholic Acid on preventing SARS-CoV-2 infection in patients with liver transplantation: a multicenter retrospective cohort study. Qjm; 2023.
Colapietro F, Angelotti G, Masetti C, Shiffer D, Pugliese N, De Nicola S, Carella F, Desai A, Ormas M, Calatroni M et al. Ursodeoxycholic Acid Does Not Improve COVID-19 Outcome in Hospitalized Patients. Viruses : 2023, 15.
Liu T, Wang JS. Ursodeoxycholic acid administration did not reduce susceptibility to SARS-CoV-2 infection in children. Liver Int. 2023;43:1950–4.
Article CAS PubMed Google Scholar
Marrone G, Covino M, Merra G, Piccioni A, Amodeo A, Novelli A, Murri R, Pompili M, Gasbarrini A, Franceschi F. Ursodeoxycholic acid does not affect the clinical outcome of SARS-CoV-2 infection: a retrospective study of propensity score-matched cohorts. Liver Int. 2024;44:83–92.
Article CAS PubMed Google Scholar
Corpechot C, Verdoux M, Frank-Soltysiak M, Duclos-Vallée JC, Grimaldi L. Exploring the impact of ursodeoxycholic acid therapy on COVID-19 in a real-word setting. J Med Virol. 2024;96:e29418.
Article CAS PubMed Google Scholar
Nation Health Insurance Data Sharing Service. 2024. [https://nhiss.nhis.or.kr/bd/ab/bdaba000eng.do]
ATC/DDD, Index. 2024. [https://atcddd.fhi.no/atc_ddd_index/code=A05AA02]
Quan H, Li B, Couris CM, Fushimi K, Graham P, Hider P, Januel JM, Sundararajan V. Updating and validating the Charlson comorbidity index and score for risk adjustment in hospital discharge abstracts using data from 6 countries. Am J Epidemiol. 2011;173:676–82.
Lee SR, Lee HJ, Choi EK, Han KD, Jung JH, Cha MJ, Oh S, Lip GYH. Direct oral anticoagulants in patients with Atrial Fibrillation and Liver Disease. J Am Coll Cardiol. 2019;73:3295–308.
Article CAS PubMed Google Scholar
Fan VS, Dominitz JA, Eastment MC, Locke ER, Green P, Berry K, O’Hare AM, Shah JA, Crothers K, Ioannou GN. Risk factors for testing positive for severe Acute Respiratory Syndrome Coronavirus 2 in a National United States Healthcare System. Clin Infect Dis. 2021;73:e3085–94.
Article CAS PubMed Google Scholar
Lindor KD, Bowlus CL, Boyer J, Levy C, Mayo M. Primary biliary cholangitis: 2018 Practice Guidance from the American Association for the study of Liver diseases. Hepatology. 2019;69:394–419.
Lee HA, Chang Y, Sung PS, Yoon EL, Lee HW, Yoo J-J, Lee Y-S, An J, Song DS, Cho YY, et al. Therapeutic mechanisms and beneficial effects of non-antidiabetic drugs in chronic liver diseases. Clin Mol Hepatol. 2022;28:425–72.
Article PubMed PubMed Central Google Scholar
Chang J-I, Kim JH, Sinn DH, Cho J-Y, Kim KM, Oh JH, Park Y, Sohn W, Goh MJ, Kang W, et al. Clinical outcomes and validation of Ursodeoxycholic Acid Response scores in patients with Korean primary biliary cholangitis: a Multicenter Cohort Study. Gut Liver. 2023;17:620–8.
Article CAS PubMed PubMed Central Google Scholar
Poupon R. Ursodeoxycholic acid and bile-acid mimetics as therapeutic agents for cholestatic liver diseases: an overview of their mechanisms of action. Clin Res Hepatol Gastroenterol. 2012;36(Suppl 1):S3–12.
Article CAS PubMed Google Scholar
Oh AR, Bae JS, Lee J, Shin E, Oh BC, Park SC, Cha JY. Ursodeoxycholic acid decreases age-related adiposity and inflammation in mice. BMB Rep. 2016;49:105–10.
留言 (0)