Evolution of SARS-CoV-2 in the murine central nervous system drives viral diversification

Chi, W.-Y. et al. COVID-19 vaccine update: vaccine effectiveness, SARS-CoV-2 variants, boosters, adverse effects, and immune correlates of protection. J. Biomed. Sci. 29, 82 (2022).

Article  PubMed  PubMed Central  Google Scholar 

Hu, B., Guo, H., Zhou, P. & Shi, Z.-L. Characteristics of SARS-CoV-2 and COVID-19. Nat. Rev. Microbiol. 19, 141–154 (2021).

Article  CAS  PubMed  Google Scholar 

Stein, S. R. et al. SARS-CoV-2 infection and persistence in the human body and brain at autopsy. Nature 612, 758–763 (2022).

Article  CAS  PubMed  PubMed Central  Google Scholar 

Hartard, C. et al. Multiorgan and vascular tropism of SARS-CoV-2. Viruses 14, 515 (2022).

Article  CAS  PubMed  PubMed Central  Google Scholar 

Gupta, A. et al. Extrapulmonary manifestations of COVID-19. Nat. Med. 26, 1017–1032 (2020).

Article  CAS  PubMed  Google Scholar 

Jackson, C. B., Farzan, M., Chen, B. & Choe, H. Mechanisms of SARS-CoV-2 entry into cells. Nat. Rev. Mol. Cell Biol. 23, 3–20 (2022).

Article  CAS  PubMed  Google Scholar 

Essalmani, R. et al. Distinctive roles of furin and TMPRSS2 in SARS-CoV-2 infectivity. J. Virol. 96, e00128–22 (2022).

PubMed  PubMed Central  Google Scholar 

Peng, R., Wu, L.-A., Wang, Q., Qi, J. & Gao, G. F. Cell entry by SARS-CoV-2. Trends Biochem. Sci 46, 848–860 (2021).

Article  CAS  PubMed  PubMed Central  Google Scholar 

Jaimes, J. A., Millet, J. K. & Whittaker, G. R. Proteolytic cleavage of the SARS-CoV-2 spike protein and the role of the novel S1/S2 site. iScience 23, 101212 (2020).

Article  CAS  PubMed  PubMed Central  Google Scholar 

Pišlar, A. et al. The role of cysteine peptidases in coronavirus cell entry and replication: the therapeutic potential of cathepsin inhibitors. PLoS Pathog. 16, e1009013 (2020).

Article  PubMed  PubMed Central  Google Scholar 

Davies, N. G. et al. Estimated transmissibility and impact of SARS-CoV-2 lineage B.1.1.7 in England. Science 372, eabg3055 (2021).

Article  CAS  PubMed  PubMed Central  Google Scholar 

Plante, J. A. et al. Spike mutation D614G alters SARS-CoV-2 fitness. Nature 592, 116–121 (2021).

Article  CAS  PubMed  Google Scholar 

Lorenzo-Redondo, R. et al. A clade of SARS-CoV-2 viruses associated with lower viral loads in patient upper airways. EBioMedicine 62, 103112 (2020).

Article  CAS  PubMed  PubMed Central  Google Scholar 

Yuan, S. et al. Pathogenicity, transmissibility, and fitness of SARS-CoV-2 Omicron in Syrian hamsters. Science 377, 428–433 (2022).

Article  CAS  PubMed  Google Scholar 

Korber, B. et al. Tracking changes in SARS-CoV-2 spike: evidence that D614G increases infectivity of the COVID-19 virus. Cell 182, 812–827.e19 (2020).

Article  CAS  PubMed  PubMed Central  Google Scholar 

Lorenzo-Redondo, R., de Sant’Anna Carvalho, A. M., Hultquist, J. F. & Ozer, E. A. SARS-CoV-2 genomics and impact on clinical care for COVID-19. J. Antimicrob. Chemother. 78, ii25–ii36 (2023).

Article  PubMed  PubMed Central  Google Scholar 

Carabelli, A. M. et al. SARS-CoV-2 variant biology: immune escape, transmission and fitness. Nat. Rev. Microbiol. 21, 162–177 (2023).

CAS  PubMed  PubMed Central  Google Scholar 

Yurkovetskiy, L. et al. Structural and functional analysis of the D614G SARS-CoV-2 spike protein variant. Cell 183, 739–751.e8 (2020).

Article  CAS  PubMed  PubMed Central  Google Scholar 

Hou, Y. J. et al. SARS-CoV-2 D614G variant exhibits efficient replication ex vivo and transmission in vivo. Science 370, 1464–1468 (2020).

Article  CAS  PubMed  PubMed Central  Google Scholar 

Liu, Y. et al. Delta spike P681R mutation enhances SARS-CoV-2 fitness over alpha variant. Cell Rep. 39, 110829 (2022).

Article  CAS  PubMed  PubMed Central  Google Scholar 

Chan, Y. A. & Zhan, S. H. The emergence of the spike furin cleavage site in SARS-CoV-2. Mol. Biol. Evol. 39, msab327 (2022).

Article  CAS  PubMed  Google Scholar 

Liu, S. et al. The PRRA insert at the S1/S2 site modulates cellular tropism of SARS-CoV-2 and ACE2 usage by the closely related Bat RaTG13. J. Virol. 95, e01751-20 (2021).

Article  PubMed  PubMed Central  Google Scholar 

Johnson, B. A. et al. Loss of furin cleavage site attenuates SARS-CoV-2 pathogenesis. Nature 591, 293–299 (2021).

Article  CAS  PubMed  PubMed Central  Google Scholar 

Dangi, T., Class, J., Palacio, N., Richner, J. M. & Penaloza MacMaster, P. Combining spike- and nucleocapsid-based vaccines improves distal control of SARS-CoV-2. Cell Rep. 36, 109664 (2021).

Article  CAS  PubMed  PubMed Central  Google Scholar 

Dangi, T. et al. Improved control of SARS-CoV-2 by treatment with a nucleocapsid-specific monoclonal antibody. J. Clin. Invest. 132, e162282 (2022).

Article  CAS  PubMed  PubMed Central  Google Scholar 

Dangi, T. et al. Pre-existing immunity modulates responses to mRNA boosters. Cell Rep. 42, 112167 (2023).

Article  CAS  PubMed  PubMed Central  Google Scholar 

Sanchez, S., Palacio, N., Dangi, T., Ciucci, T. & Penaloza-MacMaster, P. Fractionating a COVID-19 Ad5-vectored vaccine improves virus-specific immunity. Sci. Immunol. 6, eabi8635 (2021).

Dangi, T. et al. Cross-protective immunity following coronavirus vaccination and coronavirus infection. J. Clin. Invest. 131, e151969 (2021).

Article  CAS  PubMed  PubMed Central  Google Scholar 

Ke, R. et al. Longitudinal analysis of SARS-CoV-2 vaccine breakthrough infections reveals limited infectious virus shedding and restricted tissue distribution. Open Forum Infect. Dis. 9, ofac192 (2022).

Article  PubMed  PubMed Central  Google Scholar 

Simons, L. M. et al. Assessment of virological contributions to COVID-19 outcomes in a longitudinal cohort of hospitalized adults. Open Forum Infect. Dis. 9, ofac027 (2022).

Article  PubMed  PubMed Central  Google Scholar 

Simons, L. M. et al. De novo emergence of SARS-CoV-2 spike mutations in immunosuppressed patients. Transpl. Infect. Dis. 24, e13914 (2022).

Article  CAS  PubMed 

留言 (0)

沒有登入
gif