H. Sung, J. Ferlay, R.L. Siegel, M. Laversanne, I. Soerjomataram, A. Jemal, F. Bray, CA Cancer J. Clin. 71, 209–249 (2021). https://doi.org/10.3322/caac.21660

E.C. Smyth, M. Nilsson, H.I. Grabsch, N.C. van Grieken, F. Lordick, Lancet 396, 635–648 (2020). https://doi.org/10.1016/S0140-6736(20)31288-5

M. Alsina, V. Arrazubi, M. Diez, J. Tabernero, Nat. Rev. Gastroenterol. Hepatol. 20, 155–170 (2023). https://doi.org/10.1038/s41575-022-00703-w

M. Zulfiqar, J. Koen, S. Nougaret, C. Bolan, W. VanBuren, M. McGettigan, C. Menias, AJR Am. J. Roentgenol. 215, 1020–1029 (2020). https://doi.org/10.2214/AJR.19.22184

H. Xie, B.J. Erickson, S.P. Sheedy, J. Yin, J.M. Hubbard, J. Gastrointest. Oncol. 12, 226–236 (2021). https://doi.org/10.21037/jgo-20-364

R. Lionetti, M. De Luca, A. Travaglino, A. Raffone, L. Insabato, G. Saccone, M. Mascolo, M. D’Armiento, F. Zullo, F. Corcione, Arch. Gynecol. Obstet. 300, 15–23 (2019). https://doi.org/10.1007/s00404-019-05167-z

J. Wang, Y.K. Shi, L.Y. Wu, J.W. Wang, S. Yang, J.L. Yang, H.Z. Zhang, S.M. Liu, Int. J. Gynecol. Cancer. 18, 825–832 (2008). https://doi.org/10.1111/j.1525-1438.2007.01078.x

H.K. Kim, D.S. Heo, Y.J. Bang, N.K. Kim, Gynecol. Oncol. 82, 105–109 (2001). https://doi.org/10.1006/gyno.2001.6210

V. Kumar, K. Ramnarayanan, R. Sundar, N. Padmanabhan, S. Srivastava, M. Koiwa, T. Yasuda, V. Koh, K.K. Huang, S.T. Tay, S.W.T. Ho, A.L.K. Tan, T. Ishimoto, G. Kim, A. Shabbir, Q. Chen, B. Zhang, S. Xu, K.P. Lam, H.Y.J. Lum, M. Teh, W.P. Yong, J.B.Y. So, P. Tan, Cancer Discov. 12, 670–691 (2022). https://doi.org/10.1158/2159-8290.CD-21-0683

Y. Li, X. Hu, R. Lin, G. Zhou, L. Zhao, D. Zhao, Y. Zhang, W. Li, Y. Zhang, P. Ma, H. Ren, X. Liao, P. Niu, T. Wang, X. Zhang, W. Wang, R. Gao, Q. Li, G. Church, J. He, Y. Chen, Theranostics. 12, 3818–3833 (2022). https://doi.org/10.7150/thno.71833

Y. Sun, S. Chen, Y. Lu, Z. Xu, W. Fu, W. Yan, Commun. Biol. 7, 63 (2024). https://doi.org/10.1038/s42003-024-05765-x

X. Wang, X. Shi, H. Lu, C. Zhang, X. Li, T. Zhang, J. Shen, J. Wen, Adv. Sci. (Weinh) 9, e2200546 (2022) https://doi.org/10.1002/advs.202200546

A. Sathe, S.M. Grimes, B.T. Lau, J. Chen, C. Suarez, R.J. Huang, G. Poultsides, H.P. Ji, Clin. Cancer Res. 26, 2640–2653 (2020). https://doi.org/10.1158/1078-0432.CCR-19-3231

P. Zhang, M. Yang, Y. Zhang, S. Xiao, X. Lai, A. Tan, S. Du, S. Li, Cell. Rep. 27, 1934–1947 (2019). https://doi.org/10.1016/j.celrep.2019.04.052

K. Sun, R. Xu, F. Ma, N. Yang, Y. Li, X. Sun, P. Jin, W. Kang, L. Jia, J. Xiong, H. Hu, Y. Tian, X. Lan, Nat. Commun. 13, 4943 (2022). https://doi.org/10.1038/s41467-022-32627-z

B. Kang, J. Camps, B. Fan, H. Jiang, M.M. Ibrahim, X. Hu, S. Qin, D. Kirchhoff, D.Y. Chiang, S. Wang, Y. Ye, Z. Shen, Z. Bu, Z. Zhang, H.G. Roider, Genome Biol. 23, 265 (2022). https://doi.org/10.1186/s13059-022-02828-2

R. Wang, S. Song, J. Qin, K. Yoshimura, F. Peng, Y. Chu, Y. Li, Y. Fan, J. Jin, M. Dang, E. Dai, G. Pei, G. Han, D. Hao, Y. Li, D. Chatterjee, K. Harada, M.P. Pizzi, A.W. Scott, G. Tatlonghari, X. Yan, Z. Xu, C. Hu, S. Mo, N. Shanbhag, Y. Lu, M. Sewastjanow-Silva, A.A. Fouad Abdelhakeem, G. Peng, S.M. Hanash, G.A. Calin, C. Yee, P. Mazur, A.N. Marsden, A. Futreal, Z. Wang, X. Cheng, J.A. Ajani, L. Wang, Cancer Cell. 41, 1407–1426 (2023). https://doi.org/10.1016/j.ccell.2023.06.005

Y. Hao, S. Hao, E. Andersen-Nissen, W.M. Mauck 3rd, S. Zheng, A. Butler, M.J. Lee, A.J. Wilk, C. Darby, M. Zager, P. Hoffman, M. Stoeckius, E. Papalexi, E.P. Mimitou, J. Jain, A. Srivastava, T. Stuart, L.M. Fleming, B. Yeung, A.J. Rogers, J.M. McElrath, C.A. Blish, R. Gottardo, P. Smibert, R. Satija, Cell 184, 3573–3587 (2021). https://doi.org/10.1016/j.cell.2021.04.048

T. Wu, E. Hu, S. Xu, M. Chen, P. Guo, Z. Dai, T. Feng, L. Zhou, W. Tang, L. Zhan, X. Fu, S. Liu, X. Bo, G. Yu, Innovation (Camb). 2, 100141 (2021). https://doi.org/10.1016/j.xinn.2021.100141

Z. Tang, B. Kang, C. Li, T. Chen, Z. Zhang, Nucleic Acids Res. 47, W556-W560 (2019). https://doi.org/10.1093/nar/gkz430

S. Jin, C.F. Guerrero-Juarez, L. Zhang, I. Chang, R. Ramos, C.H. Kuan, P. Myung, M.V. Plikus, Q. Nie, Nat. Commun. 12, 1088 (2021). https://doi.org/10.1038/s41467-021-21246-9

J. Jiang, Y. Ding, M. Wu, X. Lyu, H. Wang, Y. Chen, H. Wang, L. Teng, Front. Oncol. 10, 1765 (2020). https://doi.org/10.3389/fonc.2020.01765

J. Lu, Y. Peng, R. Huang, Z. Feng, Y. Fan, H. Wang, Z. Zeng, Y. Ji, Y. Wang, Z. Wang, BMC Cancer. 21, 723 (2021). https://doi.org/10.1186/s12885-021-08456-6

L. Li, Z. Huang, K. Du, X. Liu, C. Li, D. Wang, Y. Zhang, C. Wang, J. Li, Front. Pharmacol. 13, 900699 (2022). https://doi.org/10.3389/fphar.2022.900699

R. Fristedt, D. Borg, C. Hedner, J. Berntsson, B. Nodin, J. Eberhard, P. Micke, K. Jirström, J. Gastrointest. Oncol. 7, 848–859 (2016). https://doi.org/10.21037/jgo.2016.11.07

M. Kanda, C. Tanaka, D. Kobayashi, H. Tanaka, D. Shimizu, M. Shibata, H. Takami, M. Hayashi, N. Iwata, Y. Niwa, S. Yamada, T. Fujii, G. Nakayama, M. Fujiwara, Y. Kodera, Int. J. Cancer. 139, 2290–2298 (2016). https://doi.org/10.1002/ijc.30286

H. Wang, J. Min, Y. Ding, Z. Yu, Y. Zhou, S. Wang, A. Gong, M. Xu, Biol. Proced. Online. 26, 1 (2024). https://doi.org/10.1186/s12575-023-00228-9

J. Xu, Y. Fang, K. Chen, S. Li, S. Tang, Y. Ren, Y. Cen, W. Fei, B. Zhang, Y. Shen, W. Lu, Clin. Cancer Res. 28, 3590–3602 (2022). https://doi.org/10.1158/1078-0432.CCR-22-0296

R. Kanaan, M. Medlej-Hashim, R. Jounblat, B. Pilecki, G.L. Sorensen, Matrix Biol. 111, 1–25 (2022). https://doi.org/10.1016/j.matbio.2022.05.008

F. Demarchi, C. Bertoli, T. Copetti, E.L. Eskelinen, C. Schneider, Autophagy. 3, 235–237 (2007). https://doi.org/10.4161/auto.3661

R. Wang, M. Dang, K. Harada, G. Han, F. Wang, M. Pool Pizzi, M. Zhao, G. Tatlonghari, S. Zhang, D. Hao, Y. Lu, S. Zhao, B.D. Badgwell, M. Blum Murphy, N. Shanbhag, J.S. Estrella, S. Roy-Chowdhuri, A.A.F. Abdelhakeem, Y. Wang, G. Peng, S. Hanash, G.A. Calin, X. Song, Y. Chu, J. Zhang, M. Li, K. Chen, A.J. Lazar, A. Futreal, S. Song, J.A. Ajani, L. Wang, Nat. Med. 27, 141–151 (2021). https://doi.org/10.1038/s41591-020-1125-8

Y. Qian, E. Zhai, S. Chen, Y. Liu, Y. Ma, J. Chen, J. Liu, C. Qin, Q. Cao, J. Chen, S. Cai, Int. J. Cancer. 151, 1367–1381 (2022). https://doi.org/10.1002/ijc.34172

H. Jiang, D. Yu, P. Yang, R. Guo, M. Kong, Y. Gao, X. Yu, X. Lu, X. Fan, Clin. Transl Med. 12, e730 (2022). https://doi.org/10.1002/ctm2.730

B. Kutryb-Zajac, G. Harasim, A. Jedrzejewska, O. Krol, A. Braczko, P. Jablonska, P. Mierzejewska, J. Zielinski, E.M. Slominska, R.T. Smolenski, Int. J. Mol. Sci. 22 (2021). https://doi.org/10.3390/ijms22073764

W. Li, X. Zhang, F. Wu, Y. Zhou, Z. Bao, H. Li, P. Zheng, S. Zhao, Cell. Death Dis. 10, 918 (2019). https://doi.org/10.1038/s41419-019-2131-y

K.E. de Visser, J.A. Joyce, Cancer Cell. 41, 374–403 (2023). https://doi.org/10.1016/j.ccell.2023.02.016

C. Rupp, M. Scherzer, A. Rudisch, C. Unger, C. Haslinger, N. Schweifer, M. Artaker, H. Nivarthi, R. Moriggl, M. Hengstschlager, D. Kerjaschki, W. Sommergruber, H. Dolznig, P. Garin-Chesa, Oncogene 34, 815–825 (2015). https://doi.org/10.1038/onc.2014.18

Y.M. Li, Y. Pan, Y. Wei, X. Cheng, B.P. Zhou, M. Tan, X. Zhou, W. Xia, G.N. Hortobagyi, D. Yu, M.C. Hung, Cancer Cell. 6, 459–469 (2004). https://doi.org/10.1016/j.ccr.2004.09.027

D.D. Cave, X. Hernando-Momblona, M. Sevillano, G. Minchiotti, E. Lonardo, Theranostics. 11, 5686–5699 (2021). https://doi.org/10.7150/thno.54027

J.A. Burger, T.J. Kipps, Blood 107, 1761–1767 (2006). https://doi.org/10.1182/blood-2005-08-3182

A. Costa, Y. Kieffer, A. Scholer-Dahirel, F. Pelon, B. Bourachot, M. Cardon, P. Sirven, I. Magagna, L. Fuhrmann, C. Bernard, C. Bonneau, M. Kondratova, I. Kuperstein, A. Zinovyev, A.M. Givel, M.C. Parrini, V. Soumelis, A. Vincent-Salomon, F. Mechta-Grigoriou, Cancer Cell. 33, 463–479 (2018). https://doi.org/10.1016/j.ccell.2018.01.011

A. Zakrzewska, C. Cui, O.W. Stockhammer, E.L. Benard, H.P. Spaink, A.H. Meijer, Blood 116, e1–11 (2010). https://doi.org/10.1182/blood-2010-01-262873

A. Mohammadi, G.L. Sorensen, B. Pilecki, Cells 11, (2022) https://doi.org/10.3390/cells11132115

B.P. Fairfax, F.O. Vannberg, J. Radhakrishnan, H. Hakonarson, B.J. Keating, A.V. Hill, J.C. Knight, Hum. Mol. Genet. 19, 720–730 (2010). https://doi.org/10.1093/hmg/ddp530

C. Yi, W. Wu, D. Zheng, G. Peng, H. Huang, Z. Shen, X. Teng, Cell. Death Dis. 11, 533 (2020). https://doi.org/10.1038/s41419-020-02737-x