Chau NG, Hurwitz S, Mitchell CM, Aserlind A, Grunfeld N, Kaplan L, Hsi P, Bauer DE, Lathan CS, Rodriguez-Galindo C, Tishler RB, Haddad RI, Sallan SE, Bradner JE, French CA (2016) Intensive treatment and survival outcomes in NUT midline carcinoma of the head and neck. Cancer 122(23):3632–3640

Article  PubMed  Google Scholar 

Stevens TM, Morlote D, Xiu J, Swensen J, Brandwein-Weber M, Miettinen MM, Gatalica Z, Bridge JA (2019) NUTM1-rearranged neoplasia: a multi-institution experience yields novel fusion partners and expands the histologic spectrum. Mod Pathol 32(6):764–773

Article  CAS  PubMed  PubMed Central  Google Scholar 

Kubonishi I, Takehara N, Iwata J, Sonobe H, Ohtsuki Y, Abe T, Miyoshi I (1991) Novel t(15;19) (q15;p13) chromosome abnormality in a thymic carcinoma. Cancer Res 51(12):3327–3328

CAS  PubMed  Google Scholar 

Polsani A, Braithwaite KA, Alazraki AL, Abramowsky C, Shehata BM (2012) NUT midline carcinoma: an imaging case series and review of literature. Pediatr Radiol 42(2):205–210

Article  PubMed  Google Scholar 

French CA, Kutok JL, Faquin WC et al (2004) Midline carcinoma of children and young adults with NUT rearrangement. J Clin Oncol 22(20):4135–4139

Article  CAS  PubMed  Google Scholar 

Saik WN, Da Forno P, Thway K, Khurram SA (2021) NUT carcinoma arising from the parotid gland: a case report and review of the literature. Head Neck Pathol 15(3):1064–1068

Article  PubMed  Google Scholar 

Mertens F, Wiebe T, Adlercreutz C, Mandahl N, French CA (2007) Successful treatment of a child with t (15;19)-positive tumor. Pediatr Blood Cancer 49(7):1015–1017

Article  PubMed  Google Scholar 

Yang F, Shen D, Shi J (2021) Primary renal NUT carcinoma identified by next-generation sequencing: a case report and literature review. Int J Clin Exp Pathol 14(5):662–669

CAS  PubMed  PubMed Central  Google Scholar 

Shehata BM, Steelman CK, Abramowsky CR, Olson TA, French CA, Saxe DF, Ricketts RR, Katzenstein HM (2010) NUT midline carcinoma in a newborn with multiorgan disseminated tumor and a 2-year-old with a pancreatic/hepatic primary. Pediatr Dev Pathol 13(6):481–485

Article  PubMed  Google Scholar 

Lemelle L, Pierron G, Fréneaux P, Huybrechts S, Spiegel A, Plantaz D, Julieron M, Dumoucel S, Italiano A, Millot F, Le Tourneau C, Leverger G, Chastagner P, Carton M, Orbach D (2017) NUT carcinoma in children and adults: a multicenter retrospective study. Pediatr Blood Cancer. https://doi.org/10.1002/pbc.26693

Article  PubMed  Google Scholar 

Lauer UM, Hinterleitner M, Horger M, Ohnesorge PV, Zender L (2022) NUT Carcinoma-An Underdiagnosed Malignancy. Front Oncol 26(12):914031

Article  Google Scholar 

Wang L, Zhu Z, Wang W, Zha Y, Wang X, Surita A, Liu Y, Lv W (2023) Sinonasal NUT carcinoma: a retrospective case series from a single institution. Front Surg 1(10):1098704

Article  Google Scholar 

Chau NG, Ma C, Danga K, Al-Sayegh H, Nardi V, Barrette R, Lathan CS, DuBois SG, Haddad RI, Shapiro GI, Sallan SE, Dhar A, Nelson JJ, French CA (2019) An Anatomical Site and Genetic-Based Prognostic Model for Patients With Nuclear Protein in Testis (NUT) Midline Carcinoma: Analysis of 124 Patients. JNCI Cancer Spectr 4(2):pkz094

Article  PubMed  PubMed Central  Google Scholar 

Salati M, Baldessari C, Bonetti LR, Messina C, Merz V, Cerbelli B, Botticelli A (2019) NUT midline carcinoma: Current concepts and future perspectives of a novel tumour entity. Crit Rev Oncol Hematol 144:102826

Article  PubMed  Google Scholar 

Harms A, Herpel E, Pfarr N, Penzel R, Heussel CP, Herth FJ, Dienemann H, Weichert W, Warth A (2015) NUT carcinoma of the thorax: Case report and review of the literature. Lung Cancer 90(3):484–491

Article  PubMed  Google Scholar 

French CA, Miyoshi I, Kubonishi I, Grier HE, Perez-Atayde AR, Fletcher JA (2003) BRD4-NUT fusion oncogene: a novel mechanism in aggressive carcinoma. Cancer Res 63(2):304–307

CAS  PubMed  Google Scholar 

Cho YA, Choi YL, Hwang I, Lee K, Cho JH, Han J (2020) Clinicopathological characteristics of primary lung nuclear protein in testis carcinoma: A single-institute experience of 10 cases. Thorac Cancer 11(11):3205–3212

Article  CAS  PubMed  PubMed Central  Google Scholar 

Lee T, Cho J (2020) Baek CH et al Prevalence of NUT carcinoma in head and neck: Analysis of 362 cases with literature review. Head Neck 42(5):924–938

Article  PubMed  Google Scholar 

French CA, Rahman S, Walsh EM, Kühnle S, Grayson AR, Lemieux ME, Grunfeld N, Rubin BP, Antonescu CR, Zhang S, Venkatramani R, Dal Cin P, Howley PM (2014) NSD3-NUT fusion oncoprotein in NUT midline carcinoma: implications for a novel oncogenic mechanism. Cancer Discov 4(8):928–941

Article  CAS  PubMed  PubMed Central  Google Scholar 

Alekseyenko AA, Walsh EM, Zee BM, Pakozdi T, Hsi P, Lemieux ME, Dal Cin P, Ince TA, Kharchenko PV, Kuroda MI, French CA (2017) Ectopic protein interactions within BRD4-chromatin complexes drive oncogenic megadomain formation in NUT midline carcinoma. Proc Natl Acad Sci U S A 114(21):E4184–E4192

Article  CAS  PubMed  PubMed Central  Google Scholar 

Haack H, Johnson LA, Fry CJ, Crosby K, Polakiewicz RD, Stelow EB, Hong SM, Schwartz BE, Cameron MJ, Rubin MA, Chang MC, Aster JC, French CA (2009) Diagnosis of NUT midline carcinoma using a NUT-specific monoclonal antibody. Am J Surg Pathol 33(7):984–991

Article  PubMed  PubMed Central  Google Scholar 

Salles PG, Moura Rde D, Menezes LM, Bacchi CE (2014) Expression of P16 in NUT carcinomas with no association with human papillomavirus (HPV). Appl Immunohistochem Mol Morphol 22(4):262–265

Article  CAS  PubMed  Google Scholar 

Bauer DE, Mitchell CM, Strait KM et al (2012) Clinicopathologic features and long-term outcomes of NUT midline carcinoma. Clin Cancer Res 18(20):5773–5779

Article  PubMed  PubMed Central  Google Scholar 

Thompson LDR, Franchi A (2018) New tumor entities in the 4th edition of the World Health Organization classification of head and neck tumors: Nasal cavity, paranasal sinuses and skull base. Virchows Arch 472(3):315–330

Article  PubMed  Google Scholar 

Bishop JA, Westra WH (2012) NUT midline carcinomas of the sinonasal tract. Am J Surg Pathol 36(8):1216–1221

Article  PubMed  PubMed Central  Google Scholar 

Minato H, Kobayashi E, Nakada S, Kurose N, Tanaka M, Tanaka Y, Suzuki S, Tanioka F, Saikawa Y, Miwa T, Nojima T (2018) Sinonasal NUT carcinoma: clinicopathological and cytogenetic analysis with autopsy findings. Hum Pathol 71:157–165

Article  PubMed  Google Scholar 

Lemelle L, Moya-Plana A, Dumont B, Fresneau B, Laprie A, Claude L, Deneuve S, Cordero C, Pierron G, Couloigner V, Bernard S, Cardoen L, Brisse HJ, Jehanno N, Metayer L, Fréneaux P, Helfre S, Kolb F, Thariat J, Réguerre Y, Orbach D (2022) NUT carcinoma in children, adolescents and young adults [J]. Bull Cancer 109(4):491–504

Article  PubMed  Google Scholar 

Edgar M, Caruso AM, Kim E, Foss RD (2017) NUT Midline Carcinoma of the Nasal Cavity. Head Neck Pathol 11(3):389–392

Article  PubMed  Google Scholar 

Orman G, Masand P, Hicks J, Huisman TAGM, Guillerman RP (2020) Pediatric thoracic mass lesions: Beyond the common. Eur J Radiol Open 7:100240

Article  PubMed  PubMed Central  Google Scholar 

Jimenez C, Stanton E, Kondra K, Nickels EM, Jacob L, Shah R, Hammoudeh JA (2023) NUT carcinoma of the mandible in a child case report and systematic review. Int J Oral Maxillofac Surg 52(3):304–312

Article  CAS  PubMed  Google Scholar 

Sholl LM, Nishino M, Pokharel S, Mino-Kenudson M, French CA, Janne PA, Lathan C (2015) Primary pulmonary NUT midline carcinoma: clinical, radiographic, and pathologic characterizations. J Thorac Oncol 10(6):951–959

Article  PubMed  PubMed Central