Acute analgesic effect of nicotine vaping using three experimental pain induction tasks: a randomized, placebo-controlled laboratory study

Avelar AJ, Akers AT, Baumgard ZJ, Cooper SY, Casinelli GP, Henderson BJ (2019) Why flavored vape products may be attractive: green apple tobacco flavor elicits reward-related behavior, upregulates nAChRs on VTA dopamine neurons, and alters midbrain dopamine and GABA neuron function. Neuropharmacology 158:107729

Article  CAS  PubMed  PubMed Central  Google Scholar 

Bakhshaie J, Ditre JW, Langdon KJ, Asmundson GJ, Paulus DJ, Zvolensky MJ (2016) Pain intensity and smoking behavior among treatment seeking smokers. Psychiatry Res 237:67–71

Article  PubMed  Google Scholar 

Batista PA, de Paula Werner MF, Oliveira EC, Burgos L, Pereira P, da Silva Brum LF, Santos D, A. R. S (2008) Evidence for the involvement of ionotropic glutamatergic receptors on the antinociceptive effect of (–)-linalool in mice. Neurosci Lett 440(3):299–303

Article  CAS  PubMed  Google Scholar 

Benowitz NL, Helen S, G., Liakoni E (2021) Clinical pharmacology of electronic nicotine delivery systems (ENDS): implications for benefits and risks in the promotion of the combusted tobacco endgame. J Clin Pharmacol 61:S18–S36

Article  CAS  PubMed  PubMed Central  Google Scholar 

Berrendero F, Robledo P, Trigo JM, Martín-García E, Maldonado R (2010) Neurobiological mechanisms involved in nicotine dependence and reward: participation of the endogenous opioid system. Neurosci Biobehavioral Reviews 35(2):220–231

Article  CAS  Google Scholar 

Blank MD, Pearson J, Cobb CO, Felicione NJ, Hiler MM, Spindle TR, Breland A (2020) What factors reliably predict electronic cigarette nicotine delivery? Tob Control 29(6):644–651

PubMed  Google Scholar 

Bremmer MP, Campbell AM, Xia K, Tarran R, Girdler SS, Hendershot CS (2023) Effects of nicotine content and preferred flavor on subjective responses to e-cigarettes: a randomized, placebo-controlled laboratory study. Nicotine Tob Res, ntad143

Bruehl S, Morris MC, Al’Absi M (2022) Stress-induced analgesia: an evaluation of effects on temporal summation of pain and the role of endogenous opioid mechanisms. Pain Rep, 7(2)

Carpenter MJ, Upadhyaya HP, LaRowe SD, Saladin ME, Brady KT (2006) Menstrual cycle Phase effects on nicotine withdrawal and cigarette craving: a review. Nicotine Tob Res 8(5):627–638. https://doi.org/10.1080/14622200600910793

Article  CAS  PubMed  Google Scholar 

Chaudhri N, Caggiula AR, Donny EC, Booth S, Gharib MA, Craven LA, Allen SS, Sved AF, Perkins KA (2005) Sex differences in the contribution of nicotine and nonpharmacological stimuli to nicotine self-administration in rats. Psychopharmacology 180:258–266

Article  CAS  PubMed  Google Scholar 

Cobb CO, Lopez AA, Soule EK, Yen MS, Rumsey H, Scholtes L, Rudy R, Lipato AK, Guy T, M., Eissenberg T (2019) Influence of electronic cigarette liquid flavors and nicotine concentration on subjective measures of abuse liability in young adult cigarette smokers. Drug Alcohol Depend 203:27–34. https://doi.org/10.1016/j.drugalcdep.2019.05.024

Article  CAS  PubMed  PubMed Central  Google Scholar 

Cooper SY, Akers AT, Henderson BJ (2020) Green apple e-cigarette flavorant farnesene triggers reward-related behavior by promoting high-sensitivity nAChRs in the ventral tegmental area. eNeuro, 7(4)

Cordero-Erausquin M, Pons S, Faure P, Changeux J-P (2004) Nicotine differentially activates inhibitory and excitatory neurons in the dorsal spinal cord. Pain 109(3):308–318

Article  CAS  PubMed  Google Scholar 

Dawkins L, Turner J, Roberts A, Soar K (2013) Vaping’profiles and preferences: an online survey of electronic cigarette users. Addiction 108(6):1115–1125. https://onlinelibrary.wiley.com/doi/https://doi.org/10.1111/add.12150

Article  PubMed  Google Scholar 

Dawkins L, Cox S, Goniewicz M, McRobbie H, Kimber C, Doig M, Kośmider L (2018) Real-world’compensatory behaviour with low nicotine concentration e‐liquid: subjective effects and nicotine, acrolein and formaldehyde exposure. Addiction 113(10):1874–1882

Article  PubMed  PubMed Central  Google Scholar 

Decker MW, Rueter LE, Bitner RS (2004) Nicotinic acetylcholine receptor agonists: a potential new class of analgesics. Curr Top Med Chem 4(3):369–384

Article  CAS  PubMed  Google Scholar 

Ditre JW, Brandon TH (2008) Pain as a motivator of smoking: effects of pain induction on smoking urge and behavior. J Abnorm Psychol 117(2):467

Article  PubMed  PubMed Central  Google Scholar 

Ditre JW, Heckman BW, Butts EA, Brandon TH (2010) Effects of expectancies and coping on pain-induced motivation to smoke. J Abnorm Psychol 119(3):524

Article  PubMed  PubMed Central  Google Scholar 

Ditre JW, Brandon TH, Zale EL, Meagher MM (2011) Pain, nicotine, and smoking: research findings and mechanistic considerations. Psychol Bull 137(6):1065

Article  PubMed  PubMed Central  Google Scholar 

Ditre JW, Heckman BW, Zale EL, Kosiba JD, Maisto SA (2016) Acute analgesic effects of nicotine and tobacco in humans: a meta-analysis. Pain 157(7):1373. https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4912401/pdf/nihms-774195.pdf

Article  CAS  PubMed  PubMed Central  Google Scholar 

Ditre JW, Zale EL, LaRowe LR (2019) A reciprocal model of pain and substance use: transdiagnostic considerations, clinical implications, and future directions. Ann Rev Clin Psychol 15:503–528

Article  Google Scholar 

Donny E, Caggiula A, Rowell P, Gharib M, Maldovan V, Booth S, Mielke M, Hoffman A, McCallum S (2000) Nicotine self-administration in rats: estrous cycle effects, sex differences and nicotinic receptor binding. Psychopharmacology 151:392–405

Article  CAS  PubMed  Google Scholar 

Etter J-F (2016) A longitudinal study of cotinine in long-term daily users of e-cigarettes. Drug Alcohol Depend 160:218–221

Article  CAS  PubMed  Google Scholar 

Fertig JB, Pomerleau OF, Sanders B (1986) Nicotine-produced antinociception in minimally deprived smokers and ex-smokers. Addict Behav 11(3):239–248

Article  CAS  PubMed  Google Scholar 

Frid M, Singer G, Rana C (1979) Interactions between personal expectations and naloxone: effects on tolerance to ischemic pain. Psychopharmacology 65:225–231

Article  CAS  PubMed  Google Scholar 

Genzen JR, McGehee DS (2005) Nicotinic modulation of GABAergic synaptic transmission in the spinal cord dorsal horn. Brain Res 1031(2):229–237

Article  CAS  PubMed  Google Scholar 

Girdler SS, Maixner W, Naftel HA, Stewart PW, Moretz RL, Light KC (2005) Cigarette smoking, stress-induced analgesia and pain perception in men and women. Pain 114(3):372–385. https://doi.org/10.1016/j.pain.2004.12.035

Article  PubMed  Google Scholar 

Goldenson NI, Kirkpatrick MG, Barrington-Trimis JL, Pang RD, McBeth JF, Pentz MA, Samet JM, Leventhal AM (2016) Effects of sweet flavorings and nicotine on the appeal and sensory properties of e-cigarettes among young adult vapers: application of a novel methodology. Drug Alcohol Depend 168:176–180. https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5086287/pdf/nihms818759.pdf

Article  CAS  PubMed  PubMed Central  Google Scholar 

Goldenson NI, Augustson EM, Chen J, Shiffman S (2022) Pharmacokinetic and subjective assessment of prototype JUUL2 electronic nicotine delivery system in two nicotine concentrations, JUUL system, IQOS, and combustible cigarette. Psychopharmacology 239(3):977–988

Article  CAS  PubMed  PubMed Central  Google Scholar 

Grevert P, Goldstein A (1977) Effects of naloxone on experimentally induced ischemic pain and on mood in human subjects. Proc Natl Acad Sci 74(3):1291–1294

Article  CAS  PubMed  PubMed Central  Google Scholar 

Hahn EJ, Rayens MK, Kirsh KL, Passik SD (2006) Brief report: Pain and readiness to quit smoking cigarettes. Nicotine Tob Res 8(3):473–480

Article  PubMed  Google Scholar 

Hartmann-Boyce J, Lindson N, Butler AR, McRobbie H, Bullen C, Begh R, Theodoulou A, Notley C, Rigotti NA, Turner T (2022) Electronic cigarettes for smoking cessation. Cochrane Database Syst Reviews (11).

Heatherton TF, Kozlowski LT, Frecker RC, Fagerstrom KO (1991) The Fagerstrom Test for Nicotine Dependence: a revision of the Fagerstrom Tolerance Questionnaire. Br J Addict 86(9):1119–1127. https://doi.org/10.1111/j.1360-0443.1991.tb01879.x

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