O'Neill, L. A., Kishton, R. J. & Rathmell, J. A guide to immunometabolism for immunologists. Nat. Rev. Immunol. 16, 553–565 (2016).
Article CAS PubMed PubMed Central Google Scholar
Stifel, U. et al. Glucocorticoids coordinate macrophage metabolism through the regulation of the tricarboxylic acid cycle. Mol. Metab. 57, 101424 (2022).
Article CAS PubMed Google Scholar
Auger, J.-P. et al. Metabolic rewiring promotes anti-inflammatory effects of glucocorticoids. Nature 629, 184–192 (2024).
Article CAS PubMed Google Scholar
Jones, C. G., Hothi, S. K. & Titheradge, M. A. Effect of dexamethasone on gluconeogenesis, pyruvate kinase, pyruvate carboxylase and pyruvate dehydrogenase flux in isolated hepatocytes. Biochem. J. 289, 821–828 (1993).
Article CAS PubMed PubMed Central Google Scholar
Martin, A. D., Allan, E. H. & Titheradge, M. A. The stimulation of mitochondrial pyruvate carboxylation after dexamethasone treatment of rats. Biochem. J. 219, 107–115 (1984).
Article CAS PubMed PubMed Central Google Scholar
Franco, L. M. et al. Immune regulation by glucocorticoids can be linked to cell type-dependent transcriptional responses. J. Exp. Med. 216, 384–406 (2019).
Article CAS PubMed PubMed Central Google Scholar
Hong, S. G. et al. Glucocorticoid-induced eosinopenia results from CXCR4-dependent bone marrow migration. Blood 136, 2667–2678 (2020).
Article PubMed PubMed Central Google Scholar
Grøntved, L. et al. C/EBP maintains chromatin accessibility in liver and facilitates glucocorticoid receptor recruitment to steroid response elements. EMBO J. 32, 1568–1583 (2013).
Article PubMed PubMed Central Google Scholar
Medetgul-Ernar, K. & Davis, M. M. Standing on the shoulders of mice. Immunity 55, 1343–1353 (2022).
留言 (0)