Papa S, Choy PM, Bubici C. The ERK and JNK pathways in the regulation of metabolic reprogramming. Oncogene. 2019;38(13):2223–40.

Article  CAS  PubMed  Google Scholar 

Dimeloe S, Burgener A-V, Grählert J, Hess C. T-cell metabolism governing activation, proliferation and differentiation; a modular view. Immunology. 2017;150(1):35–44.

Article  CAS  PubMed  Google Scholar 

Sanchez EL, Lagunoff M. Viral activation of cellular metabolism. Virology. 2015;479–80:609–18.

Zhou HC, Xin-Yan Y, Yu WW, Liang XQ, Du XY, Liu ZC, et al. Lactic acid in macrophage polarization: the significant role in inflammation and cancer. Int Rev Immunol. 2022;41(1):4–18.

Article  CAS  PubMed  Google Scholar 

Certo M, Llibre A, Lee W, Mauro C. Understanding lactate sensing and signalling. Trends in endocrinology and metabolism. Trends Endocrinol Metab. 2022;33(10):722–35.

Article  CAS  PubMed  Google Scholar 

Wang Z-H, Peng W-B, Zhang P, Yang X-P, Zhou Q. Lactate in the tumour microenvironment: from immune modulation to therapy. EBioMedicine. 2021;73:103627.

Article  CAS  PubMed  PubMed Central  Google Scholar 

Sebestyén A, Dankó T, Sztankovics D, Moldvai D, Raffay R, Cervi C, et al. The role of metabolic ecosystem in cancer progression — metabolic plasticity and mTOR hyperactivity in tumor tissues. Cancer Metastasis Rev. 2021;40(4):989–1033.

Article  PubMed  Google Scholar 

Thaker SK, Ch’ng J, Christofk HR. Viral hijacking of cellular metabolism. BMC Biol. 2019;17(1):59.

Article  PubMed  PubMed Central  Google Scholar 

Yu L, Chen X, Wang L, Chen S. Oncogenic virus-induced aerobic glycolysis and tumorigenesis. J Cancer. 2018;9(20):3699–706.

Article  PubMed  PubMed Central  Google Scholar 

Moreno-Altamirano MMB, Kolstoe SE, Sánchez-García FJ. Virus Control of Cell metabolism for replication and evasion of host Immune responses. Front Cell Infect Microbiol. 2019;9:95.

Article  CAS  PubMed  PubMed Central  Google Scholar 

Li TY, Yang Y, Zhou G, Tu ZK. Immune suppression in chronic hepatitis B infection associated liver disease: a review. World J Gastroenterol. 2019;25(27):3527–37.

Article  CAS  PubMed  PubMed Central  Google Scholar 

Kocianova E, Piatrikova V, Golias T. Revisiting the Warburg Effect with Focus on Lactate. Cancers. 2022;14(24):6028.

Article  CAS  PubMed  PubMed Central  Google Scholar 

Manoharan I, Prasad PD, Thangaraju M, Manicassamy S. Lactate-dependent regulation of Immune responses by dendritic cells and macrophages. Front Immunol. 2021;12:691134.

Article  CAS  PubMed  PubMed Central  Google Scholar 

Nolt B, Tu F, Wang X, Ha T, Winter R, Williams DL, et al. Lactate and Immunosuppression in Sepsis. Shock. 2018;49(2):120–5.

Article  CAS  PubMed  PubMed Central  Google Scholar 

Van Wilpe S, Koornstra R, Den Brok M, De Groot JW, Blank C, De Vries J, et al. Lactate dehydrogenase: a marker of diminished antitumor immunity. Oncoimmunology. 2020;9(1):1731942.

Article  PubMed  PubMed Central  Google Scholar 

Kondo T, Koroki K, Kanzaki H, Kobayashi K, Kiyono S, Nakamura M, et al. Impact of acute decompensation on the prognosis of patients with hepatocellular carcinoma. PLoS ONE. 2022;17(1):e0261619.

Article  CAS  PubMed  PubMed Central  Google Scholar 

Faloppi L, Bianconi M, Memeo R, Casadei Gardini A, Giampieri R, Bittoni A, et al. Lactate Dehydrogenase in Hepatocellular Carcinoma: something Old, something New. Biomed Res Int. 2016;2016:7196280.

Article  PubMed  PubMed Central  Google Scholar 

Yin J, Xu X, Pu R, Su H, Wang J, Liu W, et al. A Lower HCC incidence in chronic HBV-Infected patients recovered from Acute-on-chronic liver failure: a prospective cohort study. J Oncol. 2022;2022:5873002.

Article  PubMed  PubMed Central  Google Scholar 

Nie Y, Zhang Y, Liu LX, Zhu X. Serum lactate level predicts short-term and long-term mortality of HBV-ACLF patients: a prospective study. Ther Clin Risk Manag. 2020;16:849–60.

Article  PubMed  PubMed Central  Google Scholar 

Yang S, Liu K, Yang L, Xu L, Lu X, Sun X, et al. Value of lactate level in predicting the short-term prognosis of patients with acute-on-chronic hepatitis B liver failure. J Clin Hepatol. 2022;38(7):1482.

CAS  Google Scholar 

Nie Y, Liu LX, Chen T, Zhang Y, Zhu X. Serum lactate level predicts 6-months mortality in patients with hepatitis B virus-related decompensated cirrhosis: a retrospective study. Epidemiol Infect. 2021;149:e26.

Article  CAS  PubMed  PubMed Central  Google Scholar 

Gao F, Huang XL, Cai MX, Lin MT, Wang BF, Wu W, et al. Prognostic value of serum lactate kinetics in critically ill patients with cirrhosis and acute-on-chronic liver failure: a multicenter study. Aging. 2019;11(13):4446–62.

Article  CAS  PubMed  PubMed Central  Google Scholar 

Shokri S, Mahmoudvand S, Taherkhani R, Farshadpour F, Jalalian FA. Complexity on modulation of NF-κB pathways by hepatitis B and C: a double-edged sword in hepatocarcinogenesis. J Cell Physiol. 2019;234:14734–42.

Article  CAS  PubMed  Google Scholar 

Adam A, Fusheini A. Knowledge, risk of infection, and vaccination status of hepatitis B virus among rural high school students in Nanumba North and South districts of Ghana. PLoS ONE. 2020;15(4):e0231930.

Article  CAS  PubMed  PubMed Central  Google Scholar 

Chen H, Wu Q, Peng L, Cao T, Deng M-L, Liu Y-W, et al. Mechanism, clinical significance, and Treatment Strategy of Warburg Effect in Hepatocellular Carcinoma. J Nanomaterials. 2021;2021:5164100.

Article  Google Scholar 

Diaz O, Vidalain PO, Ramière C, Lotteau V, Perrin-Cocon L. What role for cellular metabolism in the control of hepatitis viruses? Front Immunol. 2022;13:1033314.

Article  CAS  PubMed  PubMed Central  Google Scholar 

Yen C-J, Yang S-T, Chen R-Y, Huang W, Chayama K, Lee M-H, et al. Hepatitis B virus X protein (HBx) enhances centrosomal P4.1-associated protein (CPAP) expression to promote hepatocarcinogenesis. J Biomed Sci. 2019;26(1):44.

Article  PubMed  PubMed Central  Google Scholar 

Yoo Y-G, Oh SH, Park ES, Cho H, Lee N, Park H, et al. Hepatitis B Virus X protein enhances transcriptional activity of Hypoxia-inducible Factor-1α through activation of Mitogen-activated protein kinase pathway. J Biol Chem. 2003;278(40):39076–84.

Article  CAS  PubMed  Google Scholar 

Hosios AM, Manning BD. Cancer Signaling drives Cancer Metabolism: AKT and the Warburg Effect. Cancer Res. 2021;81(19):4896–8.

Article  CAS  PubMed  Google Scholar 

Chen L, Lin X, Lei Y, Xu X, Zhou Q, Chen Y, et al. Aerobic glycolysis enhances HBx-initiated hepatocellular carcinogenesis via NF-κBp65/HK2 signalling. J Exp Clin Cancer Res. 2022;41(1):329.

Article  CAS  PubMed  PubMed Central