Mapping Crohn’s Disease Pathogenesis with Mycobacterium paratuberculosis: A Hijacking by a Stealth Pathogen

Yuan F, Zhang Y-H, Kong X-Y, Cai Y-D. Identification of Candidate Genes Related to Inflammatory Bowel Disease Using Minimum Redundancy Maximum Relevance, Incremental Feature Selection, and the Shortest-Path Approach. Biomed Res Int. 2017;2017:5741948.

Article  PubMed  PubMed Central  Google Scholar 

Zheng D, Liwinski T, Elinav E. Interaction between microbiota and immunity in health and disease. Cell Res. 2020;30:492–506.

Article  PubMed  PubMed Central  Google Scholar 

Xu X-R, Liu C-Q, Feng B-S, Liu Z-J. Dysregulation of mucosal immune response in pathogenesis of inflammatory bowel disease. World J Gastroenterol. 2014;20:3255–3264.

Article  CAS  PubMed  PubMed Central  Google Scholar 

Ahluwalia B, Moraes L, Magnusson MK, Öhman L. Immunopathogenesis of inflammatory bowel disease and mechanisms of biological therapies. Scandinavian Journal of Gastroenterology. 2018;53:379–389.

Article  PubMed  Google Scholar 

Ahlawat S, Asha, Sharma KK. Gut–organ axis: a microbial outreach and networking. Letters Applied Microbiology. 2021;72:636–68.

Zuo T, Ng SC. The Gut Microbiota in the Pathogenesis and Therapeutics of Inflammatory Bowel Disease. Front Microbiol. 2018;9:2247.

Article  PubMed  PubMed Central  Google Scholar 

Antoni L, Nuding S, Wehkamp J, Stange EF. Intestinal barrier in inflammatory bowel disease. World J Gastroenterol. 2014;20:1165–1179.

Article  PubMed  PubMed Central  Google Scholar 

Schaubeck M, Clavel T, Calasan J et al. Dysbiotic gut microbiota causes transmissible Crohn’s disease-like ileitis independent of failure in antimicrobial defence. Gut. 2016;65:225–237.

Article  CAS  PubMed  Google Scholar 

Loh G, Blaut M. Role of commensal gut bacteria in inflammatory bowel diseases. Gut Microbes. 2012;3:544–555.

Article  PubMed  PubMed Central  Google Scholar 

Chen J, Chen H, Huang Y, Xie H, Li S, Wang C. Serum food specific IgG antibodies are associated with small bowel inflammation in patients with Crohn’s disease. Eur J Clin Nutr. 2023. https://doi.org/10.1038/s41430-023-01343-2.

Article  PubMed  PubMed Central  Google Scholar 

Ahlawat S, Kumar P, Mohan H, Goyal S, Sharma KK. Inflammatory bowel disease: tri-directional relationship between microbiota, immune system and intestinal epithelium. Crit Rev Microbiol. 2021;47:254–273.

Article  CAS  PubMed  Google Scholar 

Ananthakrishnan AN. Environmental risk factors for inflammatory bowel disease. Gastroenterol Hepatol (N Y). 2013;9:367–374.

PubMed  Google Scholar 

Carrière J, Darfeuille-Michaud A, Nguyen HTT. Infectious etiopathogenesis of Crohn’s disease. World J Gastroenterol. 2014;20:12102–12117.

Article  PubMed  PubMed Central  Google Scholar 

Ghielmetti G, Giger U. Mycobacterium avium: an Emerging Pathogen for Dog Breeds with Hereditary Immunodeficiencies. Curr Clin Microbiol Rep. 2020;7:67–80.

Article  PubMed  PubMed Central  Google Scholar 

Garvey M. Mycobacterium avium subspecies paratuberculosis: A possible causative agent in human morbidity and risk to public health safety. Open Vet J. 2018;8:172.

Article  PubMed  PubMed Central  Google Scholar 

Chamberlin W, Graham DY, Hulten K et al. Mycobacterium avium subsp. paratuberculosis as one cause of Crohn’s disease. Aliment Pharmacol Ther. 2001;15:337–346.

Article  CAS  PubMed  Google Scholar 

Gibson S, Harrison J, Cox J. Modelling a Silent Epidemic: A Review of the In Vitro Models of Latent Tuberculosis. Pathogens. 2018;7:88.

Article  CAS  PubMed  PubMed Central  Google Scholar 

Chandra P, Grigsby SJ, Philips JA. Immune evasion and provocation by Mycobacterium tuberculosis. Nat Rev Microbiol. 2022;20:750–766.

Article  CAS  PubMed  PubMed Central  Google Scholar 

Wayne LG, Sohaskey CD. Nonreplicating persistence of mycobacterium tuberculosis. Annu Rev Microbiol. 2001;55:139–163.

Article  CAS  PubMed  Google Scholar 

Naser SA, Sagramsingh SR, Naser AS, Thanigachalam S. Mycobacterium avium subspecies paratuberculosis causes Crohn’s disease in some inflammatory bowel disease patients. World J Gastroenterol. 2014;20:7403–7415.

Article  PubMed  PubMed Central  Google Scholar 

Fidler HM, Thurrell W, Johnson NM, Rook GA, McFadden JJ. Specific detection of Mycobacterium paratuberculosis DNA associated with granulomatous tissue in Crohn’s disease. Gut. 1994;35:506–510.

Article  CAS  PubMed  PubMed Central  Google Scholar 

Sidoti F, Banche G, Astegiano S, Allizond V, Cuffini AM, Bergallo M. Validation and standardization of IS900 and F57 real-time quantitative PCR assays for the specific detection and quantification of Mycobacterium avium subsp. paratuberculosis. Can J Microbiol. 2011;57:347–354.

Article  CAS  PubMed  Google Scholar 

Agriculture in Manitoba, Canada. Johne’s Disease. Available from: https://www.gov.mb.ca/agriculture/animal-health-and-welfare/animal-health/johnes-disease.html

Bernstein CN, Blanchard JF, Rawsthorne P, Collins MT. Population-based case control study of seroprevalence of Mycobacterium paratuberculosis in patients with Crohn’s disease and ulcerative colitis. J Clin Microbiol. 2004;42:1129–1135.

Article  PubMed  PubMed Central  Google Scholar 

Green C, Elliott L, Beaudoin C, Bernstein CN. A Population-based Ecologic Study of Inflammatory Bowel Disease: Searching for Etiologic Clues. American Journal of Epidemiology. 2006;164:615–623.

Article  PubMed  Google Scholar 

Pickup RW, Rhodes G, Arnott S et al. Mycobacterium avium subsp. paratuberculosis in the catchment area and water of the River Taff in South Wales, United Kingdom, and its potential relationship to clustering of Crohn’s disease cases in the city of Cardiff. Appl Environ Microbiol. 2005;71:2130–2139.

Article  CAS  PubMed  PubMed Central  Google Scholar 

Cousins D, Condron RJ, Eamens Gj, Whittington R, de Lisle GW. Paratuberculosis (Johnes Disease). Australia and New Zealand Standard Diagnostic Procedures. 2002 Available from: https://www.agriculture.gov.au/sites/default/files/sitecollectiondocuments/animal/ahl/ANZSDP-Paratuberculosis-Johnes-disease%5Bsuperseded%5D.pdf

Gearry RB, Richardson A, Frampton CMA, Collett JA, Burt MJ, Chapman BA et al. High incidence of Crohn’s disease in Canterbury, New Zealand: results of an epidemiologic study. Inflamm Bowel Dis. 2006;12:936–943.

Article  PubMed  Google Scholar 

Barta Z, Csipo I, Mekkel G, Zeher M, Majoros L. Seroprevalence of Mycobacterium paratuberculosis in patients with Crohn’s Disease. J Clin Microbiol. 2004;42:5432; author reply 5432–5433.

Singh AV, Singh SV, Singh PK, Sohal JS, Singh MK. High prevalence of Mycobacterium avium subspecies paratuberculosis ('Indian bison type’) in animal attendants suffering from gastrointestinal complaints who work with goat herds endemic for Johne’s disease in India. Int J Infect Dis. 2011;15:e677-683.

Article  CAS  PubMed  Google Scholar 

Fridriksdottir V, Gunnarsson E, Sigurdarson S, Gudmundsdottir KB. Paratuberculosis in Iceland: epidemiology and control measures, past and present. Vet Microbiol. 2000;77:263–267.

Article  CAS  PubMed  Google Scholar 

Hermon-Taylor J, El-Zaatari FAK. Pathogenic Mycobacteria in Water: a guide to Public Health Consequences, Monitoring and Management. London. Pathogenic Mycobacteria in Water: A Guide to Public Health Consequences, Monitoring and Management.". IWA Publishing.; 2004; pp 74–94.

Björnsson S, Tryggvason FÞ, Jónasson JG, et al. Incidence of inflammatory bowel disease in Iceland 1995 - 2009. A nationwide population-based study. Scand J Gastroenterol. 2015;50:1368–75.

Rhodes G, Richardson H, Hermon-Taylor J, Weightman A, Higham A, Pickup R. Mycobacterium avium Subspecies paratuberculosis: Human Exposure through Environmental and Domestic Aerosols. Pathogens. 2014;3:577–595.

Article  PubMed  PubMed Central  Google Scholar 

Mintz MJ, Lukin DJ. Mycobacterium avium subspecies paratuberculosis (MAP) and Crohn’s disease: the debate continues. Transl Gastroenterol Hepatol. 2023;8:28.

Article 

留言 (0)

沒有登入
gif