Memory enhancing and neuroprotective effects of apomorphine in a rat model of dementia

Abdulrahman H, Fletcher PC, Bullmore E, Morcome AM (2017) Dopamine and memory dedifferentiation in aging. Neuroimage 153:211–220

Article  CAS  PubMed  Google Scholar 

Badshah H, Kim TH, Kim MJ, Ahmad A, Kim MO (2014) Apomorphine attenuates ethanol-induced neurodegeneration in the adult rat cortex. Neurochem Int 74:8–15

Article  CAS  PubMed  Google Scholar 

Borgemeester RWK, Van Laar T (2017) Continuous subcutaneous apomorphine infusion in Parkinson’s disease patients with cognitive dysfunction: a retrospective long-term follow-up study. Parkinsonism Relat Disord 45:33–38

Article  PubMed  Google Scholar 

Bradley-Whitman MA, Lovell MA (2015) Biomarkers of lipid peroxidation in Alzheimer disease (AD): an update. Arch Toxicol 89:1035–1044

Article  CAS  PubMed  PubMed Central  Google Scholar 

Burruss JW, Hurley RA, Taber KH, Rauch RA, Norton RE, Hayman LA (2000) Functional neuroanatomy of the frontal lobe circuits. Radiology 214:227–230

Article  CAS  PubMed  Google Scholar 

Castri P, Busceti C, Battaglia G, Girardi F, Cavallari M, Orzi F, Fornai F (2006) Protection by apomorphine in two independent models of acute inhibition of oxidative metabolism in rodents. Clin Exp Hypertens 28:387–394

Article  CAS  PubMed  Google Scholar 

Cheignon C, Tomas M, Bonnefont-Rousselot D, Faller P, Collin F (2018) Oxidative stress and the amyloid beta peptide in Alzheimer’s disease. Redox Biol 14:450–464

Article  CAS  PubMed  Google Scholar 

Chidambara-Murthy KN, Jayaprakasha GK, Singh RP (2002) Studies on antioxidant activity of pomegranate (Punica granatum) peel extract using in vivo models. J Agric Food Chem 50:4791–4795

Article  PubMed  Google Scholar 

Chow CK, Tappel AL (1971) An enzymatic protective mechanism against lipid peroxidation damage to lungs of ozone-exposed rats. Lipids 7:518–524

Article  Google Scholar 

de Mello Bastos JM, Dias FR, Alves VH, Carey RJ, Carrera MP (2014) Drug memory substitution during re-consolidation: a single inhibitory autoreceptor apomorphine treatment given during psychostimulant memory re-consolidation replaces psychostimulant conditioning with conditioned inhibition and reverses psychostimulant sensitization. Behav Brain Res 260:139–147

Article  PubMed  Google Scholar 

Deshmukh R, Kaundal M, Bansal V, Samardeep, (2016) Caffeic acid attenuates oxidative stress, learning and memory deficit in intra-cerebroventricular streptozotocin induced experimental dementia in rats. Biomed Pharmacother 81:56–62

Article  CAS  PubMed  Google Scholar 

Ellman GL, Courtney KD, AndresV FRM (1961) A new and rapid colorimetric determination of acetylcholinesterase activity. Biochem Pharmacol 7:88–95

Article  CAS  PubMed  Google Scholar 

Flatt JD, Gilsanz P, Quesenberry CP, Albers KB, Whitmer RA (2018) Post-traumatic stress disorder and risk of dementia among members of a health care delivery system. Alz Dem 14:28–34

Google Scholar 

Flohe L, Gunzler WA (1984) Assays of glutathione peroxidase. Methods Enzymol 105:114–121

Fornai F, Battaglia G, Gesi M, Orzi F, Ruggieri S (2001) Dose-dependent protective effects of apomorphine against methamphetamine-induced nigrostriatal damage. Brain Res 898:27–35

Article  CAS  PubMed  Google Scholar 

Grunblatt E, Mandel S, Maor G, Youdim MB (2001) Effects of R- and S-apomorphine on MPTP-induced nigro-striatal dopamine neuronal loss. J Neurochem 77:146–156

CAS  PubMed  Google Scholar 

Guadagno NA, Moriconi C, Licursi V, D’Acunto E, Nisi PS, Carucci N, De Jaco A, Cacci E, Negria R, Lupod G, Mirandaae E (2017) Neuroserpin polymers cause oxidative stress in a neuronal model of the dementia FENIB. Neurobiol Dis 103:32–44

Hanaki M, Murakami K, Katayama S, Akagi K-I, Irie K (2018) Mechanistic analyses of the suppression of amyloid β42 aggregation by apomorphine. Bioorg Med Chem. https://doi.org/10.1016/j.bmc.2018.01.028

Article  PubMed  Google Scholar 

Hartl D, Schuldt V, Forler S, Zabel C, Klose J, Rohe M (2012) Presymptomatic alterations in energy metabolism and oxidative stress in the APP23 mouse model of Alzheimer disease. J Prot Res 11:3295–3304

Article  CAS  Google Scholar 

Himeno E, Ohyagi Y, Ma L, Nakamura N, Miyoshi K, Sakae N, Motomura K, Soejima N, Yamasaki R, Hashimoto T, Tabira T, LaFerla FM, Kira J (2011) Apomorphine treatment in Alzheimer mice promoting amyloid-β degradation. Ann Neurol 69:248–256

Article  CAS  PubMed  Google Scholar 

Ikram H, Zakir R, Haleem DJ (2011) Effects of single administration of apomorphine on memory and monoamine metabolism: a dose related study. Pak J Pharm Sci 31:439–445

Google Scholar 

Ikram H, Zakir R, Haleem DJ (2018) Effects of single administration of apomorphine on memory and monoamine metabolism: a dose related study. Pak J Pharm Sci 31(2):439–445

CAS  PubMed  Google Scholar 

Ikram H, Tasneem S, Perveen S, Zakir R, Haleem DJ (2021) Neurochemical and behavioral effects of fluoxetine on midazolam induce dependence in an animal model of addiction. Pak J Pharm Sci 34(5):1749–1757

CAS  PubMed  Google Scholar 

Ikram H, Masood R, Syed S, Haleem DJ (2023) Neuropharmacological studies on repurposed utilization of pioglitazone in learning and memory: a dose related study. Pak J Pharm Sci 36(4):1159–1167

CAS  Google Scholar 

Ikram H, Haleem DJ (2019) Repeated treatment with a low dose of reserpine as a progressive model of Parkinson’s dementia. Pak J Pharm Sci (Impact Factor: 0.95) 32(2):555–562

Jung JH, An K, Kwon OB, Kim H, Kim J-H (2011) Pathway-specific alteration of synaptic plasticity in Tg2576 mice. Mol Cells 32:197–201

Article  CAS  PubMed  PubMed Central  Google Scholar 

Kumar A, Singh N (2017) Inhibitor of Phosphodiestearse-4 improves memory deficits, oxidative stress, neuroinflammation and neuropathological alterations in mouse models of dementia of Alzheimer’s type. Biomed Pharmacoth 88:698–707

Article  CAS  Google Scholar 

Li R, Singh M (2014) Sex differences in cognitive impairment and Alzheimer’s disease. Front Neuroendocrinol 35:385–403

Article  PubMed  PubMed Central  Google Scholar 

Lisman JE, Grace AA (2005) The hippocampal-VTA loop: controlling the entry of information into long-term memory. Neuron 46:703–713

Article  CAS  PubMed  Google Scholar 

Morelira PI, Smith MA, Zhu X, Santos MS, Oliveira CR, Perry G (2004) Therapeutic potential of oxidant mechanisms in Alzheimer’s disease. Expert Rev Neurother 4:995–1004

Article  Google Scholar 

Murakami K, Murata N, Noda Y, Tahara S, Kaneko T, Kinoshita N, Hatsuta H, Murayama S, Barnham KJ, Irie K, Shirasawa T, Shimizu T (2011) OD1 (Copper/Zinc Superoxide Dismutase) deficiency drives amyloid β protein oligomerization and memory loss in mouse model of alzheimer disease. J Biol Chem 286:44557–44568

Article  CAS  PubMed  PubMed Central  Google Scholar 

Neugroschl J, Wang S (2011) Alzheimer’s disease: diagnosis and treatment across the spectrum of disease severity. Mt Sinai J Med 78:596–612

Article  PubMed  PubMed Central  Google Scholar 

Nobili A, Latagliata EC, Viscomi MT, Cavallucci V, Cutuli D, Giacovazzo G, Krashia P, Rizzo FR, Marino R, Federici M, De Bartolo P, Aversa D, Dell’Acqua MC, Cordella A, Sancandi M, Keller F, Petrosini L, Puglisi-Allegra S, Mercuri NB, Coccurello R, Berretta N, D’Amelio M (2017) Dopamine neuronal loss contributes to memory and reward dysfunction in a model of Alzheimer’s disease. Nature Comm. https://doi.org/10.1038/ncomms14727

Article  Google Scholar 

Pinheiro M, Carey RJ, Cruz Dias FR, de Mattos LW (2012) Memory re-consolidation and drug conditioning: an apomorphine conditioned locomotor stimulant response can be enhanced or reversed by a single high versus low apomorphine post-trial treatment. Psychopharmacology 220:281–291

Article  Google Scholar 

Riedel G, Kang SH, Choi DY, Platt B (2009) Scopolamine-induced deficits in social memory in mice: reversal by donepezil. Behav Brain Res 204:217–225

Article  CAS  PubMed  Google Scholar 

Rosa-Grilo M, Qamar MA, As E, Chaudhuri KR (2016) The efficacy of apomorphine – a non-motor perspective. Park Rel Disord 33:28–35

Article  Google Scholar 

Sandhir R, Yadav A, Sunkaria A, Singhal N (2015). Nano-antioxidants: An emerging strategy for intervention against neurodegenerative conditions. Neurochem Int 89(1): 209–226

留言 (0)

沒有登入
gif