Lounis Y, Hugo J, Demarche M, Seghaye M-C (2020) Influence of age on clinical presentation, diagnosis delay and outcome in pre-school children with acute appendicitis. BMC Pediatr 20:151. https://doi.org/10.1186/s12887-020-02053-5

Article  PubMed  PubMed Central  Google Scholar 

Pátková B, Svenningsson A, Almström M et al (2023) Long-term outcome of nonoperative treatment of appendicitis. JAMA Surg 158:1105–1106. https://doi.org/10.1001/jamasurg.2023.2756

Article  PubMed  Google Scholar 

Patkova B, Svenningsson A, Almström M et al (2020) Nonoperative treatment versus appendectomy for acute nonperforated appendicitis in children: five-year follow up of a randomized controlled pilot trial. Ann Surg 271:1030–1035. https://doi.org/10.1097/SLA.0000000000003646

Article  PubMed  Google Scholar 

Skjold-Ødegaard B, Søreide K (2022) The diagnostic differentiation challenge in acute appendicitis: how to distinguish between uncomplicated and complicated appendicitis in adults. Diagnostics (Basel) 12:1724. https://doi.org/10.3390/diagnostics12071724

Article  PubMed  Google Scholar 

D’Souza N, Hicks G, Beable R et al (2021) Magnetic resonance imaging (MRI) for diagnosis of acute appendicitis. Cochrane Database Syst Rev. https://doi.org/10.1002/14651858.CD012028.pub2

Article  PubMed  PubMed Central  Google Scholar 

Krishnan N, Anand S, Pakkasjärvi N et al (2022) Mean platelet volume in the diagnosis of acute appendicitis in the pediatric population: a systematic review and meta-analysis. Diagnostics (Basel) 12:1596. https://doi.org/10.3390/diagnostics12071596

Article  PubMed  Google Scholar 

Anand S, Pakkasjärvi N, Bajpai M et al (2022) Utility of pentraxin-3 as a biomarker for diagnosis of acute appendicitis: a systematic review and meta-analysis. Pediatr Surg Int 38:1105–1112. https://doi.org/10.1007/s00383-022-05149-4

Article  PubMed  PubMed Central  Google Scholar 

Anand S, Krishnan N, Jukić M et al (2022) Utility of red cell distribution width (RDW) as a noninvasive biomarker for the diagnosis of acute appendicitis: a systematic review and meta-analysis of 5222 cases. Diagnostics (Basel) 12:1011. https://doi.org/10.3390/diagnostics12041011

Article  PubMed  Google Scholar 

Ulrich K, Jakob U (2019) The role of thiols in antioxidant systems. Free Radic Biol Med 140:14–27. https://doi.org/10.1016/j.freeradbiomed.2019.05.035

Article  CAS  PubMed  PubMed Central  Google Scholar 

Herrmann JM, Becker K, Dick TP (2015) Highlight: dynamics of thiol-based redox switches. Biol Chem 396:385–387. https://doi.org/10.1515/hsz-2015-0135

Article  CAS  PubMed  Google Scholar 

Leichert LI, Dick TP (2015) Incidence and physiological relevance of protein thiol switches. Biol Chem 396:389–399. https://doi.org/10.1515/hsz-2014-0314

Article  CAS  PubMed  Google Scholar 

Groitl B, Jakob U (2014) Thiol-based redox switches. Biochim Biophys Acta 1844:1335–1343. https://doi.org/10.1016/j.bbapap.2014.03.007

Article  CAS  PubMed  PubMed Central  Google Scholar 

Erel Ö, Erdoğan S (2020) Thiol-disulfide homeostasis: an integrated approach with biochemical and clinical aspects. Turk J Med Sci 50:1728–1738. https://doi.org/10.3906/sag-2003-64

Article  CAS  PubMed  PubMed Central  Google Scholar 

Elmas B, Yildiz T, Yazar H et al (2020) New oxidative stress markers useful in the diagnosis of acute appendicitis in children: thiol/disulfide homeostasis and the asymmetric dimethylarginine Level. Pediatr Emerg Care 36:362–367. https://doi.org/10.1097/PEC.0000000000001339

Article  PubMed  Google Scholar 

Şahin C, Güler EM, KaramanAyyıldız HN et al (2023) The role of IL-6, thiol-disulfide homeostasis, and inflammatory biomarkers in the prediction of acute appendicitis in children: a controlled study. Pediatr Surg Int 39:75. https://doi.org/10.1007/s00383-023-05366-5

Article  PubMed  Google Scholar 

crd.york.ac.uk/prospero/display_record.php?RecordID=407003

Ottawa Hospital Research Institute. https://www.ohri.ca/programs/clinical_epidemiology/oxford.asp Accessed 6 Mar 2024

Ayengin K, Alp HH, Avci V, Huyut Z (2021) The effect of laparoscopic and open surgery on oxidative DNA damage and IL-37 in children with acute appendicitis. Ir J Med Sci 190:281–289. https://doi.org/10.1007/s11845-020-02317-0

Article  CAS  PubMed  Google Scholar 

Ozyazici S, Karateke F, Turan U et al (2016) A novel oxidative stress mediator in acute appendicitis: thiol/disulphide homeostasis. Mediators Inflamm 2016:6761050. https://doi.org/10.1155/2016/6761050

Article  CAS  PubMed  PubMed Central  Google Scholar 

Tanrıverdi F, Yıldırım Ç, Şener A, Erel Ö (2022) Are thiol-disulfide homeostasis & neutrophil-to-lymphocyte ratio useful in the differential diagnosis of acute familial Mediterranean fever attacks & acute appendicitis? Indian J Med Res 155:280–285. https://doi.org/10.4103/ijmr.IJMR_1610_19

Article  PubMed  PubMed Central  Google Scholar 

Demi̇r S, Günal YD, Özmen İ et al (2020) Can thiol disulphide homeostasis help in the differential diagnosis of appendicitis in children? Turkish J Pediatric Dis 14:236–243. https://doi.org/10.12956/tchd.627936

Article  Google Scholar 

Ünsal A, Yavuz A, Buluş H et al (2022) Comparison of thiol-disulfide hemostasis with inflammatory markers in the inflammatory process of acute appendicitis. Cureus 14:e28891. https://doi.org/10.7759/cureus.28891

Article  PubMed  PubMed Central  Google Scholar 

Gökhan S, Aydın İE, PamukçuGünaydın G et al (2020) Comparison of thiol/disulphide homeostasis with modified alvarado and RIPASA scores in the diagnosis of acute appendicitis. Turkish J Trauma Emerg Surg 26:389–395. https://doi.org/10.14744/tjtes.2019.65118

Article  Google Scholar 

Dumlu EG, Tokaç M, Bozkurt B et al (2014) Correlation between the serum and tissue levels of oxidative stress markers and the extent of inflammation in acute appendicitis. Clinics (Sao Paulo) 69:677–682. https://doi.org/10.6061/clinics/2014(10)05

Article  PubMed  Google Scholar 

Yilmaz FM, Yilmaz G, Erol MF et al (2010) Nitric oxide, lipid peroxidation and total thiol levels in acute appendicitis. J Clin Lab Anal 24:63–66. https://doi.org/10.1002/jcla.20301

Article  CAS  PubMed  PubMed Central  Google Scholar 

Ozer OF, Guler EM, Kocyigit A et al (2018) Raftlin, presepsin levels and thiol-disulphide homeostasis in acute appendicitis: a pilot study. J Pak Med Assoc 68:1660–1665

PubMed  Google Scholar 

Uğur C, Madenci H, Kurku H, Neşelioğlu S (2020) The use of thiol/disulfide homeostasis parameters in the diagnosis of acute appendicitis in children. J Pediatr Infect Dis 15:195–199. https://doi.org/10.1055/s-0040-1709700

Article  Google Scholar 

Yildiz H (2020) Thiol/disulphide homeostasis in intensive care unit patients with sepsis and septic shock. Turk J Med Sci 50:811–816. https://doi.org/10.3906/sag-1905-148

Article  CAS  PubMed  PubMed Central  Google Scholar 

Ayar G, Sahin S, Men Atmaca Y et al (2019) Thiol-disulphide homeostasis is an oxidative stress indicator in critically ill children with sepsis. Arch Argent Pediatr 117:143–148. https://doi.org/10.5546/aap.2019.eng.143

Article  PubMed  Google Scholar 

Acharya A, Markar SR, Ni M, Hanna GB (2017) Biomarkers of acute appendicitis: systematic review and cost-benefit trade-off analysis. Surg Endosc 31:1022–1031. https://doi.org/10.1007/s00464-016-5109-1

Article  PubMed  Google Scholar