We are grateful to Dr. Mina Takeichi, Shingo Nakao, Kenji Maehara, Yuka Iwaya, Shinya Suematsu, Yasuhiro Okabe, Kandai Nozu, and Satoshi Hisano for their assistance with this study. We appreciate the help of Dr. Brian Quinn (Japan Medical Communication, Fukuoka, Japan) in editing the manuscript. The authors declare no conflict of interest associated with this study.