Noone DG, Iijima K, Parekh R (2018) Idiopathic nephrotic syndrome in children. Lancet 392:61–74. https://doi.org/10.1016/S0140-6736(18)30536-1

Article  PubMed  Google Scholar 

Veltkamp F, Rensma LR, Bouts AHM, LEARNS consortium (2021) Incidence and relapse of idiopathic nephrotic syndrome: Meta-analysis. Pediatrics 148:e2020029249. https://doi.org/10.1542/peds.2020-029249

Article  PubMed  Google Scholar 

Banh THM, Hussain-Shamsy N, Patel V et al (2016) Ethnic differences in incidence and outcomes of childhood nephrotic syndrome. Clin J Am Soc Nephrol 11:1760–1768. https://doi.org/10.2215/CJN.00380116

Article  CAS  PubMed  PubMed Central  Google Scholar 

Carter SA, Mistry S, Fitzpatrick J et al (2020) Prediction of short- and long-term outcomes in childhood nephrotic syndrome. Kidney Int Rep 5:426–434. https://doi.org/10.1016/j.ekir.2019.12.015

Article  PubMed  Google Scholar 

Khullar S, Banh T, Vasilevska-Ristovska J et al (2021) Impact of steroids and steroid-sparing agents on quality of life in children with nephrotic syndrome. Pediatr Nephrol 36:93–102. https://doi.org/10.1007/s00467-020-04684-3

Article  PubMed  Google Scholar 

(1981) Primary nephrotic syndrome in children: clinical significance of histopathologic variants of minimal change and of diffuse mesangial hypercellularity. A report of the international study of kidney disease in children. Kidney Int 20:765–771. https://doi.org/10.1038/ki.1981.209

Mushtaq T (2002) The impact of corticosteroids on growth and bone health. Arch Dis Child 87:93–96. https://doi.org/10.1136/adc.87.2.93

Article  CAS  PubMed  PubMed Central  Google Scholar 

John K, Marino JS, Sanchez ER, Hinds TD (2016) The glucocorticoid receptor: cause of or cure for obesity? Am J Physiol Endocrinol Metab 310:E249–E257. https://doi.org/10.1152/ajpendo.00478.2015

Article  PubMed  Google Scholar 

Foster BJ, Shults J, Zemel BS, Leonard MB (2006) Risk factors for glucocorticoid-induced obesity in children with steroid-sensitive nephrotic syndrome. Pediatr Nephrol 21:973–980. https://doi.org/10.1007/s00467-006-0100-z

Article  PubMed  Google Scholar 

Lee JM, Kronbichler A, Shin JI, Oh J (2020) Review on long-term non-renal complications of childhood nephrotic syndrome. Acta Paediatr 109:460–470. https://doi.org/10.1111/apa.15035

Article  PubMed  Google Scholar 

Göknar N, Webb H, Waters A, Tullus K (2022) Long-term obesity prevalence and linear growth in children with idiopathic nephrotic syndrome: is normal growth and weight control possible with steroid-sparing drugs and low-dose steroids for relapses? Pediatr Nephrol 37:1575–1584. https://doi.org/10.1007/s00467-021-05288-1

Article  PubMed  Google Scholar 

Rovin BH, Adler SG, Barratt J et al (2021) KDIGO 2021 clinical practice guideline for the management of glomerular diseases. Kidney Int 100:S1–S276. https://doi.org/10.1016/j.kint.2021.05.021

Article  Google Scholar 

de Onis M (2007) Development of a WHO growth reference for school-aged children and adolescents. Bull World Health Organ 85:660–667. https://doi.org/10.2471/BLT.07.043497

Article  PubMed  PubMed Central  Google Scholar 

WHO Multicentre Growth Reference Study Group (2006) WHO child growth standards based on length/height, weight and age. Acta Paediatr Suppl 450:76–85. https://doi.org/10.1111/j.1651-2227.2006.tb02378.x

Article  Google Scholar 

Dong Y, Peng C-YJ (2013) Principled missing data methods for researchers. Springerplus 2:222. https://doi.org/10.1186/2193-1801-2-222

Article  PubMed  PubMed Central  Google Scholar 

van Buuren S, Groothuis-Oudshoorn K (2011) mice: Multivariate Imputation by Chained Equations in R. J Stat Soft 45:1–67. https://doi.org/10.18637/jss.v045.i03

Article  Google Scholar 

Soliman AT, Hamed N, De Sanctis V et al (2022) The long-term (five years) effects of prednisone therapy in children with frequently relapsing nephrotic syndrome: A controlled study of anthropometric parameters and metabolic abnormalities. Acta Biomed 93:e2022303. https://doi.org/10.23750/abm.v93i5.13459

Article  CAS  PubMed  PubMed Central  Google Scholar 

Ishikura K, Yoshikawa N, Nakazato H et al (2015) Morbidity in children with frequently relapsing nephrosis: 10-year follow-up of a randomized controlled trial. Pediatr Nephrol 30:459–468. https://doi.org/10.1007/s00467-014-2955-8

Article  PubMed  Google Scholar 

Rüth E-M, Kemper MJ, Leumann EP et al (2005) Children with steroid-sensitive nephrotic syndrome come of age: long-term outcome. J Pediatr 147:202–207. https://doi.org/10.1016/j.jpeds.2005.03.050

Article  PubMed  Google Scholar 

Skrzypczyk P, Panczyk-Tomaszewska M, Roszkowska-Blaim M et al (2014) Long-term outcomes in idiopathic nephrotic syndrome: from childhood to adulthood. Clin Nephrol 81:166–173. https://doi.org/10.5414/CN108044

Article  PubMed  Google Scholar 

Statistics Canada (2020) Overweight and obesity based on measured body mass index, by age group and sex. https://doi.org/10.25318/1310037301-eng

Emma F, Sesto A, Rizzoni G (2003) Long-term linear growth of children with severe steroid-responsive nephrotic syndrome. Pediatr Nephrol 18:783–788. https://doi.org/10.1007/s00467-003-1176-3

Article  PubMed  Google Scholar 

Donatti TL, Koch VH, Fujimura MD, Okay Y (2003) Growth in steroid-responsive nephrotic syndrome: a study of 85 pediatric patients. Pediatr Nephrol 18:789–795. https://doi.org/10.1007/s00467-003-1142-0

Article  PubMed  Google Scholar 

Motoyama O, Iitaka K (2007) Final height in children with steroid-sensitive nephrotic syndrome. Pediatr Int 49:623–625. https://doi.org/10.1111/j.1442-200X.2007.02429.x

Article  PubMed  Google Scholar 

Aydin M, Franke I, Kurylowicz L et al (2019) The long-term outcome of childhood nephrotic syndrome in Germany: a cross-sectional study. Clin Exp Nephrol 23:676–688. https://doi.org/10.1007/s10157-019-01696-8

Article  PubMed  Google Scholar 

Fakhouri F, Bocquet N, Taupin P et al (2003) Steroid-sensitive nephrotic syndrome: from childhood to adulthood. Am J Kidney Dis 41:550–557. https://doi.org/10.1053/ajkd.2003.50116

Article  PubMed  Google Scholar 

Donatti TL, Koch VH (2009) Final height of adults with childhood-onset steroid-responsive idiopathic nephrotic syndrome. Pediatr Nephrol 24:2401–2408. https://doi.org/10.1007/s00467-009-1301-z

Article  PubMed  Google Scholar 

Simmonds J, Grundy N, Trompeter R, Tullus K (2010) Long-term steroid treatment and growth: a study in steroid dependent nephrotic syndrome. Arch Dis Child 95:146–149. https://doi.org/10.1136/adc.2007.129957

Article  PubMed  Google Scholar 

Constantinescu A, Maruntelu S, Velis E et al (2019) Strategies to minimize growth retardation in children with steroid-sensitive nephrotic syndrome. J Clin Exp Nephrol 4:06

Google Scholar 

Ribeiro D, Zawadynski S, Pittet LF et al (2015) Effect of glucocorticoids on growth and bone mineral density in children with nephrotic syndrome. Eur J Pediatr 174:911–917. https://doi.org/10.1007/s00431-014-2479-z

Article  CAS  PubMed  Google Scholar 

Kyrieleis HAC, Löwik MM, Pronk I et al (2009) Long-term outcome of biopsy-proven, frequently relapsing minimal-change nephrotic syndrome in children. Clin J Am Soc Nephrol 4:1593–1600. https://doi.org/10.2215/CJN.05691108

Article  PubMed  PubMed Central  Google Scholar 

Topaloğlu R, Gülhan B, Çelegen K et al (2019) Rituximab for children with difficult-to-treat nephrotic syndrome: Its effects on disease progression and growth. Front Pediatr 7:313. https://doi.org/10.3389/fped.2019.00313

Article  PubMed  PubMed Central  Google Scholar 

Sinha A, Bhatia D, Gulati A et al (2015) Efficacy and safety of rituximab in children with difficult-to-treat nephrotic syndrome. Nephrol Dial Transplant 30:96–106. https://doi.org/10.1093/ndt/gfu267

Article  CAS