Unconventional T Cells Influence Clinical Outcome After Allogeneic Hematopoietic Cell Transplantation

Andrlova H, van den Brink MRM, Markey KA. An unconventional view of T cell reconstitution after allogeneic hematopoietic cell transplantation. Front Oncol. 2020;10:608923. https://doi.org/10.3389/fonc.2020.608923.

Article  PubMed  Google Scholar 

Mori L, Lepore M, De Libero G. The immunology of CD1- and MR1-restricted T cells. Annu Rev Immunol. 2016;34:479–510. https://doi.org/10.1146/annurev-immunol-032414-112008.

Article  CAS  PubMed  Google Scholar 

Treiner E, Duban L, Bahram S, Radosavljevic M, Wanner V, Tilloy F, Affaticati P, Gilfillan S, Lantz O. Selection of evolutionarily conserved mucosal-associated invariant T cells by MR1. Nature. 2003;422(6928):164–9. https://doi.org/10.1038/nature01433.

Article  CAS  PubMed  Google Scholar 

Rudak PT, Choi J, Haeryfar SMM. MAIT cell-mediated cytotoxicity: Roles in host defense and therapeutic potentials in infectious diseases and cancer. J Leukoc Biol. 2018;104(3):473–86. https://doi.org/10.1002/JLB.4RI0118-023R.

Article  CAS  PubMed  Google Scholar 

Sandstrom A, Peigne CM, Leger A, Crooks JE, Konczak F, Gesnel MC, Breathnach R, Bonneville M, Scotet E, Adams EJ. The intracellular B30.2 domain of butyrophilin 3A1 binds phosphoantigens to mediate activation of human Vgamma9Vdelta2 T cells. Immunity. 2014;40(4):490–500. https://doi.org/10.1016/j.immuni.2014.03.003.

Article  CAS  PubMed  PubMed Central  Google Scholar 

Gao MG, Hong Y, Zhao XY, Pan XA, Sun YQ, Kong J, Wang ZD, Wang FR, Wang JZ, Yan CH, Wang Y, Huang XJ, Zhao XS. The potential roles of mucosa-associated invariant T cells in the pathogenesis of gut graft-versus-host disease after hematopoietic stem cell transplantation. Front Immunol. 2021;12:720354. https://doi.org/10.3389/fimmu.2021.720354.

Article  CAS  PubMed  PubMed Central  Google Scholar 

Bhattacharyya A, Hanafi LA, Sheih A, Golob JL, Srinivasan S, Boeckh MJ, Pergam SA, Mahmood S, Baker KK, Gooley TA, Milano F, Fredricks DN, Riddell SR, Turtle CJ. Graft-derived reconstitution of mucosal-associated invariant T cells after allogeneic hematopoietic cell transplantation. Biol Blood Marrow Transplant. 2018;24(2):242–51. https://doi.org/10.1016/j.bbmt.2017.10.003.

Article  CAS  PubMed  Google Scholar 

Ravens S, Schultze-Florey C, Raha S, Sandrock I, Drenker M, Oberdorfer L, Reinhardt A, Ravens I, Beck M, Geffers R, von Kaisenberg C, Heuser M, Thol F, Ganser A, Forster R, Koenecke C, Prinz I. Human gammadelta T cells are quickly reconstituted after stem-cell transplantation and show adaptive clonal expansion in response to viral infection. Nat Immunol. 2017;18(4):393–401. https://doi.org/10.1038/ni.3686.

Article  CAS  PubMed  Google Scholar 

Stocker N, Gaugler B, Labopin M, Farge A, Ye Y, Ricard L, Brissot E, Dulery R, Sestili S, Battipaglia G, Mediavilla C, Paviglianiti A, Banet A, Van De Wyngaert Z, Ledraa T, Mohty M, Malard F. High-dose post-transplant cyclophosphamide impairs gammadelta T-cell reconstitution after haploidentical haematopoietic stem cell transplantation using low-dose antithymocyte globulin and peripheral blood stem cell graft. Clin Transl Immunology. 2020;9(9):e1171. https://doi.org/10.1002/cti2.1171.

Article  CAS  PubMed  PubMed Central  Google Scholar 

Minculescu L, Marquart HV, Ryder LP, Andersen NS, Schjoedt I, Friis LS, Kornblit BT, Petersen SL, Haastrup E, Fischer-Nielsen A, Reekie J, Sengelov H. Improved overall survival, relapse-free-survival, and less graft-vs.-host-disease in patients with high immune reconstitution of TCR gamma delta cells 2 months after allogeneic stem cell transplantation. Front Immunol. 2019;10:1997. https://doi.org/10.3389/fimmu.2019.01997.

Article  CAS  PubMed  PubMed Central  Google Scholar 

Wragg KM, Tan HX, Kristensen AB, Nguyen-Robertson CV, Kelleher AD, Parsons MS, Wheatley AK, Berzins SP, Pellicci DG, Kent SJ, Juno JA. High CD26 and low CD94 expression identifies an IL-23 responsive Vdelta2(+) T cell subset with a MAIT cell-like transcriptional profile. Cell Rep. 2020;31(11):107773. https://doi.org/10.1016/j.celrep.2020.107773.

Article  CAS  PubMed  Google Scholar 

Varelias A, Bunting MD, Ormerod KL, Koyama M, Olver SD, Straube J, Kuns RD, Robb RJ, Henden AS, Cooper L, Lachner N, Gartlan KH, Lantz O, Kjer-Nielsen L, Mak JY, Fairlie DP, Clouston AD, McCluskey J, Rossjohn J, Lane SW, Hugenholtz P, Hill GR. Recipient mucosal-associated invariant T cells control GVHD within the colon. J Clin Invest. 2018;128(5):1919–36. https://doi.org/10.1172/JCI91646.

Article  PubMed  PubMed Central  Google Scholar 

Solders M, Erkers T, Gorchs L, Poiret T, Remberger M, Magalhaes I, Kaipe H. Mucosal-associated Invariant T cells display a poor reconstitution and altered phenotype after allogeneic hematopoietic stem cell transplantation. Front Immunol. 2017;8:1861. https://doi.org/10.3389/fimmu.2017.01861.

Article  CAS  PubMed  PubMed Central  Google Scholar 

Kawaguchi K, Umeda K, Hiejima E, Iwai A, Mikami M, Nodomi S, Saida S, Kato I, Hiramatsu H, Yasumi T, Nishikomori R, Kondo T, Takaori-Kondo A, Heike T, Adachi S. Influence of post-transplant mucosal-associated invariant T cell recovery on the development of acute graft-versus-host disease in allogeneic bone marrow transplantation. Int J Hematol. 2018;108(1):66–75. https://doi.org/10.1007/s12185-018-2442-2.

Article  PubMed  Google Scholar 

Konuma T, Kohara C, Watanabe E, Takahashi S, Ozawa G, Suzuki K, Mizukami M, Nagai E, Jimbo K, Kaito Y, Isobe M, Kato S, Takahashi S, Chiba A, Miyake S, Tojo A. Reconstitution of circulating mucosal-associated invariant T cells after allogeneic hematopoietic cell transplantation: its association with the riboflavin synthetic pathway of gut microbiota in cord blood transplant recipients. J Immunol. 2020;204(6):1462–73. https://doi.org/10.4049/jimmunol.1900681.

Article  CAS  PubMed  Google Scholar 

Hinks TSC, Marchi E, Jabeen M, Olshansky M, Kurioka A, Pediongco TJ, Meehan BS, Kostenko L, Turner SJ, Corbett AJ, Chen Z, Klenerman P, McCluskey J. Activation and in vivo evolution of the MAIT cell transcriptome in mice and humans reveals tissue repair functionality. Cell Rep. 2019;28(12):3249-3262e5. https://doi.org/10.1016/j.celrep.2019.07.039.

Article  CAS  PubMed  PubMed Central  Google Scholar 

Ruggeri A, Labopin M, Ciceri F, Mohty M, Nagler A. Definition of GvHD-free, relapse-free survival for registry-based studies: an ALWP-EBMT analysis on patients with AML in remission. Bone Marrow Transplant. 2016;51(4):610–1. https://doi.org/10.1038/bmt.2015.305.

Article  CAS  PubMed  Google Scholar 

留言 (0)

沒有登入
gif