We acknowledge patients and their families and the nurse staff of our Pediatric Oncology/Hematology division for their valuable support.

Florence STAT3 GOF consortium: Linda Zollo3, Daniela Cuzzubbo2, Stefano Frenos2, Laura Lacitignola6, Maria Chiara Sanvito2, Veronica Tintori2, Paolo Lionetti5,6(ORCID: 0000-0001-8029-3904),

2Centre of Excellence, Division of Pediatric Oncology/Hematology, Meyer Children’s Hospital IRCCS, Florence, Italy

3Department of Health Sciences, University of Florence, Florence, Italy

5Department of Neurosciences, Psychology, Drug Research and Child Health (NEUROFARBA), University of Florence, Florence, Italy

6Gastroenterology and Nutrition Unit, Meyer Children’s Hospital IRCCS, Florence, Italy.