Photobiomodulation in experimental models of Alzheimer’s disease: state-of-the-art and translational perspectives

Scheltens P, De Strooper B, Kivipelto M, Holstege H, Chetelat G, Teunissen CE, et al. Alzheimer’s disease. Lancet. 2021;397:1577–90.

Article  CAS  PubMed  PubMed Central  Google Scholar 

Gillis C, Montenigro P, Nejati M, Maserejian N. Estimating prevalence of early Alzheimer’s disease in the United States, accounting for racial and ethnic diversity. Alzheimers Dement. 2023;19:1841–8.

Article  PubMed  Google Scholar 

Lane CA, Hardy J, Schott JM. Alzheimer’s disease. Eur J Neurol. 2018;25:59–70.

Article  CAS  PubMed  Google Scholar 

2023 Alzheimer’s disease facts and figures. Alzheimers Dement. 2023;19:1598–695.

Zhang Y, Chen H, Li R, Sterling K, Song W. Amyloid beta-based therapy for Alzheimer’s disease: challenges, successes and future. Signal Transduct Target Ther. 2023;8:248.

Article  CAS  PubMed  PubMed Central  Google Scholar 

Huang Z, Jordan JD, Zhang Q. Myelin pathology in Alzheimer’s disease: potential therapeutic opportunities. Aging Dis. 2023;15(2):698–713.

Article  Google Scholar 

Cummings J, Osse AML, Cammann D, Powell J, Chen J. Anti-amyloid monoclonal antibodies for the treatment of Alzheimer’s disease. BioDrugs. 2024;38:5–22.

Article  CAS  PubMed  Google Scholar 

Cummings J, Zhou Y, Lee G, Zhong K, Fonseca J, Cheng F. Alzheimer’s disease drug development pipeline: 2023. Alzheimers Dement (N Y). 2023;9:e12385.

Article  PubMed  Google Scholar 

Ibrahim MM, Gabr MT. Multitarget therapeutic strategies for Alzheimer’s disease. Neural Regen Res. 2019;14:437–40.

Article  CAS  PubMed  PubMed Central  Google Scholar 

Albertini C, Salerno A, de SenaMurteira Pinheiro P, Bolognesi ML. From combinations to multitarget-directed ligands: A continuum in Alzheimer’s disease polypharmacology. Med Res Rev. 2021;41:2606–33.

Article  PubMed  Google Scholar 

Chung H, Dai T, Sharma SK, Huang YY, Carroll JD, Hamblin MR. The nuts and bolts of low-level laser (light) therapy. Ann Biomed Eng. 2012;40:516–33.

Article  PubMed  Google Scholar 

Salehpour F, Mahmoudi J, Kamari F, Sadigh-Eteghad S, Rasta SH, Hamblin MR. Brain photobiomodulation therapy: a narrative review. Mol Neurobiol. 2018;55:6601–36.

Article  CAS  PubMed  PubMed Central  Google Scholar 

Hamblin MR, Salehpour F. Photobiomodulation of the brain: shining light on Alzheimer’s and other neuropathological diseases. J Alzheimers Dis. 2021;83:1395–7.

Article  CAS  PubMed  Google Scholar 

Cardoso FDS, Gonzalez-Lima F, Gomes da Silva S. Photobiomodulation for the aging brain. Ageing Res Rev. 2021;70:101415.

Article  CAS  PubMed  Google Scholar 

Enengl J, Hamblin MR, Dungel P. Photobiomodulation for Alzheimer’s disease: translating basic research to clinical application. J Alzheimers Dis. 2020;75:1073–82.

Article  PubMed  PubMed Central  Google Scholar 

Hamblin MR. Shining light on the head: Photobiomodulation for brain disorders. BBA Clin. 2016;6:113–24.

Article  PubMed  PubMed Central  Google Scholar 

Yang L, Wu C, Parker E, Li Y, Dong Y, Tucker L, et al. Non-invasive photobiomodulation treatment in an Alzheimer disease-like transgenic rat model. Theranostics. 2022;12:2205–31.

Article  CAS  PubMed  PubMed Central  Google Scholar 

Blivet G, Relano-Gines A, Wachtel M, Touchon J. A randomized, double-blind, and sham-controlled trial of an innovative brain-gut photobiomodulation therapy: safety and patient compliance. J Alzheimers Dis. 2022;90:811–22.

Article  CAS  PubMed  Google Scholar 

Baik JS, Lee TY, Kim NG, Pak K, Ko SH, Min JH, et al. Effects of photobiomodulation on changes in cognitive function and regional cerebral blood flow in patients with mild cognitive impairment: a pilot uncontrolled trial. J Alzheimers Dis. 2021;83:1513–9.

Article  CAS  PubMed  Google Scholar 

Saltmarche AE, Naeser MA, Ho KF, Hamblin MR, Lim L. Significant improvement in cognition in mild to moderately severe dementia cases treated with transcranial plus intranasal photobiomodulation: case series report. Photomed Laser Surg. 2017;35:432–41.

Article  PubMed  PubMed Central  Google Scholar 

Gordon LC, Johnstone DM. Remote photobiomodulation: an emerging strategy for neuroprotection. Neural Regen Res. 2019;14:2086–7.

Article  PubMed  PubMed Central  Google Scholar 

Hamblin MR. Photobiomodulation for Alzheimer’s disease: has the light dawned? Photonics. 2019;6(3):77.

Article  CAS  PubMed  PubMed Central  Google Scholar 

Monteiro F, Carvalho O, Sousa N, Silva FS, Sotiropoulos I. Photobiomodulation and visual stimulation against cognitive decline and Alzheimer’s disease pathology: a systematic review. Alzheimers Dement (N Y). 2022;8:e12249.

Article  PubMed  Google Scholar 

Lee TL, Ding Z, Chan AS. Can transcranial photobiomodulation improve cognitive function? A systematic review of human studies. Ageing Res Rev. 2023;83:101786.

Article  PubMed  Google Scholar 

Tao L, Liu Q, Zhang F, Fu Y, Zhu X, Weng X, et al. Microglia modulation with 1070-nm light attenuates Abeta burden and cognitive impairment in Alzheimer’s disease mouse model. Light Sci Appl. 2021;10:179.

Article  CAS  PubMed  PubMed Central  Google Scholar 

Wang M, Cao J, Amakye WK, Gong C, Li Q, Ren J. Mid infrared light treatment attenuates cognitive decline and alters the gut microbiota community in APP/PS1 mouse model. Biochem Biophys Res Commun. 2020;523:60–5.

Article  CAS  PubMed  Google Scholar 

Bowen R, Arany PR. Use of either transcranial or whole-body photobiomodulation treatments improves COVID-19 brain fog. J Biophotonics. 2023;16:e202200391.

Article  PubMed  Google Scholar 

Fitzmaurice B, Heneghan NR, Rayen A, Soundy A. Whole-body photobiomodulation therapy for chronic pain: a protocol for a feasibility trial. BMJ Open. 2022;12:e060058.

Article  PubMed  PubMed Central  Google Scholar 

Gordon LC, Martin KL, Torres N, Benabid AL, Mitrofanis J, Stone J, et al. Remote photobiomodulation targeted at the abdomen or legs provides effective neuroprotection against parkinsonian MPTP insult. Eur J Neurosci. 2023;57:1611–24.

Article  CAS  PubMed  PubMed Central  Google Scholar 

Kim B, Brandli A, Mitrofanis J, Stone J, Purushothuman S, Johnstone DM. Remote tissue conditioning - an emerging approach for inducing body-wide protection against diseases of ageing. Ageing Res Rev. 2017;37:69–78.

Article  PubMed  Google Scholar 

Blivet G, Meunier J, Roman FJ, Touchon J. Neuroprotective effect of a new photobiomodulation technique against Abeta(25–35) peptide-induced toxicity in mice: Novel hypothesis for therapeutic approach of Alzheimer’s disease suggested. Alzheimers Dement (N Y). 2018;4:54–63.

Article  PubMed  Google Scholar 

Chen Q, Wu J, Dong X, Yin H, Shi X, Su S, et al. Gut flora-targeted photobiomodulation therapy improves senile dementia in an Ass-induced Alzheimer’s disease animal model. J Photochem Photobiol B. 2021;216:112152.

Article  CAS  PubMed  Google Scholar 

Wu X, Shen Q, Chang H, Li J, Xing D. Promoted CD4(+) T cell-derived IFN-gamma/IL-10 by photobiomodulation therapy modulates neurogenesis to ameliorate cognitive deficits in APP/PS1 and 3xTg-AD mice. J Neuroinflammation. 2022;19:253.

Article  CAS  PubMed  PubMed Central  Google Scholar 

Karu TI, Pyatibrat LV, Kalendo GS. Photobiological modulation of cell attachment via cytochrome c oxidase. Photochem Photobiol Sci. 2004;3:211–6.

Article  CAS  PubMed  Google Scholar 

AhamedBasha A, Mathangi DC, Shyamala R. Effect of LED photobiomodulation on fluorescent light induced changes in cellular ATPases and Cytochrome c oxidase activity in Wistar rat. Lasers Med Sci. 2016;31:1803–9.

Article  Google Scholar 

Wikstrom M, Krab K, Sharma V. Oxygen activation and energy conservation by cytochrome c oxidase. Chem Rev. 2018;118:2469–90.

Article  CAS  PubMed  PubMed Central  Google Scholar 

Cooper CE, Cope M, Springett R, Amess PN, Penrice J, Tyszczuk L, et al. Use of mitochondrial inhibitors to demonstrate that cytochrome oxidase near-infrared spectroscopy can measure mitochondrial dysfunction noninvasively in the brain. J Cereb Blood Flow Metab. 1999;19:27–38.

Article  CAS  PubMed  Google Scholar 

de Freitas LF, Hamblin MR. Proposed mechanisms of photobiomodulation or low-level light therapy. IEEE J Sel Top Quantum Electron. 2016;22(3):7000417.

Article 

留言 (0)

沒有登入
gif