Salt sensitivity risk derived from nocturnal dipping and 24-h heart rate predicts long-term blood pressure reduction following renal denervation

aHuman Neurotransmitter and Neurovascular Hypertension & Kidney Diseases Laboratories, Baker Heart and Diabetes Institute, Melbourne

bDobney Hypertension Centre, Medical School – Royal Perth Hospital Unit and RPH Research Foundation, The University of Western Australia, Perth, Western Australia

cHuman Autonomic Neurophysiology Laboratory, Baker Heart and Diabetes Institute

dIverson Health Innovation Research Institute and School of Health Sciences, Swinburne University of Technology, Melbourne

eDepartment of Cardiology, Alfred Health, Melbourne, Victoria

fDepartments of Cardiology and Nephrology, Royal Perth Hospital, Perth, Western Australia, Australia

Correspondence to Markus P. Schlaich, Dobney Chair in Clinical Research, Medical School – Royal Perth Hospital Unit, The University of Western Australia, Level 3, MRF Building, Rear 50 Murray St, Perth, WA 6000, Australia. Tel: +61 8 9224 0334; fax: +61 8 9224 0374; e-mail: [email protected]

Abbreviations: ABPM, ambulatory blood pressure monitoring; RDN, renal denervation; SSI, salt sensitivity index

Received 11 October, 2023

Revised 8 December, 2023

Accepted 14 December, 2023

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