Targeted transcriptional upregulation of SENP1 by CRISPR activation enhances deSUMOylation pathways to elicit antinociception in the spinal nerve ligation model of neuropathic pain

aDepartment of Molecular Pathobiology, College of Dentistry, New York University, New York, NY, United States

bNYU Pain Research Center, New York, NY, United States

cSchool of Medicine, Department of Pharmacology and Physiology, Saint Louis University, Saint Louis, MO, United States

dDepartment of Neuroscience and Physiology and Neuroscience Institute, School of Medicine, New York University, New York, NY, United States

*Corresponding author. Address: Department of Molecular Pathobiology, College of Dentistry, New York University, 433 First Ave, 8th floor, New York, NY 10010, United States. Tel.: (520) 271-0433. E-mail address: [email protected] (R. Khanna).

Sponsorships or competing interests that may be relevant to content are disclosed at the end of this article.

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