Iqbal K., Grundke-Iqbal I., Zaidi T., Merz P.A., Wen G.Y., Shaikh S.S., Wisniewski H.M., Alafuzoff I., Winblad B. 1986. Defective brain microtubule assembly in Alzheimer’s disease. Lancet. 2 (8504), 421‒426.
Article CAS PubMed Google Scholar
Sherrington R., Rogaev E.I., Liang Y., Rogaeva E.A., Levesque G., Ikeda M., Chi H., Lin C., Li G., Holman K., Tsuda T., Mar L., Foncin J.F., Bruni A.C., Montesi M.P., Sorbi S., Rainero I., Pinessi L., Nee L., Chumakov I., Pollen D., Brookes A., Sanseau P., Polinsky R.J., Wasco W., Da Silva H.A., Haines J.L., Perkicak-Vance M.A., Tanzi R.E., Roses A.D., Fraser P.E., Rommens J.M., St George-Hyslop P.H. 1995. Cloning of a gene bearing missense mutations in early-onset familial Alzheimer’s disease. Nature. 375 (6534), 754‒760.
Article CAS PubMed Google Scholar
Bagyinszky E., Youn Y.C., An S.S.A., Kim S. 2016. Mutations, associated with early-onset Alzheimer’s disease, discovered in Asian countries. Clin. Int. Aging. 11, 1467‒1488.
Unger M.S., Schernthaner P., Marschallinger J., Mrowetz H., Aigner L. 2018. Microglia prevent peripheral immune cell invasion and promote an anti-inflammatory environment in the brain of APP-PS1 transgenic mice. J. Neuroinflammation. 15 (1), 274.
Article CAS PubMed PubMed Central Google Scholar
Weiner M.W., Veitch D.P., Aisen P.S., Beckett L.A., Cairns N.J., Cedarbaum J., Green R.C., Harvey D., Jack C.R., Jagust W., Luthman J., Morris J.C., Petersen R.C., Saykin A.J., Shaw L., Shen L., Schwarz A., Toga A.W., Trojanowski J.Q., Alzheimer’s Disease Neuroimaging I. 2015. 2014 Update of the Alzheimer’s Disease Neuroimaging Initiative: A review of papers published since its inception. Alzheimers Demen. 11 (6), e1‒e120.
Widelitz R. 2005. Wnt signaling through canonical and non-canonical pathways: recent progress. Growth Factors. 23 (2), 111‒116.
Article CAS PubMed Google Scholar
Giagtzoglou N., Ly C.V., Bellen H.J. 2009. Cell adhesion, the backbone of the synapse: “Vertebrate” and “invertebrate” perspectives. Cold Spring Harb. Perspect. Biol. 1 (4), a003079.
Article PubMed PubMed Central Google Scholar
Wegenast-Braun B.M., Maisch A.F., Eicke D., Radde R., Herzig M.C., Staufenbiel M., Jucker M., Calhoun M.E. 2009. Independent effects of intra- and extracellular a beta on learning-related gene expression. Am. J. Pathol. 175 (1), 271‒282.
Article CAS PubMed PubMed Central Google Scholar
Melchior B., Garcia A.E., Hsiung B.K., Lo K.M., Doose J.M., Thrash J.C., Stalder A.K., Staufenbiel M., Neumann H., Carson M.J. 2010. Dual induction of TREM2 and tolerance-related transcript, Tmem176b, in amyloid transgenic mice: Implications for vaccine-based therapies for Alzheimer’s disease. ASN Neuro. 2 (3), 157‒170.
Lehmann S.M., Kruger C., Park B., Derkow K., Rosenberger K., Baumgart J., Trimbuch T., Eom G., Hinz M., Kaul D., Habbel P., Kalin R., Franzoni E., Rybak A., Nguyen D., Veh R., Ninnemann O., Peters O., Nitsch R., Heppner F.L., Golenbock D., Schott E., Ploegh H.L., Wulczyn F.G., Lehnardt S. 2012. An unconventional role for miRNA: let-7 activates Toll-like receptor 7 and causes neurodegeneration. Nat. Neurosci. 15 (6), 827‒835.
Article CAS PubMed Google Scholar
Neve R.L., Valletta J.S., Li Y., Ventosa-Michelman M., Holtzman D.M., Mobley W.C. 1996. A comprehensive study of the spatiotemporal pattern of beta-amyloid precursor protein mRNA and protein in the rat brain: lack of modulation by exogenously applied nerve growth factor. Brain Res. Mol. Brain Res. 39 (1–2), 185‒197.
Article CAS PubMed Google Scholar
Aronov S., Aranda G., Behar L., Ginzburg I. 2001. Axonal tau mRNA localization coincides with tau protein in living neuronal cells and depends on axonal targeting signal. J. Neurosci. 21 (17), 6577‒6587.
Article CAS PubMed PubMed Central Google Scholar
Malmqvist T., Anthony K., Gallo J.M. 2014. Tau mRNA is present in axonal RNA granules and is associated with elongation factor 1A. Brain Res. 1584, 22‒27.
Article CAS PubMed Google Scholar
Page K., Hollister R., Tanzi R.E., Hyman B.T. 1996. In situ hybridization analysis of presenilin 1 mRNA in Alzheimer disease and in lesioned rat brain. Proc. Natl. Acad. Sci. U. S. A. 93 (24), 14020‒14024.
Article CAS PubMed PubMed Central Google Scholar
Irizarry M.C., Locascio J.J., Hyman B.T. 2001. β-Site APP cleaving enzyme mRNA expression in APP transgenic mice—anatomical overlap with transgene expression and static levels with aging. Am. J. Pathol. 158 (1), 173‒177.
Article CAS PubMed PubMed Central Google Scholar
Pardue S., White C.L., 3rd, Bigio E.H., Morrison-Bogorad M. 1994. Anomalous binding of radiolabeled oligonucleotide probes to plaques and tangles in Alzheimer disease hippocampus. Mol. Chem. Neuropathol. 22 (1), 1‒24.
Article CAS PubMed Google Scholar
Ginsberg S.D., Crino P.B., Lee V.M., Eberwine J.H., Trojanowski J.Q. 1997. Sequestration of RNA in Alzheimer’s disease neurofibrillary tangles and senile plaques. Ann. Neurol. 41 (2), 200‒209.
Article CAS PubMed Google Scholar
Radde R., Bolmont T., Kaeser S.A., Coomaraswamy J., Lindau D., Stoltze L., Calhoun M.E., Jäggi F., Wolburg H., Gengler S., Haass C., Ghetti B., Czech C., Hölscher C., Mathews P.M., Jucker M. 2006. Abeta42-driven cerebral amyloidosis in transgenic mice reveals early and robust pathology. EMBO Rep. 7 (9), 940‒946.
Article CAS PubMed PubMed Central Google Scholar
Redies C., Engelhart K., Takeichi M. 1993. Differential expression of N- and R-cadherin in functional neuronal systems and other structures of the developing chicken brain. J. Comp. Neurol. 333 (3), 398‒416.
Article CAS PubMed Google Scholar
Yamasaki A., Eimer S., Okochi M., Smialowska A., Kaether C., Baumeister R., Haass C., Steiner H. 2006. The GxGD motif of presenilin contributes to catalytic function and substrate identification of gamma-secretase. J. Neurosci. 26 (14), 3821‒3828.
Article CAS PubMed PubMed Central Google Scholar
Marcinkiewicz M. 2002. beta APP and furin mRNA concentrates in immature senile plaques in the brain of Alzheimer patients. J. Neuropathol. Exp. Neurol. 61 (9), 815‒829.
Article CAS PubMed Google Scholar
Gouras G.K., Almeida C.G., Takahashi R.H. 2005. Intraneuronal Abeta accumulation and origin of plaques in Alzheimer’s disease. Neurobiol. Aging. 26 (9), 1235‒1244.
Article CAS PubMed Google Scholar
Friedrich R.P., Tepper K., Roznicke R., Soom M., Westermann M., Reymann K., Kaether C., Fandrich M. 2010. Mechanism of amyloid plaque formation suggests an intracellular basis of A beta pathogenicity. Proc. Natl. Acad. Sci. U. S. A. 107 (5), 1942‒1947.
Article CAS PubMed PubMed Central Google Scholar
Ginsberg S.D., Crino P.B., Hemby S.E., Weingarten J.A., Lee V.M.Y., Eberwine J.H., Trojanowski J.Q. 1999. Predominance of neuronal m-RNAs in individual Alzheimer’s disease senile plaques. Ann. Neurol. 45 (2), 174‒181.
Article CAS PubMed Google Scholar
Ginsberg S.D., Alldred M.J., Che S.L. 2012. Gene expression levels assessed by CA1 pyramidal neuron and regional hippocampal dissections in Alzheimer’s disease. Neurobiol. Dis. 45 (1), 99‒107.
Article CAS PubMed Google Scholar
Uehara Y., Yamada T., Baba Y., Miura S.I., Abe S., Kitajima K., Higuchi M.A., Iwamoto T., Saku K. 2008. ATP-binding cassette transporter G4 is highly expressed in microglia in Alzheimer’s brain. Brain Res. 1217, 239‒246.
Article CAS PubMed Google Scholar
Westmark C.J., Malter J.S. 2007. FMRP mediates mGluR(5)-dependent translation of amyloid precursor protein. Plos Biol. 5 (3), 629‒639.
Rogers J.T., Bush A.I., Cho H.H., Smith D.H., Thomson A.M., Friedlich A.L., Lahiri D.K., Leedman P.J., Huang X.D., Cahill C.M. 2008. Iron and the translation of the amyloid precursor protein (APP) and ferritin mRNAs: Riboregulation against neural oxidative damage in Alzheimer’s disease. Biochem. Soc. Transact. 36, 1282‒1287.
Dona F., Houseley J. 2014. Unexpected DNA loss mediated by the DNA binding activity of ribonuclease A. PLoS One. 9 (12), e115008.
Article PubMed PubMed Central Google Scholar
Chartrand P., Bertrand E., Singer R.H., Long R.M. 2000. Sensitive and high-resolution detection of RNA in situ. In RNA-Ligand Interactions, Part B: Molecular Biology Methods. Celander D.W., Abelson J.N., Eds. Methods Enzymol. 318, 493‒506.
King O.D., Gitler A.D., Shorter J. 2012. The tip of the iceberg: RNA-binding proteins with prion-like domains in neurodegenerative disease. Brain Res. 1462, 61‒80.
Article CAS PubMed PubMed Central Google Scholar
Mathura V.S., Paris D., Ait-Ghezala G., Quadros A., Patel N.S., Kolippakkam D.N., Volmar C.H., Mullan M.J. 2005. Model of Alzheimer’s disease amyloid-beta peptide based on a RNA binding protein. Biochem. Biophys.Res. Commun. 332 (2), 585‒592.
Article CAS PubMed Google Scholar
Chen J.W., Newhall J., Xie Z.R., Leckband D., Wu Y.H. 2016. A computational model for kinetic studies of cadherin binding and clustering. Biophys. J. 111 (7), 1507‒1518.
Article CAS PubMed PubMed Central Google Scholar
Mills F., Globa A.K., Liu S., Cowan C.M., Mobasser M., Phillips A.G., Borgland S.L., Bamji S.X. 2017. Cadherins mediate cocaine-induced synaptic plasticity and behavioral conditioning. Nat. Neurosci. 20 (4), 540‒549.
留言 (0)