Bray F, Ferlay J, Soerjomataram I, et al. Global cancer statistics 2018: GLOBOCAN estimates of incidence and mortality worldwide for 36 cancers in 185 countries. CA Cancer J Clin. 2018;68:394–424

Article  PubMed  Google Scholar 

Chen W, Zheng R, Baade PD, et al. Cancer statistics in China, 2015. CA Cancer J Clin. 2016;66:115–132

Article  PubMed  Google Scholar 

Engstrand J, Nilsson H, Stromberg C, et al. Colorectal cancer liver metastases—a population-based study on incidence, management and survival. BMC Cancer. 2018;18:78

Article  PubMed  PubMed Central  Google Scholar 

Reboux N, Jooste V, Goungounga J, et al. Incidence and survival in synchronous and metachronous liver metastases from colorectal cancer. JAMA Netw Open. 2022;5: e2236666

Article  PubMed  PubMed Central  Google Scholar 

Osterlund P, Salminen T, Soveri LM, et al. Repeated centralized multidisciplinary team assessment of resectability, clinical behavior, and outcomes in 1086 Finnish metastatic colorectal cancer patients (RAXO): a nationwide prospective intervention study. Lancet Reg Health Eur. 2021;3: 100049

Article  PubMed  PubMed Central  Google Scholar 

Liu W, Liu JM, Wang K, et al. Recurrent colorectal liver metastasis patients could benefit from repeat hepatic resection. BMC Surg. 2021;21:327

Article  PubMed  PubMed Central  Google Scholar 

Berardi G, Chou J, Gonen M, et al. A model to predict treatment failure in patients undergoing upfront surgery for resectable colorectal liver metastases. Ann Surg Oncol. 2023;30:2820–2827

Article  PubMed  Google Scholar 

Rhaiem R, Rached L, Tashkandi A, et al. Implications of RAS mutations on oncological outcomes of surgical resection and thermal ablation techniques in the treatment of colorectal liver metastases. Cancers (Basel). 2022;14:816

Article  PubMed  Google Scholar 

Cervantes A, Adam R, Rosello S, et al. Metastatic colorectal cancer: ESMO Clinical Practice Guideline for diagnosis, treatment and follow-up. Ann Oncol. 2023;34:10–32

Article  CAS  PubMed  Google Scholar 

Rubbia-Brandt L, Giostra E, Brezault C, et al. Importance of histological tumor response assessment in predicting the outcome in patients with colorectal liver metastases treated with neo-adjuvant chemotherapy followed by liver surgery. Ann Oncol. 2007;18:299–304

Article  CAS  PubMed  Google Scholar 

Blazer DG 3rd, Kishi Y, Maru DM, et al. Pathologic response to preoperative chemotherapy: a new outcome end point after resection of hepatic colorectal metastases. J Clin Oncol. 2008;26:5344–5351

Article  PubMed  Google Scholar 

Takahashi T, Ishida K, Emi Y, et al. Pathological evaluation of resected colorectal liver metastases: mFOLFOX6 plus bevacizumab versus mFOLFOX6 plus cetuximab in the phase II ATOM trial. Cancers (Basel). 2022;14:4392

Article  CAS  PubMed  Google Scholar 

Mason MC, Krasnodebski M, Hester CA, et al. Outcomes of mixed pathologic response in patients with multiple colorectal liver metastases treated with neoadjuvant chemotherapy and liver resection. Ann Surg Oncol. 2022;29:5156–5164

Article  PubMed  Google Scholar 

Xu Y, He J, Li W, et al. The pathologic complete response ratio of liver metastases represents a valuable prognostic indicator. Pathol Oncol Res. 2022;28: 1610663

Article  PubMed  PubMed Central  Google Scholar 

Xu D, Wang YY, Yan XL, et al. Development of a model to predict pathologic response to chemotherapy in patients with colorectal liver metastases. J Gastrointest Oncol. 2021;12:1498–1508

Article  PubMed  PubMed Central  Google Scholar 

Zhu HB, Xu D, Ye M, et al. Deep learning-assisted magnetic resonance imaging prediction of tumor response to chemotherapy in patients with colorectal liver metastases. Int J Cancer. 2021;148:1717–1730

Article  CAS  PubMed  Google Scholar 

Adams AM, Vreeland TJ, Newhook TE. Circulating tumor DNA: towards more individualized treatment for patients with resectable colorectal cancer. J Gastrointest Cancer. 2023;54:1071–1081

Article  CAS  PubMed  Google Scholar 

Marmorino F, Prisciandaro M, Giordano M, et al. Circulating tumor DNA as a marker of minimal residual disease after radical resection of colorectal liver metastases. JCO Precis Oncol. 2022;6: e2200244

Article  PubMed  Google Scholar 

Newhook TE, Overman MJ, Chun YS, et al. Prospective study of perioperative circulating tumor DNA dynamics in patients undergoing hepatectomy for colorectal liver metastases. Ann Surg. 2023;277:813–820

Article  PubMed  Google Scholar 

Wang DS, Yang H, Liu XY, et al. Dynamic monitoring of circulating tumor DNA to predict prognosis and efficacy of adjuvant chemotherapy after resection of colorectal liver metastases. Theranostics. 2021;11:7018–7028

Article  CAS  PubMed  PubMed Central  Google Scholar 

Ogaard N, Reinert T, Henriksen TV, et al. Tumour-agnostic circulating tumour DNA analysis for improved recurrence surveillance after resection of colorectal liver metastases: a prospective cohort study. Eur J Cancer. 2022;163:163–176

Article  PubMed  Google Scholar 

Evrard S, Torzilli G, Caballero C, et al. Parenchymal sparing surgery brings treatment of colorectal liver metastases into the precision medicine era. Eur J Cancer. 2018;104:195–200

Article  PubMed  Google Scholar 

Liu M, Wang Y, Wang K, et al. Combined ablation and resection (CARe) for resectable colorectal cancer liver metastases—a propensity score matching study. Eur J Surg Oncol. 2023;49: 106931

Article  PubMed  Google Scholar 

Liu W, Jin KM, Zhang MH, et al. Recurrence prediction by circulating tumor DNA in the patient with colorectal liver metastases after hepatectomy: a prospective biomarker study. Ann Surg Oncol. 2023;30:4916–4926

Article  PubMed  Google Scholar 

Reinert T, Petersen LMS, Henriksen TV, et al. Circulating tumor DNA for prognosis assessment and postoperative management after curative-intent resection of colorectal liver metastases. Int J Cancer. 2022;150:1537–1548

Article  CAS  PubMed  PubMed Central  Google Scholar 

Tie J, Wang Y, Cohen J, et al. Circulating tumor DNA dynamics and recurrence risk in patients undergoing curative intent resection of colorectal cancer liver metastases: a prospective cohort study. PLoS Med. 2021;18: e1003620

Article  CAS  PubMed  PubMed Central  Google Scholar 

Kobayashi S, Nakamura Y, Taniguchi H, et al. Impact of preoperative circulating tumor DNA status on survival outcomes after hepatectomy for resectable colorectal liver metastases. Ann Surg Oncol. 2021;28:4744–4755

Article  PubMed  Google Scholar 

Bidard FC, Kiavue N, Ychou M, et al. Circulating tumor cells and circulating tumor DNA detection in potentially resectable metastatic colorectal cancer: a prospective ancillary study to the Unicancer Prodige-14 trial. Cells. 2019;8:516

Article  CAS  PubMed  PubMed Central  Google Scholar 

Vega EA, Salehi O, Nicolaescu D, et al. Failure to cure patients with colorectal liver metastases: the impact of the liver surgeon. Ann Surg Oncol. 2021;28:7698–7706

Article  PubMed  Google Scholar 

Xu D, Yan XL, Liu JM, et al. The characteristics and long-term survival of patients with colorectal liver metastases with pathological complete response after chemotherapy. J Cancer. 2020;11:6256–6263

Article  CAS  PubMed  PubMed Central  Google Scholar 

Huang Y, Jia W, Wang L, et al. Clearance of circulating tumor DNA in a high-risk stage-IV rectal carcinoma patient with synchronous liver metastases after conversion surgery is correlated with pathologic complete response. Ther Adv Gastrointest Endosc. 2021;14: 26317745211020279

PubMed  PubMed Central  Google Scholar