ZNF787 and HDAC1 Mediate Blood–Brain Barrier Permeability in an In Vitro Model of Alzheimer’s Disease Microenvironment

Adhikari N, Amin SA, Trivedi P, Jha T, Ghosh B (2018) HDAC3 is a potential validated target for cancer: an overview on the benzamide-based selective HDAC3 inhibitors through comparative SAR/QSAR/QAAR approaches. Eur J Med Chem 157:1127–1142. https://doi.org/10.1016/j.ejmech.2018.08.081

Article  CAS  PubMed  Google Scholar 

Al-Edresi S, Alsalahat I, Freeman S, Aojula H, Penny J (2020) Resveratrol-mediated cleavage of amyloid beta(1–42) peptide: potential relevance to Alzheimer’s disease. Neurobiol Aging 94:24–33. https://doi.org/10.1016/j.neurobiolaging.2020.04.012

Article  CAS  PubMed  Google Scholar 

Armulik A, Genove G, Mae M, Nisancioglu MH, Wallgard E, Niaudet C, He L, Norlin J, Lindblom P, Strittmatter K et al (2010) Pericytes regulate the blood-brain barrier. Nature 468:557–561. https://doi.org/10.1038/nature09522

Article  ADS  CAS  PubMed  Google Scholar 

Blind RD (2020) Structural analyses of inositol phosphate second messengers bound to signaling effector proteins. Adv Biol Regul 75:100667. https://doi.org/10.1016/j.jbior.2019.100667

Article  CAS  PubMed  Google Scholar 

Boyer-Di Ponio J, El-Ayoubi F, Glacial F, Ganeshamoorthy K, Driancourt C, Godet M, Perriere N, Guillevic O, Couraud PO, Uzan G (2014) Instruction of circulating endothelial progenitors in vitro towards specialized blood-brain barrier and arterial phenotypes. PLoS ONE 9:e84179. https://doi.org/10.1371/journal.pone.0084179

Article  ADS  CAS  PubMed  Google Scholar 

Burkhart A, Thomsen LB, Thomsen MS, Lichota J, Fazakas C, Krizbai I, Moos T (2015) Transfection of brain capillary endothelial cells in primary culture with defined blood-brain barrier properties. Fluids Barriers CNS 12:19. https://doi.org/10.1186/s12987-015-0015-9

Article  CAS  PubMed  PubMed Central  Google Scholar 

Cai Z, Qiao PF, Wan CQ, Cai M, Zhou NK, Li Q (2018) Role of blood-brain barrier in Alzheimer’s disease. J Alzheimers Dis 63:1223–1234. https://doi.org/10.3233/JAD-180098

Article  CAS  PubMed  Google Scholar 

Chan Y, Chen W, Chen Y, Lv Z, Wan W, Li Y, Zhang C (2020) Yi-Zhi-Fang-Dai formula exerts a protective effect on the injury of tight junction scaffold proteins in vitro and in vivo by mediating autophagy through regulation of the RAGE/CaMKKbeta/AMPK/mTOR pathway. Biol Pharm Bull 43:1847–1858. https://doi.org/10.1248/bpb.b20-00379

Article  CAS  PubMed  Google Scholar 

Chen JS, Wang HK, Hsu CY, Su YT, Chen JS, Liang CL, Hsieh PC, Wu CC, Kwan AL (2021) HDAC1 deregulation promotes neuronal loss and deficit of motor function in stroke pathogenesis. Sci Rep 11:16354. https://doi.org/10.1038/s41598-021-95837-3

Article  ADS  CAS  PubMed  PubMed Central  Google Scholar 

Cheng Z, Zou X, Jin Y, Gao S, Lv J, Li B, Cui R (2018) The role of KLF(4) in Alzheimer’s disease. Front Cell Neurosci 12:325. https://doi.org/10.3389/fncel.2018.00325

Article  CAS  PubMed  PubMed Central  Google Scholar 

Costea L, Meszaros A, Bauer H, Bauer HC, Traweger A, Wilhelm I, Farkas AE, Krizbai IA (2019) The blood-brain barrier and its intercellular junctions in age-related brain disorders. Int J Mol Sci 20:5472. https://doi.org/10.3390/ijms20215472

Article  CAS  PubMed  PubMed Central  Google Scholar 

Daneman R, Prat A (2015) The blood-brain barrier. Cold Spring Harb Perspect Biol 7:a020412. https://doi.org/10.1101/cshperspect.a020412

Article  PubMed  PubMed Central  Google Scholar 

Dudek KA, Dion-Albert L, Lebel M, LeClair K, Labrecque S, Tuck E, Ferrer Perez C, Golden SA, Tamminga C, Turecki G et al (2020) Molecular adaptations of the blood-brain barrier promote stress resilience vs. depression. Proc Natl Acad Sci U S A 117:3326–3336. https://doi.org/10.1073/pnas.1914655117

Article  ADS  CAS  PubMed  PubMed Central  Google Scholar 

Dunaway LS, Pollock JS (2022) HDAC1: an environmental sensor regulating endothelial function. Cardiovasc Res 118:1885–1903. https://doi.org/10.1093/cvr/cvab198

Article  CAS  PubMed  Google Scholar 

Galea I (2021) The blood-brain barrier in systemic infection and inflammation. Cell Mol Immunol 18:2489–2501. https://doi.org/10.1038/s41423-021-00757-x

Article  CAS  PubMed  PubMed Central  Google Scholar 

Gao Y, Zhang N, Lv C, Li N, Li X, Li W (2020) lncRNA SNHG1 Knockdown alleviates amyloid-beta-induced neuronal injury by regulating ZNF217 via sponging miR-361-3p in Alzheimer’s disease. J Alzheimers Dis 77:85–98. https://doi.org/10.3233/JAD-191303

Article  CAS  PubMed  Google Scholar 

Graff J, Tsai LH (2013) The potential of HDAC inhibitors as cognitive enhancers. Annu Rev Pharmacol Toxicol 53:311–330. https://doi.org/10.1146/annurev-pharmtox-011112-140216

Article  CAS  PubMed  Google Scholar 

Han J, Li JH, Bai G, Shen GS, Chen J, Liu JN, Wang S, Liu XJ (2017) Acanthopanax senticosus polysaccharides-induced intestinal tight junction injury alleviation via inhibition of NF-kappaB/MLCK pathway in a mouse endotoxemia model. World J Gastroenterol 23:2175–2184. https://doi.org/10.3748/wjg.v23.i12.2175

Article  CAS  PubMed  PubMed Central  Google Scholar 

Hardy J, Selkoe DJ (2002) The amyloid hypothesis of Alzheimer’s disease: progress and problems on the road to therapeutics. Science 297:353–356. https://doi.org/10.1126/science.1072994

Article  ADS  CAS  PubMed  Google Scholar 

He J, Xue Y, Wang Q, Zhou X, Liu L, Zhang T, Shang C, Ma J, Ma T (2020) Long non-coding RNA MIAT regulates blood tumor barrier permeability by functioning as a competing endogenous RNA. Cell Death Dis 11:936. https://doi.org/10.1038/s41419-020-03134-0

Article  CAS  PubMed  PubMed Central  Google Scholar 

Ho TCS, Chan AHY, Ganesan A (2020) Thirty years of HDAC inhibitors: 2020 insight and hindsight. J Med Chem 63:12460–12484. https://doi.org/10.1021/acs.jmedchem.0c00830

Article  CAS  PubMed  Google Scholar 

Hou Q, Ruan H, Gilbert J, Wang G, Ma Q, Yao WD, Man HY (2015) MicroRNA miR124 is required for the expression of homeostatic synaptic plasticity. Nat Commun 6:10045. https://doi.org/10.1038/ncomms10045

Article  ADS  CAS  PubMed  Google Scholar 

Hu C, Peng K, Wu Q, Wang Y, Fan X, Zhang DM, Passerini AG, Sun C (2021) HDAC1 and 2 regulate endothelial VCAM-1 expression and atherogenesis by suppressing methylation of the GATA6 promoter. Theranostics 11:5605–5619. https://doi.org/10.7150/thno.55878

Article  CAS  PubMed  PubMed Central  Google Scholar 

Huang J, Zhu Z, Ji D, Sun R, Yang Y, Liu L, Shao Y, Chen Y, Li L, Sun B (2021) Single-cell transcriptome profiling reveals neutrophil heterogeneity and functional multiplicity in the early stage of severe burn patients. Front Immunol 12:792122. https://doi.org/10.3389/fimmu.2021.792122

Article  CAS  PubMed  Google Scholar 

Ishii M, Iadecola C (2020) Risk factor for Alzheimer’s disease breaks the blood-brain barrier. Nature 581:31–32. https://doi.org/10.1038/d41586-020-01152-8

Article  ADS  CAS  PubMed  PubMed Central  Google Scholar 

Jiang L, Yin M, Wei X, Liu J, Wang X, Niu C, Kang X, Xu J, Zhou Z, Sun S et al (2015) Bach1 represses Wnt/beta-catenin signaling and angiogenesis. Circ Res 117:364–375. https://doi.org/10.1161/CIRCRESAHA.115.306829

Article  CAS  PubMed  PubMed Central  Google Scholar 

Kashio T, Shirakura K, Kinoshita M, Morita M, Ishiba R, Muraoka K, Kanbara T, Tanaka M, Funatsu R, Hino N et al (2021) HDAC inhibitor, MS-275, increases vascular permeability by suppressing Robo4 expression in endothelial cells. Tissue Barriers 9:1911195. https://doi.org/10.1080/21688370.2021.1911195

Article  CAS  PubMed  PubMed Central  Google Scholar 

Konsoula Z, Barile FA (2012) Epigenetic histone acetylation and deacetylation mechanisms in experimental models of neurodegenerative disorders. J Pharmacol Toxicol Methods 66:215–220. https://doi.org/10.1016/j.vascn.2012.08.001

Article  CAS  PubMed  Google Scholar 

Kutsche LK, Gysi DM, Fallmann J, Lenk K, Petri R, Swiersy A, Klapper SD, Pircs K, Khattak S, Stadler PF et al (2018) Combined experimental and system-level analyses reveal the complex regulatory network of miR-124 during human neurogenesis. Cell Syst 7:438–452. https://doi.org/10.1016/j.cels.2018.08.011

Article  CAS  PubMed  PubMed Central  Google Scholar 

Li H, Hong G, Lin M, Shi Y, Wang L, Jiang F, Zhang F, Wang Y, Guo Z (2017a) Identification of molecular alterations in leukocytes from gene expression profiles of peripheral whole blood of Alzheimer’s disease. Sci Rep 7:14027. https://doi.org/10.1038/s41598-017-13700-w

Article  ADS  CAS 

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