Andrews L, Keller SS, Osman-Farah J, Macerollo A (2023) A structural magnetic resonance imaging review of clinical motor outcomes from deep brain stimulation in movement disorders. Brain Commun 5:fcad171

Article  PubMed  PubMed Central  Google Scholar 

Bai X, Zhang X, Fang R, Wang J, Ma Y, Liu Z, Dong H, Li Q, Ge J, Yu M, Fei J, Sun R, Huang F (2021) Deficiency of miR-29b2/c leads to accelerated aging and neuroprotection in MPTP-induced Parkinson’s disease mice. Aging (albany NY) 13:22390–22411

Article  CAS  PubMed  Google Scholar 

Berger A, Le Fourn V, Masternak J, Regamey A, Bodenmann I, Girod PA, Mermod N (2020) Overexpression of transcription factor Foxa1 and target genes remediate therapeutic protein production bottlenecks in Chinese hamster ovary cells. Biotechnol Bioeng 117:1101–1116

Article  CAS  PubMed  PubMed Central  Google Scholar 

Blaudin de The FX, Rekaik H, Prochiantz A, Fuchs J, Joshi RL (2016) Neuroprotective transcription factors in animal models of Parkinson disease. Neural Plast 2016:6097107

Article  PubMed  Google Scholar 

Cai LJ, Tu L, Huang XM, Huang J, Qiu N, Xie GH, Liao JX, Du W, Zhang YY, Tian JY (2020) LncRNA MALAT1 facilitates inflammasome activation via epigenetic suppression of Nrf2 in Parkinson’s disease. Mol Brain 13:130

Article  CAS  PubMed  PubMed Central  Google Scholar 

Chen H, Teng Y, Chen X, Liu Z, Geng F, Liu Y, Jiang H, Wang Z, Yang L (2021) Platelet-derived growth factor (PDGF)-BB protects dopaminergic neurons via activation of Akt/ERK/CREB pathways to upregulate tyrosine hydroxylase. CNS Neurosci Ther 27:1300–1312

Article  CAS  PubMed  PubMed Central  Google Scholar 

Costa LG, de Laat R, Dao K, Pellacani C, Cole TB, Furlong CE (2014) Paraoxonase-2 (PON2) in brain and its potential role in neuroprotection. Neurotoxicology 43:3–9

Article  CAS  PubMed  Google Scholar 

Das S, Mondal A, Dey C, Chakraborty S, Bhowmik R, Karmakar S, Sengupta A (2023) ER stress induces upregulation of transcription factor Tbx20 and downstream Bmp2 signaling to promote cardiomyocyte survival. J Biol Chem 299:103031

Article  CAS  PubMed  PubMed Central  Google Scholar 

Devarajan A, Grijalva VR, Bourquard N, Meriwether D 3rd, Imaizumi S, Shin BC, Devaskar SU, Reddy ST (2012) Macrophage paraoxonase 2 regulates calcium homeostasis and cell survival under endoplasmic reticulum stress conditions and is sufficient to prevent the development of aggravated atherosclerosis in paraoxonase 2 deficiency/apoE-/- mice on a Western diet. Mol Genet Metab 107:416–427

Article  CAS  PubMed  PubMed Central  Google Scholar 

Devarajan A, Shih D, Reddy ST (2014) Inflammation, infection, cancer and all that...the role of paraoxonases. Adv Exp Med Biol 824:33–41

Article  CAS  PubMed  PubMed Central  Google Scholar 

Elsworth JD (2020) Parkinson’s disease treatment: Past, present, and future. J Neural Transm (vienna) 127:785–791

Article  PubMed  Google Scholar 

Fernandez-Santiago R, Carballo-Carbajal I, Castellano G, Torrent R, Richaud Y, Sanchez-Danes A, Vilarrasa-Blasi R, Sanchez-Pla A, Mosquera JL, Soriano J, Lopez-Barneo J, Canals JM, Alberch J, Raya A, Vila M, Consiglio A, Martin-Subero JI, Ezquerra M, Tolosa E (2015) Aberrant epigenome in iPSC-derived dopaminergic neurons from Parkinson’s disease patients. EMBO Mol Med 7:1529–1546

Article  CAS  PubMed  PubMed Central  Google Scholar 

Friedman JR, Kaestner KH (2006) The Foxa family of transcription factors in development and metabolism. Cell Mol Life Sci 63:2317–2328

Article  CAS  PubMed  PubMed Central  Google Scholar 

Furlong CE, Marsillach J, Jarvik GP, Costa LG (2016) Paraoxonases-1, -2 and -3: What are their functions? Chem Biol Interact 259:51–62

Article  CAS  PubMed  PubMed Central  Google Scholar 

Garrick JM, Dao K, de Laat R, Elsworth J, Cole TB, Marsillach J, Furlong CE, Costa LG (2016) Developmental expression of paraoxonase 2. Chem Biol Interact 259:168–174

Article  CAS  PubMed  PubMed Central  Google Scholar 

Giordano G, Cole TB, Furlong CE, Costa LG (2011) Paraoxonase 2 (PON2) in the mouse central nervous system: A neuroprotective role? Toxicol Appl Pharmacol 256:369–378

Article  CAS  PubMed  PubMed Central  Google Scholar 

Han CC, Wan FS (2018) New insights into the role of endoplasmic reticulum stress in breast cancer metastasis. J Breast Cancer 21:354–362

Article  PubMed  PubMed Central  Google Scholar 

Hayes MT (2019) Parkinson’s disease and parkinsonism. Am J Med 132:802–807

Article  PubMed  Google Scholar 

Hetz C, Saxena S (2017) ER stress and the unfolded protein response in neurodegeneration. Nat Rev Neurol 13:477–491

Article  CAS  PubMed  Google Scholar 

Horke S, Witte I, Wilgenbus P, Kruger M, Strand D, Forstermann U (2007) Paraoxonase-2 reduces oxidative stress in vascular cells and decreases endoplasmic reticulum stress-induced caspase activation. Circulation 115:2055–2064

Article  CAS  PubMed  Google Scholar 

Horke S, Witte I, Wilgenbus P, Altenhofer S, Kruger M, Li H, Forstermann U (2008) Protective effect of paraoxonase-2 against endoplasmic reticulum stress-induced apoptosis is lost upon disturbance of calcium homoeostasis. Biochem J 416:395–405

Article  CAS  PubMed  Google Scholar 

Jhuo CF, Hsieh SK, Chen CJ, Chen WY, Tzen JTC (2020) Teaghrelin protects SH-SY5Y cells against MPP(+)-induced neurotoxicity through activation of AMPK/SIRT1/PGC-1alpha and ERK1/2 pathways. Nutrients 12:3665

Article  CAS  PubMed  PubMed Central  Google Scholar 

Jin W (2020) Regulation of BDNF-TrkB signaling and potential therapeutic strategies for Parkinson’s disease. J Clin Med 9:257

Article  CAS  PubMed  PubMed Central  Google Scholar 

Kumari M, Ramdas P, Radhakrishnan AK, Kutty MK, Haleagrahara N (2021) Tocotrienols ameliorate neurodegeneration and motor deficits in the 6-OHDA-induced rat model of parkinsonism behavioural and immunohistochemistry analysis. Nutrients 13:1583

Article  CAS  PubMed  PubMed Central  Google Scholar 

Kovaleva V, Saarma M (2021) Endoplasmic reticulum stress regulators: New drug targets for Parkinson’s disease. J Parkinsons Dis 11:S219–S228

Article  CAS  PubMed  PubMed Central  Google Scholar 

Li B, An D, Zhu S (2022) PBX1 attenuates 6-OHDA-induced oxidative stress and apoptosis and affects PINK1/PARKIN expression in dopaminergic neurons via FOXA1. Cytotechnology 74:217–229

Article  CAS  PubMed  PubMed Central  Google Scholar 

Li M, Zhang J, Jiang L, Wang W, Feng X, Liu M, Yang D (2023) Neuroprotective effects of morroniside from Cornus officinalis sieb. Et Zucc against Parkinson’s Disease via Inhibiting Oxidative Stress and Ferroptosis, BMC Complement Med Ther 23:218

CAS  PubMed  Google Scholar 

Liang T, Zhao P, Zhang X, Han X, Hong B, Kong L, Chang H, Liu L (2022) FOXA1 transcription activates TFF1 to reduce 6-OHDA-induced dopaminergic neuron damage. Exp Ther Med 23:372

Article  CAS  PubMed  PubMed Central