MeSH 搜索器

Ectodysplasins

Transmembrane proteins belonging to the tumor necrosis factor superfamily that play an essential role in the normal development of several ectodermally derived organs. Several isoforms of the ectodysplasins exist due to multiple ALTERNATIVE SPLICING of the MRNA for the protein. The isoforms ectodysplasin A1 and ectodysplasin A2 are considered biologically active and each bind distinct ECTODYSPLASIN RECEPTORS. Genetic mutations that result in loss of function of ectodysplasin result in ECTODERMAL DYSPLASIA 1, ANHIDROTIC.
推出的年份: 2007(1999)
副标题
树号: D12.644.276.374.750.186, D12.776.395.550.275, D12.776.467.374.750.186, D12.776.543.550.275, D23.529.374.750.186
MeSH 单一 ID: D053331
进入的组:
  • Ectodysplasin-A
  • Ectodysplasin A
  • Ectodysplasin
  • Ectodysplasin A, Isoform 2
  • Ectodysplasin A2
  • Ectodysplasin A, Isoform 1
  • Ectodysplasin A1

留言 (0)

沒有登入
gif