MeSH 搜索器

AC133 Antigen

A member of the prominin family, AC133 Antigen is a 5-transmembrane antigen occurring as several isoforms produced by alternative splicing which are processed into mature forms. In humans, it is expressed as a subset of CD34 (bright) human hematopoietic stem cells and CD34 positive leukemias. Functionally, it is associated with roles in cell differentiation, proliferation, and apoptosis. Specifically, it regulates the organization of apical plasma membrane in epithelial cells, disk morphogenesis during early retinal development, MAPK and Akt signaling pathways, and in cholesterol metabolism.
推出的年份: 2017(1998)
副标题
树号: D12.776.395.550.007, D12.776.543.550.023
MeSH 单一 ID: D000071916
进入的组:
  • Antigen, AC133
  • CD133 Antigen
  • Antigen, CD133
  • PROML1
  • Prominin
  • Prominin-1
  • Prominin 1
  • Prominin-Like PROML1
  • Prominin Like PROML1
  • AC133-1 Antigen
  • AC133 1 Antigen
  • Antigen, AC133-1
  • Fudenine
  • AC141 Antigen
  • Antigen, AC141
  • AC133-2 Antigen
  • AC133 2 Antigen
  • Antigen, AC133-2

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