Tumor Necrosis Factor-alpha

Serum glycoprotein produced by activated MACROPHAGES and other mammalian MONONUCLEAR LEUKOCYTES. It has necrotizing activity against tumor cell lines and increases ability to reject tumor transplants. Also known as TNF-alpha, it is only 30% homologous to TNF-beta (LYMPHOTOXIN), but they share TNF RECEPTORS.

推出的年份: 2005(1988)

树号: D12.644.276.374.500.800, D12.644.276.374.750.626, D12.776.124.900, D12.776.395.930, D12.776.467.374.500.800, D12.776.467.374.750.626, D23.529.374.500.800, D23.529.374.750.626

MeSH 单一 ID: D014409

进入的组:

Tumor Necrosis Factor alpha
Cachectin
Cachectin-Tumor Necrosis Factor
Cachectin Tumor Necrosis Factor
Tumor Necrosis Factor Ligand Superfamily Member 2
Tumor Necrosis Factor
TNF Superfamily, Member 2
TNFalpha
TNF-alpha

早前的内容:

Endotoxins (1975-1987)
Glycoproteins (1975-1987)
Necrosis (1975-1987)

All MeSH Categories
- Chemicals and Drugs Category
  - Amino Acids, Peptides, and Proteins [D12]
    - Peptides [D12.644]
      - Intercellular Signaling Peptides and Proteins [D12.644.276]
        
        Cytokines [D12.644.276.374]
        
        Monokines [D12.644.276.374.500]
        
        Interleukin-1 [D12.644.276.374.500.400] add_circle
        
        Tumor Necrosis Factor-alpha [D12.644.276.374.500.800]

All MeSH Categories
- Chemicals and Drugs Category
  - Amino Acids, Peptides, and Proteins [D12]
    - Peptides [D12.644]
      - Intercellular Signaling Peptides and Proteins [D12.644.276]
        
        Cytokines [D12.644.276.374]
        
        Tumor Necrosis Factors [D12.644.276.374.750]
        
        4-1BB Ligand [D12.644.276.374.750.065]
        
        B-Cell Activating Factor [D12.644.276.374.750.061]
        
        CD27 Ligand [D12.644.276.374.750.030]
        
        CD30 Ligand [D12.644.276.374.750.092]
        
        CD40 Ligand [D12.644.276.374.750.124]
        
        Cytokine TWEAK [D12.644.276.374.750.155]
        
        Ectodysplasins [D12.644.276.374.750.186]
        
        Fas Ligand Protein [D12.644.276.374.750.249]
        
        Lymphotoxin alpha1, beta2 Heterotrimer [D12.644.276.374.750.505]
        
        Lymphotoxin-alpha [D12.644.276.374.750.500]
        
        Lymphotoxin-beta [D12.644.276.374.750.515]
        
        OX40 Ligand [D12.644.276.374.750.531]
        
        RANK Ligand [D12.644.276.374.750.562]
        
        TNF-Related Apoptosis-Inducing Ligand [D12.644.276.374.750.625]
        
        Tumor Necrosis Factor Ligand Superfamily Member 13 [D12.644.276.374.750.656]
        
        Tumor Necrosis Factor Ligand Superfamily Member 14 [D12.644.276.374.750.690]
        
        Tumor Necrosis Factor Ligand Superfamily Member 15 [D12.644.276.374.750.720]
        
        Tumor Necrosis Factor-alpha [D12.644.276.374.750.626]

All MeSH Categories
- Chemicals and Drugs Category
  - Amino Acids, Peptides, and Proteins [D12]
    - Proteins [D12.776]
      - Blood Proteins [D12.776.124]

All MeSH Categories
- Chemicals and Drugs Category
  - Amino Acids, Peptides, and Proteins [D12]
    - Proteins [D12.776]
      - Glycoproteins [D12.776.395]

All MeSH Categories
- Chemicals and Drugs Category
  - Amino Acids, Peptides, and Proteins [D12]
    - Proteins [D12.776]
      - Intercellular Signaling Peptides and Proteins [D12.776.467]
        
        Cytokines [D12.776.467.374]
        
        Monokines [D12.776.467.374.500]
        
        Interleukin-1 [D12.776.467.374.500.400] add_circle
        
        Tumor Necrosis Factor-alpha [D12.776.467.374.500.800]

All MeSH Categories
- Chemicals and Drugs Category
  - Amino Acids, Peptides, and Proteins [D12]
    - Proteins [D12.776]
      - Intercellular Signaling Peptides and Proteins [D12.776.467]
        
        Cytokines [D12.776.467.374]
        
        Tumor Necrosis Factors [D12.776.467.374.750]
        
        4-1BB Ligand [D12.776.467.374.750.065]
        
        B-Cell Activating Factor [D12.776.467.374.750.061]
        
        CD27 Ligand [D12.776.467.374.750.030]
        
        CD30 Ligand [D12.776.467.374.750.092]
        
        CD40 Ligand [D12.776.467.374.750.124]
        
        Cytokine TWEAK [D12.776.467.374.750.155]
        
        Ectodysplasins [D12.776.467.374.750.186]
        
        Fas Ligand Protein [D12.776.467.374.750.249]
        
        Lymphotoxin alpha1, beta2 Heterotrimer [D12.776.467.374.750.505]
        
        Lymphotoxin-alpha [D12.776.467.374.750.500]
        
        Lymphotoxin-beta [D12.776.467.374.750.515]
        
        OX40 Ligand [D12.776.467.374.750.531]
        
        RANK Ligand [D12.776.467.374.750.562]
        
        TNF-Related Apoptosis-Inducing Ligand [D12.776.467.374.750.625]
        
        Tumor Necrosis Factor Ligand Superfamily Member 13 [D12.776.467.374.750.656]
        
        Tumor Necrosis Factor Ligand Superfamily Member 14 [D12.776.467.374.750.690]
        
        Tumor Necrosis Factor Ligand Superfamily Member 15 [D12.776.467.374.750.710]
        
        Tumor Necrosis Factor-alpha [D12.776.467.374.750.626]

All MeSH Categories
- Chemicals and Drugs Category
  - Biological Factors [D23]
    - Intercellular Signaling Peptides and Proteins [D23.529]
      - Cytokines [D23.529.374]
        
        Monokines [D23.529.374.500]
        
        Interleukin-1 [D23.529.374.500.400] add_circle
        
        Tumor Necrosis Factor-alpha [D23.529.374.500.800]

All MeSH Categories
- Chemicals and Drugs Category
  - Biological Factors [D23]
    - Intercellular Signaling Peptides and Proteins [D23.529]
      - Cytokines [D23.529.374]
        
        Tumor Necrosis Factors [D23.529.374.750]
        
        4-1BB Ligand [D23.529.374.750.065]
        
        B-Cell Activating Factor [D23.529.374.750.061]
        
        CD27 Ligand [D23.529.374.750.030]
        
        CD30 Ligand [D23.529.374.750.092]
        
        CD40 Ligand [D23.529.374.750.124]
        
        Cytokine TWEAK [D23.529.374.750.155]
        
        Ectodysplasins [D23.529.374.750.186]
        
        Fas Ligand Protein [D23.529.374.750.249]
        
        Lymphotoxin alpha1, beta2 Heterotrimer [D23.529.374.750.505]
        
        Lymphotoxin-alpha [D23.529.374.750.500]
        
        Lymphotoxin-beta [D23.529.374.750.515]
        
        OX40 Ligand [D23.529.374.750.531]
        
        RANK Ligand [D23.529.374.750.562]
        
        TNF-Related Apoptosis-Inducing Ligand [D23.529.374.750.625]
        
        Tumor Necrosis Factor Ligand Superfamily Member 13 [D23.529.374.750.656]
        
        Tumor Necrosis Factor Ligand Superfamily Member 14 [D23.529.374.750.690]
        
        Tumor Necrosis Factor Ligand Superfamily Member 15 [D23.529.374.750.710]
        
        Tumor Necrosis Factor-alpha [D23.529.374.750.626]

MeSH 搜索器

Tumor Necrosis Factor-alpha

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