Modulation of Viability, Proliferation, and Stemness by Rosmarinic Acid in Medulloblastoma Cells: Involvement of HDACs and EGFR

Aaronson, S. A. (1991). Growth factors and cancer. Science, 254, 1146–1153. https://doi.org/10.1126/science.1659742

Article  CAS  PubMed  Google Scholar 

Balogun, T. A., Ipinloju, N., Abdullateef, O. T., Moses, S. I., Omoboyowa, D. A., James, A. C., Saibu, O. A., Akinyemi, W. F., & Oni, E. A. (2001). Computational evaluation of bioactive compounds from Colocasia affinis Schott as a novel EGFR inhibitor for cancer treatment. Cancer Informatics, 20, 11769351211049244. https://doi.org/10.1177/11769351211049244

Article  Google Scholar 

Carvalho, B. S., & Irizarry, R. A. (2010). A framework for oligonucleotide microarray preprocessing. Bioinformatics, 26, 2363–2367. https://doi.org/10.1093/bioinformatics/btq431

Article  CAS  PubMed  PubMed Central  Google Scholar 

Casciati, A., Tanori, M., Manczak, R., Saada, S., Tanno, B., Giardullo, P., Porcù, E., Rampazzo, E., Persano, L., Viola, G., Dalmay, C., Lalloué, F., Pothier, A., Merla, C., & Mancuso, M. (2020). Human medulloblastoma cell lines: Investigating on cancer stem cell-like phenotype. Cancers (basel), 12, 226. https://doi.org/10.3390/cancers12010226

Article  CAS  PubMed  Google Scholar 

Cavalli, F. M. G., Remke, M., Rampasek, L., Peacock, J., Shih, D. J. H., Luu, B., Garzia, L., Torchia, J., Nor, C., Morrissy, A. S., Agnihotri, S., Thompson, Y. Y., Kuzan-Fischer, C. M., Farooq, H., Isaev, K., Daniels, C., Cho, B. K., Kim, S. K., Wang, K. C., … Taylor, M. D. (2017). Intertumoral heterogeneity within medulloblastoma subgroups. Cancer Cell, 31(6), 737-754.e6. https://doi.org/10.1016/j.ccell.2017.05.005

Article  CAS  PubMed  PubMed Central  Google Scholar 

Downing, J. R., Wilson, R. K., Zhang, J., Mardis, E. R., Pui, C. H., Ding, L., Ley, T. J., & Evans, W. E. (2012). The pediatric cancer genome project. Nature Genetics, 44, 619–622. https://doi.org/10.1038/ng.2287

Article  CAS  PubMed  PubMed Central  Google Scholar 

Edgar, R., Domrachev, M., & Lash, A. E. (2002). Gene Expression Omnibus: NCBI gene expression and hybridization array data repository. Nucleic Acids Research, 30, 207–210. https://doi.org/10.1093/nar/30.1.207

Article  CAS  PubMed  PubMed Central  Google Scholar 

Ferdousi, F., Sasaki, K., Uchida, Y., Ohkohchi, N., Zheng, Y. W., & Isoda, H. (2019). Exploring the potential role of rosmarinic acid in neuronal differentiation of human amnion epithelial cells by microarray gene expression profiling. Frontiers in Neuroscience, 13, 779. https://doi.org/10.3389/fnins.2019.00779

Article  PubMed  PubMed Central  Google Scholar 

Freire, N. H., Jaeger, M. D. C., de Farias, C. B., Nör, C., Souza, B. K., Gregianin, L., Brunetto, A. T., & Roesler, R. (2023). Targeting the epigenome of cancer stem cells in pediatric nervous system tumors. Molecular and Cellular Biochemistry. https://doi.org/10.1007/s11010-022-04655-2

Article  PubMed  Google Scholar 

Gui, C. Y., Ngo, L., Xu, W. S., Richon, V. M., & Marks, P. A. (2004). Histone deacetylase (HDAC) inhibitor activation of p21WAF1 involves changes in promoter-associated proteins, including HDAC1. Proceedings of the National Academy of Sciences of the United States of America, 101, 1241–1246. https://doi.org/10.1073/pnas.0307708100

Article  CAS  PubMed  PubMed Central  Google Scholar 

Hu, Q., Zhang, L., Wen, J., Wang, S., Li, M., Feng, R., Yang, X., & Li, L. (2010). The EGF receptor-sox2-EGF receptor feedback loop positively regulates the self-renewal of neural precursor cells. Stem Cells, 28, 279–286. https://doi.org/10.1002/stem.246

Article  CAS  PubMed  Google Scholar 

Huang, L., Chen, J., Quan, J., & Xiang, D. (2021). Rosmarinic acid inhibits proliferation and migration, promotes apoptosis and enhances cisplatin sensitivity of melanoma cells through inhibiting ADAM17/EGFR/AKT/GSK3β axis. Bioengineered, 12, 3065–3076. https://doi.org/10.1080/21655979.2021.1941699

Article  CAS  PubMed  PubMed Central  Google Scholar 

Jaeger, M., Ghisleni, E. C., Cardoso, P. S., Siniglaglia, M., Falcon, T., Brunetto, A. T., Brunetto, A. L., de Farias, C. B., Taylor, M. D., Nör, C., Ramaswamy, V., & Roesler, R. (2020). HDAC and MAPK/ERK inhibitors cooperate to reduce viability and stemness in medulloblastoma. Journal of Molecular Neuroscience, 70, 981–992. https://doi.org/10.1007/s12031-020-01505-y

Article  CAS  Google Scholar 

Jaeger, M., Nör, C., de Farias, C. B., Abujamra, A. L., Schwartsmann, G., Brunetto, A. L., & Roesler, R. (2013). Anti-EGFR therapy combined with neuromedin B receptor blockade induces the death of DAOY medulloblastoma cells. Child’s Nervous System, 29, 2145–2150. https://doi.org/10.1007/s00381-013-2290-6

Article  PubMed  Google Scholar 

Jang, J. W., Song, Y., Kim, S. H., Kim, J., & Seo, H. R. (2017). Potential mechanisms of CD133 in cancer stem cells. Life Sciences, 184, 25–29. https://doi.org/10.1016/j.lfs.2017.07.008

Article  CAS  PubMed  Google Scholar 

Jang, Y. G., Hwang, K. A., & Choi, K. C. (2018). Rosmarinic acid, a component of rosemary tea, induced the cell cycle arrest and apoptosis through modulation of HDAC2 expression in prostate cancer cell lines. Nutrients, 10, 1784. https://doi.org/10.3390/nu10111784

Article  CAS  PubMed  PubMed Central  Google Scholar 

Jones, B. L. (2012). The challenge of quality care for family caregivers in pediatric cancer care. Seminars in Oncology Nursing, 28, 213–220. https://doi.org/10.1016/j.soncn.2012.09.003

Article  PubMed  Google Scholar 

Juraschka, K., & Taylor, M. D. (2019). Medulloblastoma in the age of molecular subgroups: A review. Journal of Neurosurgery: Pediatrics, 24, 353–363. https://doi.org/10.3171/2019.5.PEDS18381

Article  PubMed  Google Scholar 

Kauffmann, A., Gentleman, R., & Huber, W. (2009). arrayQualityMetrics—a bioconductor package for quality assessment of microarray data. Bioinformatics, 25, 415–416. https://doi.org/10.1093/bioinformatics/btn647

Article  CAS  PubMed  Google Scholar 

Khan, M. S. S., Iqbal, M. A., Asif, M., Azam, T., Al-Mansoub, M., Haque, R. S. M. A., Basheer, M. K. A., Abdul Majid, A. S., & Abdul Majid, A. M. S. (2019). Anti-GBM potential of Rosmarinic acid and its synthetic derivatives via targeting IL17A mediated angiogenesis pathway. Journal of Angiotherapy, 3, 097–122. https://doi.org/10.25163/angiotherapy.21206512012110519

Article  Google Scholar 

Kim, J., Lo, L., Dormand, E., & Anderson, D. J. (2003). SOX10 maintains multipotency and inhibits neuronal differentiation of neural crest stem cells. Neuron, 38, 17–31. https://doi.org/10.1016/s0896-6273(03)00163-6

Article  CAS  PubMed  Google Scholar 

Kuo, Y. C., & Rajesh, R. (2017). Targeted delivery of rosmarinic acid across the blood-brain barrier for neuronal rescue using polyacrylamide-chitosan-poly(lactide-co-glycolide) nanoparticles with surface cross-reacting material 197 and apolipoprotein E. International Journal of Pharmaceutics, 528(1–2), 228–241. https://doi.org/10.1016/j.ijpharm.2017.05.039

Article  CAS  PubMed  Google Scholar 

Lausen, B., & Schumacher, M. (1992). Maximally selected rank statistics. Biometrics, 48, 73. https://doi.org/10.2307/2532740

Article  Google Scholar 

Li, Y., Dowbenko, D., & Lasky, L. A. (2002). AKT/PKB phosphorylation of p21Cip/WAF1 enhances protein stability of p21Cip/WAF1 and promotes cell survival. Journal of Biological Chemistry, 277, 11352–11361. https://doi.org/10.1074/jbc.M109062200

Article  CAS  PubMed  Google Scholar 

Liu, Y., Xu, X., Tang, H., Pan, Y., Hu, B., & Huang, G. (2021). Rosmarinic acid inhibits cell proliferation, migration, and invasion and induces apoptosis in human glioma cells. International Journal of Molecular Medicine, 47, 67. https://doi.org/10.3892/ijmm.2021.4900

Article  CAS  PubMed  PubMed Central  Google Scholar 

Ma, P., & Schultz, R. M. (2008). Histone deacetylase 1 (HDAC1) regulates histone acetylation, development, and gene expression in preimplantation mouse embryos. Developmental Biology, 319, 110–120. https://doi.org/10.1016/j.ydbio.2008.04.011

Article  CAS  PubMed  Google Scholar 

Messeha, S. S., Zarmouh, N. O., Asiri, A., & Soliman, K. F. A. (2020). Rosmarinic acid-induced apoptosis and cell cycle arrest in triple-negative breast cancer cells. European Journal of Pharmacology, 885, 173419. https://doi.org/10.1016/j.ejphar.2020.173419

Article  CAS  PubMed  PubMed Central  Google Scholar 

Nadeem, M., Imran, M., Aslam Gondal, T., Imran, A., Shahbaz, M., Amir, M. R., Sajid, W. M., Qaisrani, B. T., Atif, M., Hussain, G., Salehi, B., Adrian, A. E., Martorell, M., Sharifi-Rad, J., Cho, C. W., & Martins, N. (2019). Therapeutic potential of rosmarinic acid: A comprehensive review. Applied Sciences, 9, 3139. https://doi.org/10.3390/app9153139

Article  CAS  Google Scholar 

Noguchi-Shinohara, M., Ono, K., Hamaguchi, T., Iwasa, K., Nagai, T., Kobayashi, S., Nakamura, H., & Yamada, M. (2015). Pharmacokinetics, safety and tolerability of Melissa officinalis extract which contained rosmarinic acid in healthy individuals: A randomized controlled Trial. PLoS ONE, 15(5), e0126422. https://doi.org/10.1371/journal.pone.0126422

Article  CAS  Google Scholar 

Noguchi-Shinohara, M., Ono, K., Hamaguchi, T., Nagai, T., Kobayashi, S., Komatsu, J., Samuraki-Yokohama, M., Iwasa, K., Yokoyama, K., Nakamura, H., & Yamada, M. (2020). Safety and efficacy of Melissa officinalis extract containing rosmarinic acid in the prevention of Alzheimer’s disease progression. Science and Reports, 10(1), 18627. https://doi.org/10.1038/s41598-020-73729-2

Article  CAS  Google Scholar 

Nör, C., Sassi, F. A., de Farias, C. B., Schwartsmann, G., Abujamra, A. L., Lenz, G., Brunetto, A. L., & Roesler, R. (2013). The histone deacetylase inhibitor sodium butyrate promotes cell death and differentiation and reduces neurosphere formation in human medulloblastoma cells. Molecular Neurobiology, 48, 533–543. https://doi.org/10.1007/s12035-013-8441-7

Article  CAS 

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