TOF1 and RRM3 reveal a link between gene silencing and the pausing of replication forks

Ahmad K, Henikoff S (2018) No strand left behind. Science 361:1311–1312. https://doi.org/10.1126/science.aav0871

Article  CAS  PubMed  Google Scholar 

Alabert C, Groth A (2012) Chromatin replication and epigenome maintenance. Nat Rev Mol Cell Biol 13:153–167. https://doi.org/10.1038/nrm3288

Article  CAS  PubMed  Google Scholar 

Almouzni G, Cedar H (2016) Maintenance of epigenetic information. Cold Spring Harb Perspect Biol. https://doi.org/10.1101/cshperspect.a019372

Article  PubMed  PubMed Central  Google Scholar 

Azvolinsky A, Dunaway S, Torres JZ et al (2006) The S. cerevisiae Rrm3p DNA helicase moves with the replication fork and affects replication of all yeast chromosomes. Genes Dev 20:3104–3116. https://doi.org/10.1101/gad.1478906

Article  CAS  PubMed  PubMed Central  Google Scholar 

Baretić D, Jenkyn-Bedford M, Aria V et al (2020) Cryo-EM structure of the fork protection complex bound to CMG at a replication fork. Mol Cell 78:926-940.e13. https://doi.org/10.1016/j.molcel.2020.04.012

Article  CAS  PubMed  PubMed Central  Google Scholar 

Bastia D, Srivastava P, Zaman S et al (2016) Phosphorylation of CMG helicase and Tof1 is required for programmed fork arrest. Proc Natl Acad Sci. https://doi.org/10.1073/pnas.1607552113

Article  PubMed  PubMed Central  Google Scholar 

Beranek DT, Heflich RH, Kodell RL, Morris SM, Casciano DA (1983) Correlation between specific DNA-methylation products and mutation induction at the HGPRT locus in Chinese hamster ovary cells. Mutat Res 110:171–180. https://doi.org/10.1016/0027-5107(83)90026-x

Article  CAS  PubMed  Google Scholar 

Brothers M, Rine J (2019) Mutations in the PCNA DNA polymerase clamp of saccharomyces cerevisiae reveal complexities of the cell cycle and ploidy on heterochromatin assembly. Genetics 213:449–463. https://doi.org/10.1534/genetics.119.302452

Article  CAS  PubMed  PubMed Central  Google Scholar 

Deegan TD, Baxter J, Ortiz Bazán MÁ et al (2019) Pif1-family helicases support fork convergence during DNA replication termination in eukaryotes. Mol Cell 74:231-244.e9. https://doi.org/10.1016/j.molcel.2019.01.040

Article  CAS  PubMed  PubMed Central  Google Scholar 

Dodson AE, Rine J (2015) Heritable capture of heterochromatin dynamics in Saccharomyces cerevisiae. Elife 4:e05007–e05007. https://doi.org/10.7554/eLife.05007

Article  PubMed  PubMed Central  Google Scholar 

Gan H, Serra-Cardona A, Hua X et al (2018) The Mcm2-Ctf4-Polα axis facilitates parental histone H3–H4 transfer to lagging strands. Mol Cell 72:140-151.e3. https://doi.org/10.1016/j.molcel.2018.09.001

Article  CAS  PubMed  PubMed Central  Google Scholar 

Gartenberg MR, Smith JS (2016) The Nuts and Bolts of Transcriptionally Silent Chromatin in Saccharomyces cerevisiae. Genetics 203:1563–1599. https://doi.org/10.1534/genetics.112.145243

Article  CAS  PubMed  PubMed Central  Google Scholar 

Gerard A, Koundrioukoff S, Ramillon V et al (2006) The replication kinase Cdc7-Dbf4 promotes the interaction of the p150 subunit of chromatin assembly factor 1 with proliferating cell nuclear antigen. EMBO Rep 7:817–823. https://doi.org/10.1038/sj.embor.7400750

Article  CAS  PubMed  PubMed Central  Google Scholar 

Gottschling DE, Aparicio OM, Billington BL, Zakian VA (1990) Position effect at S. cerevisiae telomeres: reversible repression of Pol II transcription. Cell 63:751–762

Article  CAS  PubMed  Google Scholar 

Groth A, Corpet A, Cook AJ et al (2007) Regulation of replication fork progression through histone supply and demand. Science 318:1928–1931. https://doi.org/10.1126/science.1148992

Article  CAS  PubMed  Google Scholar 

Hastie T, Tibshirani R, Friedman J (2009) The elements of statistical learning. Springer Ser Statist. https://doi.org/10.1007/978-0-387-84858-7

Article  Google Scholar 

Ivessa AS, Lenzmeier BA, Bessler JB et al (2003) The Saccharomyces cerevisiae helicase Rrm3p facilitates replication past nonhistone protein-DNA complexes. Mol Cell 12:1525–1536

Article  CAS  PubMed  Google Scholar 

Janke R, King GA, Kupiec M, Rine J (2018) Pivotal roles of PCNA loading and unloading in heterochromatin function. Proc Natl Acad Sci U S A 115:E2030–E2039. https://doi.org/10.1073/pnas.1721573115

Article  CAS  PubMed  PubMed Central  Google Scholar 

Jeffery DC, Wyse BA, Rehman MA et al (2013) Analysis of epigenetic stability and conversions in Saccharomyces cerevisiae reveals a novel role of CAF-I in position-effect variegation. Nucleic Acids Res 41:8475–8488. https://doi.org/10.1093/nar/gkt623

Article  CAS  PubMed  PubMed Central  Google Scholar 

Jeffery DC, Kakusho N, You Z et al (2015) CDC28 phosphorylates Cac1p and regulates the association of chromatin assembly factor I with chromatin. Cell Cycle 14:74–85. https://doi.org/10.4161/15384101.2014.973745

Article  CAS  PubMed  PubMed Central  Google Scholar 

Kurat CF, Yeeles JTP, Patel H, Early A, Diffley JFX (2017) Chromatin controls DNA replication origin selection, lagging-strand synthesis, and replication fork rates. Mol Cell 65:117–130. https://doi.org/10.1016/j.molcel.2016.11.016

Article  CAS  PubMed  PubMed Central  Google Scholar 

Makovets S, Herskowitz I, Blackburn EH (2004) Anatomy and dynamics of DNA replication fork movement in yeast telomeric regions. Mol Cell Biol 24:4019–4031

Article  CAS  PubMed  PubMed Central  Google Scholar 

Mano Y, Kobayashi TJ, Nakayama J et al (2013) Single cell visualization of yeast gene expression shows correlation of epigenetic switching between multiple heterochromatic regions through multiple generations. PLoS Biol 11:e1001601–e1001601. https://doi.org/10.1371/journal.pbio.1001601

Article  CAS  PubMed  PubMed Central  Google Scholar 

Mohanty BK, Bairwa NK, Bastia D (2006) The Tof1p-Csm3p protein complex counteracts the Rrm3p helicase to control replication termination of Saccharomyces cerevisiae. Proc Natl Acad Sci USA 103:897–902. https://doi.org/10.1073/pnas.0506540103

Article  CAS  PubMed  PubMed Central  Google Scholar 

Paeschke K, Capra JA, Zakian VA (2011) DNA replication through G-quadruplex motifs is promoted by the Saccharomyces cerevisiae Pif1 DNA helicase. Cell 145:678–691. https://doi.org/10.1016/j.cell.2011.04.015

Article  CAS  PubMed  PubMed Central  Google Scholar 

Park H, Sternglanz R (1999) Identification and characterization of the genes for two topoisomerase I-interacting proteins from Saccharomyces cerevisiae. Yeast 15:35–41. https://doi.org/10.1002/(SICI)1097-0061(19990115)15:1%3c35::AID-YEA340%3e3.0.CO;2-R

Article  CAS  PubMed  Google Scholar 

Petryk N, Dalby M, Wenger A et al (2018) MCM2 promotes symmetric inheritance of modified histones during DNA replication. Science 361:1389–1392. https://doi.org/10.1126/science.aau0294

Article  CAS  PubMed  Google Scholar 

Pohl TJ, Zakian VA (2019) Pif1 family DNA helicases: a helpmate to RNase H? DNA Repair 84:102633. https://doi.org/10.1016/j.dnarep.2019.06.004

Article  CAS  PubMed  PubMed Central  Google Scholar 

Rossmann MP, Luo W, Tsaponina O et al (2011) A common telomeric gene silencing assay is affected by nucleotide metabolism. Mol Cell. https://doi.org/10.1016/j.molcel.2011.03.007

Article  PubMed  PubMed Central  Google Scholar 

Rowlands H, Dhavarasa P, Cheng A, Yankulov K (2017) Forks on the run: can the stalling of DNA replication promote epigenetic changes? Front Genet 8:86. https://doi.org/10.3389/fgene.2017.00086

Article  CAS  PubMed  PubMed Central  Google Scholar 

Rowlands H, Shaban K, Cheng A et al (2019a) Dysfunctional CAF-I reveals its role in cell cycle progression and differential regulation of gene silencing. Cell Cycle 18:3223–3236. https://doi.org/10.1080/15384101.2019.1673100

Article  CAS  PubMed  PubMed Central  Google Scholar 

Rowlands H, Shaban K, Foster B et al (2019b) Histone chaperones and the Rrm3p helicase regulate flocculation in S. cerevisiae. Epigenet Chromatin 12:56. https://doi.org/10.1186/s13072-019-0303-8

Article  CAS  Google Scholar 

Rusche LN, Kirchmaier AL, Rine J (2003) The establishment, inheritance, and function of silenced chromatin in Saccharomyces cerevisiae. Annu Rev Biochem 72:481–516. https://doi.org/10.1146/annurev.biochem.72.121801.161547

Article  CAS  PubMed  Google Scholar 

Safaric B, Chacin E, Scherr MJ et al (2022) The fork protection complex recruits FACT to reorganize nucleosomes during replication. Nucleic Acids Res 50:1317–1334. https://doi.org/10.1093/nar/gkac005

Article  CAS  PubMed 

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