Exercise and epigenetic ages in older adults with myeloid malignancies

SEER Cancer Statistics Factsheets: Acute Myeloid Leukemia. National Cancer Institute. Bethesda, MD, http://seer.cancer.gov/statfacts/html/amyl.html.

Ma X, Does M, Raza A, Mayne ST. Myelodysplastic syndromes: incidence and survival in the United States. Cancer. 2007;109(8):1536–42.

Article  PubMed  Google Scholar 

Arber DA, Orazi A, Hasserjian R, Thiele J, Borowitz MJ, Le Beau MM, et al. The 2016 revision to the World Health Organization classification of myeloid neoplasms and acute leukemia. Blood. 2016;127(20):2391–405.

Article  CAS  PubMed  Google Scholar 

Klepin HD, Geiger AM, Tooze JA, Kritchevsky SB, Williamson JD, Pardee TS, et al. Geriatric assessment predicts survival for older adults receiving induction chemotherapy for acute myelogenous leukemia. Blood. 2013;121(21):4287–94.

Article  CAS  PubMed  PubMed Central  Google Scholar 

Klepin HD, Tooze JA, Pardee TS, Ellis LR, Berenzon D, Mihalko SL, et al. Effect of intensive chemotherapy on physical, cognitive, and emotional health of older adults with acute myeloid leukemia. J Am Geriatr Soc. 2016;64(10):1988–95.

Article  PubMed  PubMed Central  Google Scholar 

Alibhai SM, Leach M, Kermalli H, Gupta V, Kowgier ME, Tomlinson GA, et al. The impact of acute myeloid leukemia and its treatment on quality of life and functional status in older adults. Crit Rev Oncol Hematol. 2007;64(1):19–30.

Article  PubMed  Google Scholar 

Saad M, Loh KP, Tooze JA, Pardee TS, Ellis LR, Powell B, et al. Geriatric assessment and survival among older adults receiving post-remission therapy for acute myeloid leukemia. Blood. 2020. https://doi.org/10.1182/blood.2020005498.

Article  PubMed  PubMed Central  Google Scholar 

Loh KP, Tooze JA, Nicklas BJ, Kritchevsky SB, Williamson JD, Ellis LR, et al. Inflammatory biomarkers, geriatric assessment, and treatment outcomes in acute myeloid leukemia. J Geriatr Oncol. 2020;11(3):410–6.

Article  PubMed  Google Scholar 

Loh KP, Ramsdale E, Culakova E, Mendler JH, Liesveld JL, O’Dwyer KM, et al. Novel mHealth app to deliver geriatric assessment-driven interventions for older adults with cancer: pilot feasibility and usability study. JMIR Cancer. 2018;4(2):e10296.

Article  PubMed  PubMed Central  Google Scholar 

Loh KP, Duberstein P, Zittel J, Lei L, Culakova E, Xu H, et al. Relationships of self-perceived age with geriatric assessment domains in older adults with cancer. J Geriatr Oncol. 2020;11(6):1006–10.

Article  PubMed  Google Scholar 

Tinsley SM, Sutton SK, Thapa R, Lancet J, McMillan SC. Treatment choices: a quality of life comparison in acute myeloid leukemia and high-risk myelodysplastic syndrome. Clin Lymphoma Myeloma Leuk. 2017;17s:S75–9.

Article  PubMed  Google Scholar 

Wyatt G, Sikorskii A, Tesnjak I, Victorson D, Srkalovic G. Chemotherapy interruptions in relation to symptom severity in advanced breast cancer. Support Care Cancer. 2015;23(11):3183–91.

Article  PubMed  PubMed Central  Google Scholar 

Brown JC, Harhay MO, Harhay MN. Physical function as a prognostic biomarker among cancer survivors. Br J Cancer. 2015;112(1):194–8.

Article  CAS  PubMed  Google Scholar 

Hurria A, Togawa K, Mohile SG, Owusu C, Klepin HD, Gross CP, et al. Predicting chemotherapy toxicity in older adults with cancer: a prospective multicenter study. J Clin Oncol. 2011;29(25):3457–65.

Article  CAS  PubMed  PubMed Central  Google Scholar 

Jylhava J, Pedersen NL, Hagg S. Biological age predictors. EBioMedicine. 2017;21:29–36.

Article  PubMed  PubMed Central  Google Scholar 

Jia L, Zhang W, Chen X. Common methods of biological age estimation. Clin Interv Aging. 2017;12:759–72.

Article  PubMed  PubMed Central  Google Scholar 

Field AE, Robertson NA, Wang T, Havas A, Ideker T, Adams PD. DNA methylation clocks in aging: categories, causes, and consequences. Mol Cell. 2018;71(6):882–95.

Article  CAS  PubMed  PubMed Central  Google Scholar 

Jin B, Li Y, Robertson KD. DNA methylation: superior or subordinate in the epigenetic hierarchy? Genes Cancer. 2011;2(6):607–17.

Article  CAS  PubMed  PubMed Central  Google Scholar 

Kim M, Costello J. DNA methylation: an epigenetic mark of cellular memory. Exp Mol Med. 2017;49(4):e322.

Article  CAS  PubMed  PubMed Central  Google Scholar 

Lu AT, Quach A, Wilson JG, Reiner AP, Aviv A, Raj K, et al. DNA methylation GrimAge strongly predicts lifespan and healthspan. Aging (Albany NY). 2019;11(2):303–27.

Article  CAS  PubMed  Google Scholar 

Horvath S. DNA methylation age of human tissues and cell types. Genome Biol. 2013;14(10):R115.

Article  PubMed  PubMed Central  Google Scholar 

Gale CR, Marioni RE, Cukic I, Chastin SF, Dall PM, Dontje ML, et al. The epigenetic clock and objectively measured sedentary and walking behavior in older adults: the Lothian Birth Cohort 1936. Clin Epigenetics. 2018;10:4.

Article  PubMed  PubMed Central  Google Scholar 

Levine ME, Lu AT, Quach A, Chen BH, Assimes TL, Bandinelli S, et al. An epigenetic biomarker of aging for lifespan and healthspan. Aging (Albany NY). 2018;10(4):573–91.

Article  PubMed  Google Scholar 

Hannum G, Guinney J, Zhao L, Zhang L, Hughes G, Sadda S, et al. Genome-wide methylation profiles reveal quantitative views of human aging rates. Mol Cell. 2013;49(2):359–67.

Article  CAS  PubMed  Google Scholar 

Chen BH, Marioni RE, Colicino E, Peters MJ, Ward-Caviness CK, Tsai PC, et al. DNA methylation-based measures of biological age: meta-analysis predicting time to death. Aging. 2016;8(9):1844–65.

Article  CAS  PubMed  PubMed Central  Google Scholar 

Xiao FH, Wang HT, Kong QP. Dynamic DNA methylation during aging: A “Prophet” of age-related outcomes. Front Genet. 2019;10:107.

Article  CAS  PubMed  PubMed Central  Google Scholar 

Maddock J, Castillo-Fernandez J, Wong A, Cooper R, Richards M, Ong KK, et al. DNA Methylation age and physical and cognitive aging. J Gerontol A Biol Sci Med Sci. 2020;75(3):504–11.

CAS  PubMed  Google Scholar 

Beydoun MA, Shaked D, Tajuddin SM, Weiss J, Evans MK, Zonderman AB. Accelerated epigenetic age and cognitive decline among urban-dwelling adults. Neurology. 2020;94(6):e613–25.

Article  PubMed  PubMed Central  Google Scholar 

Castle JR, Lin N, Liu J, Storniolo AMV, Shendre A, Hou L, et al. Estimating breast tissue-specific DNA methylation age using next-generation sequencing data. Clin Epigenetics. 2020;12(1):45.

Article  CAS  PubMed  PubMed Central  Google Scholar 

Sehl ME, Carroll JE, Horvath S, Bower JE. The acute effects of adjuvant radiation and chemotherapy on peripheral blood epigenetic age in early stage breast cancer patients. NPJ Breast Cancer. 2020;6:23.

Article  CAS  PubMed  PubMed Central  Google Scholar 

Scuric Z, Carroll JE, Bower JE, Ramos-Perlberg S, Petersen L, Esquivel S, et al. Biomarkers of aging associated with past treatments in breast cancer survivors. NPJ breast cancer. 2017;3:50.

Article  PubMed  PubMed Central  Google Scholar 

Belsky DW, Caspi A, Corcoran DL, Sugden K, Poulton R, Arseneault L, et al. DunedinPACE, a DNA methylation biomarker of the pace of aging. Elife. 2022. https://doi.org/10.7554/eLife.73420.

Article  PubMed  PubMed Central  Google Scholar 

Levine ME. Assessment of epigenetic clocks as biomarkers of aging in basic and population research. J Gerontol A Biol Sci Med Sci. 2020;75(3):463–5.

Article  PubMed  PubMed Central  Google Scholar 

Waziry R, Corcoran DL, Huffman KM, Kobor MS, Kothari M, Kraus VB, et al. Effect of Long-Term Caloric Restriction on DNA Methylation Measures of Biological Aging in Healthy Adults: CALERIE™ Trial Analysis. medRxiv. 2021;2021.09.21.21263912.

Schuler MK, Hentschel L, Göbel J, Balaian E, Hornemann B, Hoffmann J, et al. Effects of a home-based exercise program on physical capacity and fatigue in patients with low to intermediate risk myelodysplastic syndrome-a pilot study. Leuk Res. 2016;47:128–35.

Article  PubMed  Google Scholar 

Klepin HD, Danhauer SC, Tooze JA, Stott K, Daley K, Vishnevsky T, et al. Exercise for older adult inpatients with acute myelogenous leukemia: a pilot study. J Geriatr Oncol. 2011;2(1):11–7.

Article  PubMed  PubMed Central  Google Scholar 

Schaffer K, Panneerselvam N, Loh KP, Herrmann R, Kleckner IR, Dunne RF, et al. Systematic review of randomized controlled trials of exercise interventions using digital activity trackers in patients with cancer. J Nat Compr Canc Netw JNCCN. 2019;17(1):57–63.

Article  CAS  Google Scholar 

Valenzuela T, Okubo Y, Woodbury A, Lord SR, Delbaere K. Adherence to technology-based exercise programs in older adults: a systematic review. J Geriatr Phys Ther. 2018;41(1):49–61.

留言 (0)

沒有登入
gif