Cutler DJ. Theory of the mean absorption time, an adjunct to conventional bioavailability studies. J Pharm Pharmacol. 1978;30(8):476–8. https://doi.org/10.1111/j.2042-7158.1978.tb13296.x.
Article CAS PubMed Google Scholar
Weiss M. The relevance of residence time theory to pharmacokinetics. Eur J Clin Pharmacol. 1992;43(6):571–9. https://doi.org/10.1007/BF02284953.
Article CAS PubMed Google Scholar
Weiss M. Generalizations in linear pharmacokinetics using properties of certain classes of residence time distributions. II. Log-concave concentration-time curves following oral administration. J Pharmacokinet Biopharm. 1987;15(1):57–74. https://doi.org/10.1007/BF01062939.
Article CAS PubMed Google Scholar
May K, Giessmann T, Wegner D, Oertel R, Modess C, Oswald S, et al. Oral absorption of propiverine solution and of the immediate and extended release dosage forms: influence of regioselective intestinal elimination. Eur J Clin Pharmacol. 2008;64(11):1085–92. https://doi.org/10.1007/s00228-008-0528-0.
Article CAS PubMed Google Scholar
Weiss M, Sermsappasuk P, Siegmund W. Modeling the heterogeneous intestinal absorption of propiverine extended-release. Eur J Pharm Sci. 2015;76:133–7. https://doi.org/10.1016/j.ejps.2015.05.010.
Article CAS PubMed Google Scholar
Abebe BT, Weiss M, Modess C, Roustom T, Tadken T, Wegner D, et al. Effects of the P-glycoprotein inhibitor clarithromycin on the pharmacokinetics of intravenous and oral trospium chloride: a 4-way crossover drug-drug interaction study in healthy subjects. J Clin Pharmacol. 2019. https://doi.org/10.1002/jcph.1421.
Abebe BT, Weiss M, Modess C, Tadken T, Wegner D, Meyer MJ, et al. Pharmacokinetic drug-drug interactions between trospium chloride and ranitidine substrates of organic cation transporters in healthy human subjects. J Clin Pharmacol. 2020;60(3):312–23. https://doi.org/10.1002/jcph.1523.
Article CAS PubMed Google Scholar
Tadken T, Weiss M, Modess C, Wegner D, Roustom T, Neumeister C, et al. Trospium chloride is absorbed from two intestinal “absorption windows” with different permeability in healthy subjects. Int J Pharm. 2016;515(1–2):367-73 S0378-5173(16)30973-5. https://doi.org/10.1016/j.ijpharm.2016.10.030.
Article CAS PubMed Google Scholar
Weiss M, Siegmund W. Pharmacokinetic modeling of ketamine enantiomers and their metabolites after administration of prolonged-release ketamine with emphasis on 2,6-hydroxynorketamines. Clin Pharmacol Drug Dev. 2022;11(2):194–206. https://doi.org/10.1002/cpdd.993.
Article CAS PubMed Google Scholar
Dahan A, Miller JM, Amidon GL. Prediction of solubility and permeability class membership: provisional BCS classification of the world’s top oral drugs. AAPS J. 2009;11(4):740–6. https://doi.org/10.1208/s12248-009-9144-x.
Article CAS PubMed PubMed Central Google Scholar
Weiss M, D’Argenio DZ, Siegmund W. Analysis of complex absorption after multiple dosing: application to the interaction between the P-glycoprotein substrate talinolol and rifampicin. Pharm Res. 2022;39(12):3293–300. https://doi.org/10.1007/s11095-022-03397-6.
Article CAS PubMed PubMed Central Google Scholar
Oswald S, Terhaag B, Siegmund W. In vivo probes of drug transport: commonly used probe drugs to assess function of intestinal P-glycoprotein (ABCB1) in humans. Handb Exp Pharmacol. 2011;201:403–47. https://doi.org/10.1007/978-3-642-14541-4_11.
Csajka C, Drover D, Verotta D. The use of a sum of inverse Gaussian functions to describe the absorption profile of drugs exhibiting complex absorption. Pharm Res. 2005;22(8):1227–35. https://doi.org/10.1007/s11095-005-5266-8.
Article CAS PubMed Google Scholar
Weiss M. A novel extravascular input function for the assessment of drug absorption in bioavailability studies. Pharm Res. 1996;13(10):1547–53.
Article CAS PubMed Google Scholar
Weiss M. Empirical models for fitting of oral concentration time curves with and without an intravenous reference. J Pharmacokinet Pharmacodyn. 2017;44(3):193–201. https://doi.org/10.1007/s10928-017-9507-3;10.1007/s10928-017-9507-3.
Riegelman S, Collier P. The application of statistical moment theory to the evaluation of in vivo dissolution time and absorption time. J Pharmacokinet Biopharm. 1980;8(5):509–34. https://doi.org/10.1007/BF01059549.
Article CAS PubMed Google Scholar
D’Argenio D, Schumitzky A, Wang X. User’s guide: pharmacokinetic/pharmacodynamic systems analysis software. Los Angeles, CA: Biomedical Simulations Resource; 2009.
Weiss M. Relationship between dissolution rate in vitro and absorption rate in vivo of ketamine prolonged-release tablets. Eur J Drug Metab Pharmacokinet. 2023. https://doi.org/10.1007/s13318-022-00812-6.
Article PubMed PubMed Central Google Scholar
Bergstrand M, Soderlind E, Weitschies W, Karlsson MO. Mechanistic modeling of a magnetic marker monitoring study linking gastrointestinal tablet transit, in vivo drug release, and pharmacokinetics. Clin Pharmacol Ther. 2009;86(1):77–83. https://doi.org/10.1038/clpt.2009.43.
Article CAS PubMed Google Scholar
Cora LA, Romeiro FG, Americo MF, Oliveira RB, Baffa O, Stelzer M, et al. Gastrointestinal transit and disintegration of enteric coated magnetic tablets assessed by ac biosusceptometry. Eur J Pharm Sci. 2006;27(1):1–8. https://doi.org/10.1016/j.ejps.2005.08.009.
Article CAS PubMed Google Scholar
Kolbow J, Modess C, Wegner D, Oswald S, Maritz MA, Rey H, et al. Extended-release but not immediate-release and subcutaneous methylnaltrexone antagonizes the loperamide-induced delay of whole-gut transit time in healthy subjects. J Clin Pharmacol. 2015. https://doi.org/10.1002/jcph.624.
Abuhelwa AY, Foster DJR, Upton RN. A quantitative review and meta-models of the variability and factors affecting oral drug absorption-part I: gastrointestinal pH. AAPS J. 2016;18(5):1309–21. https://doi.org/10.1208/s12248-016-9952-8.
Article CAS PubMed Google Scholar
Keller F, Kunzendorf U, Walz G, Haller H, Offermann G. Saturable first-pass kinetics of propranolol. J Clin Pharmacol. 1989;29(3):240–5. https://doi.org/10.1002/j.1552-4604.1989.tb03320.x.
Article CAS PubMed Google Scholar
Mistry B, Leslie JL, Eddington ND. Influence of input rate on the stereospecific and nonstereospecific first pass metabolism and pharmacokinetics of metoprolol extended release formulations. Chirality. 2002;14(4):297–304. https://doi.org/10.1002/chir.10045.
Article CAS PubMed Google Scholar
Wagner JG. Propranolol: pooled Michaelis-Menten parameters and the effect of input rate on bioavailability. Clin Pharmacol Ther. 1985;37(5):481–7. https://doi.org/10.1038/clpt.1985.76.
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