Correspondence to: Gan-Xin Yan, MD, PhD, Lankenau Institute for Medical Research, Wynnewood, PA 19096, Email

E-mail Address: [email protected]

https://orcid.org/0000-0002-3118-5680

Zhengzhou University People’s Hospital and Central China Fuwai Hospital, Zhengzhou, China (D.Q., C.G., G.-X.Y.).

Lankenau Institute for Medical Research, Wynnewood, PA (D.Q., X.-Q.Q., Y.G., J.W., W.Z., G.-X.Y.).

Sidney Kimmel Medical College at Thomas Jefferson University, Philadelphia, PA (G.-X.Y.).