Sui Z, Zhang X, Li H, Xu D, Li G (2021) Magnetic resonance imaging evaluation of brain glioma before postoperative radiotherapy. Clin Transl Oncol 23:820–826

Article  CAS  Google Scholar 

Clarke RH, Moosa S, Anzivino M, Wang Y, Floyd DH et al (2014) Sustained radiosensitization of hypoxic glioma cells after oxygen pretreatment in an animal model of glioblastoma and in vitro models of tumor hypoxia. PLoS ONE 9:e111199

Article  Google Scholar 

Toyonaga T, Hirata K, Shiga T, Nagara T (2017) Players of “hypoxia orchestra” - what is the role of FMISO? Eur J Nucl Med Mol Imaging 44:1679–1681

Article  Google Scholar 

Mudassar F, Shen H, O’Neill G, Hau E (2020) Targeting tumor hypoxia and mitochondrial metabolism with anti-parasitic drugs to improve radiation response in high-grade gliomas. J Exp Clin Cancer Res 39:208

Article  CAS  Google Scholar 

Hua L, Wang Z, Zhao L, Mao H, Wang G et al (2018) Hypoxia-responsive lipid-poly-(hypoxic radiosensitized polyprodrug) nanoparticles for glioma chemo- and radiotherapy. Theranostics 8:5088–5105

Article  CAS  Google Scholar 

Horsman MR, Mortensen LS, Petersen JB, Busk M, Overgaard J (2012) Imaging hypoxia to improve radiotherapy outcome. Nat Rev Clin Oncol 9:674–687

Article  CAS  Google Scholar 

Qi R, Jin W, Wang J, Yi Q, Yu M et al (2014) Oleanolic acid enhances the radiosensitivity of tumor cells under mimetic hypoxia through the reduction in intracellular GSH content and HIF-1alpha expression. Oncol Rep 31:2399–2406

Article  CAS  Google Scholar 

Gao D, Tang S, Tong Q (2012) Oleanolic acid liposomes with polyethylene glycol modification: promising antitumor drug delivery. Int J Nanomed 7:3517–3526

Article  CAS  Google Scholar 

Fahrni G, Karakatsanis NA, Di Domenicantonio G, Garibotto V, Zaidi H (2019) Does whole-body Patlak (18)F-FDG PET imaging improve lesion detectability in clinical oncology? Eur Radiol 29:4812–4821

Article  Google Scholar 

Cheebsumon P, Velasquez LM, Hoekstra CJ, Hayes W, Kloet RW et al (2011) Measuring response to therapy using FDG PET: semi-quantitative and full kinetic analysis. Eur J Nucl Med Mol Imaging 38:832–842

Article  CAS  Google Scholar 

Bartlett RM, Beattie BJ, Naryanan M, Georgi JC, Chen Q et al (2012) Image-guided PO2 probe measurements correlated with parametric images derived from 18F-fluoromisonidazole small-animal PET data in rats. J Nucl Med 53:1608–1615

Article  CAS  Google Scholar 

van der Weerdt AP, Klein LJ, Boellaard R, Visser CA, Visser FC et al (2001) Image-derived input functions for determination of MRGlu in cardiac (18)F-FDG PET scans. J Nucl Med 42:1622–1629

Google Scholar 

Freedman NM, Sundaram SK, Kurdziel K, Carrasquillo JA, Whatley M et al (2003) Comparison of SUV and Patlak slope for monitoring of cancer therapy using serial PET scans. Eur J Nucl Med Mol Imaging 30:46–53

Article  Google Scholar 

Ali MY, Oliva CR, Noman A, Allen BG, Goswami PC et al (2020) Radioresistance in glioblastoma and the development of radiosensitizers. Cancers (Basel) 12:2511

Article  CAS  Google Scholar 

Abdo RA, Lamare F, Fernandez P, Bentourkia M (2019) Analysis of hypoxia in human glioblastoma tumors with dynamic 18F-FMISO PET imaging. Australas Phys Eng Sci Med 42:981–993

Article  Google Scholar 

Chedeville AL, Madureira PA (2021) The role of hypoxia in glioblastoma radiotherapy resistance. Cancers (Basel) 13:542

Article  CAS  Google Scholar 

Gong L, Zhang Y, Liu C, Zhang M, Han S (2021) Application of radiosensitizers in cancer radiotherapy. Int J Nanomedicine 16:1083–1102

Article  Google Scholar 

Wang J, Yu M, Xiao L, Xu S, Yi Q et al (2013) Radiosensitizing effect of oleanolic acid on tumor cells through the inhibition of GSH synthesis in vitro. Oncol Rep 30:917–924

Article  CAS  Google Scholar 

Rahmim A, Lodge MA, Karakatsanis NA, Panin VY, Zhou Y et al (2019) Dynamic whole-body PET imaging: principles, potentials and applications. Eur J Nucl Med Mol Imaging 46:501–518

Article  Google Scholar 

van Sluis J, Yaqub M, Brouwers AH, Dierckx R, Noordzij W et al (2021) Use of population input functions for reduced scan duration whole-body Patlak (18)F-FDG PET imaging. EJNMMI Phys 8:11

Article  Google Scholar 

Karakatsanis NA, Zhou Y, Lodge MA, Casey ME, Wahl RL et al (2015) Generalized whole-body Patlak parametric imaging for enhanced quantification in clinical PET. Phys Med Bio 60:8643–8673

Article  CAS  Google Scholar 

Patlak CS, Blasberg RG (1983) Graphical evaluation of blood-to-brain transfer constants from multiple-time uptake data. J Cereb Blood Flow Metab 3:1–7

Article  CAS  Google Scholar 

Masaki Y, Shimizu Y, Yoshioka T, Nishijima KI, Zhao S et al (2017) FMISO accumulation in tumor is dependent on glutathione conjugation capacity in addition to hypoxic state. Ann Nucl Med 31:596–604

Article  CAS  Google Scholar 

Toyonaga T, Hirata K, Yamaguchi S, Hatanaka KC, Yuzawa S et al (2016) (18)F-fluoromisonidazole positron emission tomography can predict pathological necrosis of brain tumors. Eur J Nucl Med Mol Imaging 43:1469–1476

Article  CAS  Google Scholar 

Toyonaga T, Yamaguchi S, Hirata K, Kobayashi K, Manabe O et al (2017) Hypoxic glucose metabolism in glioblastoma as a potential prognostic factor. Eur J Nucl Med Mol Imaging 44:611–619

Article  CAS  Google Scholar 

Eschmann SM, Paulsen F, Reimold M, Dittmann H, Welz S et al (2005) Prognostic impact of hypoxia imaging with 18F-misonidazole PET in non-small cell lung cancer and head and neck cancer before radiotherapy. J Nucl Med 46:253–260

Google Scholar 

Gagel B, Piroth M, Pinkawa M, Reinartz P, Zimny M et al (2007) pO polarography, contrast enhanced color duplex sonography (CDS), [18F] fluoromisonidazole and [18F] fluorodeoxyglucose positron emission tomography: validated methods for the evaluation of therapy-relevant tumor oxygenation or only bricks in the puzzle of tumor hypoxia? BMC Cancer 7:113

Article  Google Scholar 

Jiang BH, Semenza GL, Bauer C, Marti HH (1996) Hypoxia-inducible factor 1 levels vary exponentially over a physiologically relevant range of O2 tension. Am J Physiol-Cell Ph 271:C1172–C1180

Article  CAS  Google Scholar 

Sun J, Chen C, Wei W, Zheng H, Yuan J et al (2015) Associations and indications of Ki67 expression with clinicopathological parameters and molecular subtypes in invasive breast cancer: a population-based study. Oncol Lett 10:1741–1748

Article  CAS  Google Scholar 

Takahashi M, Nojima H, Kuboki S, Horikoshi T, Yokota T et al (2020) Comparing prognostic factors of Glut-1 expression and maximum standardized uptake value by FDG-PET in patients with resectable pancreatic cancer. Pancreatology 20:1205–1212

Article  CAS  Google Scholar