1. Smyth, EC, Nilsson, M, Grabsch, HI, et al. Gastric cancer. Lancet. 2020;396(10251):635-648.
Google Scholar | Crossref | Medline2. Choi, SJ, Jung, SW, Huh, S, Chung, YS, Cho, H, Kang, H. Alteration of DNA methylation in gastric cancer with chemotherapy. J Microbiol Biotechnol. 2017;27(8):1367-1378.
Google Scholar | Crossref | Medline3. Lippert, TH, Ruoff, HJ, Volm, M. Intrinsic and acquired drug resistance in malignant tumors. The main reason for therapeutic failure. Arzneimittelforschung. 2008;58(6):261-264.
Google Scholar | Medline | ISI4. Hamilton, B, Frankel, W, Kerrebrock, A, et al. Disruption of the nuclear hormone receptor RORα in staggerer mice. Nature. 1996;379(6567):736-739.
Google Scholar | Crossref | Medline5. Cho, H, Zhao, X, Hatori, M, et al. Regulation of circadian behavior and metabolism by REV-ERBα and REV-ERBβ. Nature. 2012;485(7396):123-127.
Google Scholar | Crossref | Medline | ISI6. Lee, JM, Kim, IS, Kim, H, et al. RORalpha attenuates Wnt/beta-catenin signaling by PKCalpha-dependent phosphorylation in colon cancer. Mol Cell. 2010;37(2):183-195.
Google Scholar | Crossref | Medline7. Du, J, Xu, R. RORalpha, a potential tumor suppressor and therapeutic target of breast cancer. Int J Mol Sci. 2012;13(1):15755-15766.
Google Scholar | Crossref | Medline8. Xiong, G, Wang, C, Evers, BM, Zhou, BP, Xu, R. RORα suppresses breast tumor invasion by inducing SEMA3F expression. Cancer Res. 2012;72(7):1728-1739.
Google Scholar | Crossref | Medline9. Rakhshan, A, Omrani, MD, Noroozi, R, Taheri, M, Ghafouri-Fard, S. Retinoic acid related orphan receptor A (RORA) gene variants and risk of bladder cancer. Gene Rep. 2019;14(1):22-24.
Google Scholar | Crossref10. Wang, XS, Wang, N, Wei, X, Yu, HY, Wang, ZG. REV-ERBα reduction is associated with clinicopathological features and prognosis in human gastric cancer. Oncol Lett. 2018;16(2):1499-1506.
Google Scholar | Medline11. Wang, ZG, Xiong, FY, Wang, XS, et al. Nuclear receptor retinoid-related orphan receptor alpha promotes apoptosis but is reduced in human gastric cancer. Oncotarget. 2017;8(7):11105-11113.
Google Scholar | Crossref | Medline12. Yuan, SQ, Nie, RC, Chen, YM, et al. Glasgow prognostic score is superior to ECOG PS as a prognostic factor in patients with gastric cancer with peritoneal seeding. Oncol Lett. 2018;15(4):4193-4200.
Google Scholar | Medline13. Livak, KJ, Schmittgen, TD. Analysis of relative gene expression data using real-time quantitative PCR and the 2-ΔΔCT method. Methods. 2001;25(4):402-408.
Google Scholar | Crossref | Medline | ISI14. Garcia, J, Rosen, G, Mahowald, M. Circadian rhythms and circadian rhythm disorders in children and adolescents. Semin Pediatr Neurol. 2001;8(4):229-240.
Google Scholar | Crossref | Medline15. Chen, RY, Fan, YM, Zhang, Q, et al. Estradiol inhibits Th17 cell differentiation through inhibition of RORγT transcription by recruiting the ERα/REA complex to estrogen response elements of the RORγT promoter. J Immunol. 2015;194(8):4019-4028.
Google Scholar | Crossref | Medline16. Fu, RD, Qiu, CH, Chen, HA, Zhang, ZG, Lu, MQ. Retinoic acid receptor-related receptor alpha (RORalpha) is a prognostic marker for hepatocellular carcinoma. Tumor Biol. 2014;358(8):7603-7610.
Google Scholar | Crossref17. Yang, G, Wright, CJ, Hinson, MD, et al. Inflammation modulate REV-ERBα signaling in the neonatal lung and affect circadian rhythmicity. Antioxid Redox Signal. 2014;21(1):17-32.
Google Scholar | Crossref | Medline18. Wang, YJ, Kojetin, D, Burris, TP. Anti-proliferative actions of a synthetic REV-ERBα/β agonist in breast cancer cells. Biochem Pharmacol. 2015;96(4):315-322.
Google Scholar | Crossref | Medline19. Tao, LL, Yu, HY, Liang, R, et al. REV-ERBα inhibits proliferation by reducing glycolytic flux and pentose phosphate pathway in human gastric cancer cells. Oncogenesis. 2019;8(10):1-8.
Google Scholar | Crossref | Medline20. Guillaumond, F, Dardente, H, Giguère, V, Cermakian, N. Differential control of Bmal1 circadian transcription by REV-ERB and ROR nuclear receptors. J Biol Rhythms. 2005;20(5):391-403.
Google Scholar | SAGE Journals | ISI21. Kojetin, DJ, Burris, TP. REV-ERB and ROR nuclear receptors as drug targets. Nat Rev Drug Discov. 2014;13(3):197-216.
Google Scholar | Crossref | Medline22. Popov, VM, Wang, CG, Shirley, LA, et al. The functional significance of nuclear receptor acetylation. Steroids. 2007;72(2):221-230.
Google Scholar | Crossref | Medline | ISI23. Smith, A, Muscat, G. Orphan nuclear receptors: therapeutic opportunities in skeletal muscle. Am J Physiol Cell Physiol. 2006;291(2):203-217.
Google Scholar | Crossref