Abdul, Y., Li, W., Ward, R., Abdelsaid, M., Hafez, S., Dong, G., Jamil, S., Wolf, V., Johnson, M. H., Fagan, S. C., Ergul, A. (2020). Deferoxamine treatment prevents post-stroke vasoregression and neurovascular unit remodeling leading to improved functional outcomes in type 2 male diabetic rats: Role of endothelial ferroptosis. Translational Stroke Research, 12(4), 615–630.
https://doi.org/10.1007/s12975-020-00844-7 Google Scholar |
Crossref |
Medline Adedoyin, O., Boddu, R., Traylor, A., Lever, J. M., Bolisetty, S., George, J. F., Agarwal, A. (2018). Heme oxygenase-1 mitigates ferroptosis in renal proximal tubule cells. American Journal of Physiology Renal Physiology, 314(5), F702–F714.
https://doi.org/10.1152/ajprenal.00044.2017 Google Scholar |
Crossref |
Medline Adibhatla, R. M., Hatcher, J. F., Dempsey, R. J. (2003). Phospholipase A2, hydroxyl radicals, and lipid peroxidation in transient cerebral ischemia. Antioxidants & Redox Signaling, 5(5), 647–654.
https://doi.org/10.1089/152308603770310329 Google Scholar |
Crossref |
Medline |
ISI Aimé, P., Karuppagounder, S. S., Rao, A., Chen, Y., Burke, R. E., Ratan, R. R., Greene, L. A. (2020). The drug adaptaquin blocks ATF4/CHOP-dependent pro-death Trib3 induction and protects in cellular and mouse models of Parkinson’s disease. Neurobiology of Disease, 136, 104725.
https://doi.org/10.1016/j.nbd.2019.104725 Google Scholar |
Crossref |
Medline Alim, I., Caulfield, J. T., Chen, Y., Swarup, V., Geschwind, D. H., Ivanova, E., Seravalli, J., Ai, Y., Sansing, L. H., Ste Marie, E. J., Hondal, R. J., Mukherjee, S., Cave, J. W., Sagdullaev, B. T., Karuppagounder, S. S., Ratan, R. R. (2019). Selenium drives a transcriptional adaptive program to block ferroptosis and treat stroke. Cell, 177(5), 1262–1279.e25.
https://doi.org/10.1016/j.cell.2019.03.032 Google Scholar |
Crossref |
Medline Angeli, J. P. F., Shah, R., Pratt, D. A., Conrad, M. (2017). Ferroptosis inhibition: Mechanisms and opportunities. Trends in Pharmacological Sciences, 38(5), 489–498.
https://doi.org/10.1016/j.tips.2017.02.005 Google Scholar |
Crossref |
Medline Bai, T., Li, M., Liu, Y., Qiao, Z., Wang, Z. (2020). Inhibition of ferroptosis alleviates atherosclerosis through attenuating lipid peroxidation and endothelial dysfunction in mouse aortic endothelial cell. Free Radical Biology & Medicine, 160, 92–102.
https://doi.org/10.1016/j.freeradbiomed.2020.07.026 Google Scholar |
Crossref |
Medline Bannai, S. (1986). Exchange of cystine and glutamate across plasma membrane of human fibroblasts. The Journal of Biological Chemistry, 261(5), 2256–2263.
https://doi.org/10.1016/S0021-9258(17)35926-4 Google Scholar |
Crossref |
Medline Bannai, S., Kitamura, E. (1980). Transport interaction of L-cystine and L-glutamate in human diploid fibroblasts in culture. The Journal of Biological Chemistry, 255(6), 2372–2376.
https://doi.org/10.1016/S0021-9258(19)85901-X Google Scholar |
Crossref |
Medline Bannai, S., Tsukeda, H., Okumura, H. (1977). Effect of antioxidants on cultured human diploid fibroblasts exposed to cystine-free medium. Biochemical and Biophysical Research Communications, 74(4), 1582–1588.
https://doi.org/10.1016/0006-291X(77)90623-4 Google Scholar |
Crossref |
Medline Basso, M., Berlin, J., Xia, L., Sleiman, S. F., Ko, B., Haskew-Layton, R., Kim, E., Antonyak, M. A., Cerione, R. A., Iismaa, S. E., Willis, D., Cho, S., Ratan, R. R. (2012). Transglutaminase inhibition protects against oxidative stress-induced neuronal death downstream of pathological ERK activation. Journal of Neuroscience, 32(19), 6561–6569.
https://doi.org/10.1523/JNEUROSCI.3353-11.2012 Google Scholar |
Crossref |
Medline Bersuker, K., Hendricks, J. M., Li, Z., Magtanong, L., Ford, B., Tang, P. H., Roberts, M. A., Tong, B., Maimone, T. J., Zoncu, R., Bassik, M. C., Nomura, D. K., Dixon, S. J., Olzmann, J. A. (2019). The CoQ oxidoreductase FSP1 acts parallel to GPX4 to inhibit ferroptosis. Nature, 575(7784), 688–692.
https://doi.org/10.1038/s41586-019-1705-2 Google Scholar |
Crossref |
Medline Bogdan, A. R., Miyazawa, M., Hashimoto, K., Tsuji, Y. (2016). Regulators of iron homeostasis: New players in metabolism, cell death, and disease. Trends in Biochemical Sciences, 41(3), 274–286.
https://doi.org/10.1016/j.tibs.2015.11.012 Google Scholar |
Crossref |
Medline Brigelius-Flohé, R., Maiorino, M. (2013). Glutathione peroxidases. Biochimica et Biophysica Acta, 1830(5), 3289–3303.
https://doi.org/10.1016/j.bbagen.2012.11.020 Google Scholar |
Crossref |
Medline Brochier, C., Dennis, G., Rivieccio, M. A., McLaughlin, K., Coppola, G., Ratan, R. R., Langley, B. (2013). Specific acetylation of p53 by HDAC inhibition prevents DNA damage-induced apoptosis in neurons. Journal of Neuroscience, 33(20), 8621–8632.
https://doi.org/10.1523/JNEUROSCI.5214-12.2013 Google Scholar |
Crossref |
Medline Canals, S., Casarejos, M. J., de Bernardo, S., Rodríguez-Martín, E., Mena, M. A. (2003). Nitric oxide triggers the toxicity due to glutathione depletion in midbrain cultures through 12-lipoxygenase. Journal of Biological Chemistry, 278(24), 21542–21549.
https://doi.org/10.1074/jbc.M213174200 Google Scholar |
Crossref |
Medline Cao, J., Chen, X., Jiang, L., Lu, B., Yuan, M., Zhu, D., Zhu, H., He, Q., Yang, B., Ying, M. (2020). DJ-1 suppresses ferroptosis through preserving the activity of S-adenosyl homocysteine hydrolase. Nature Communications, 11(1), 1251.
https://doi.org/10.1038/s41467-020-15109-y Google Scholar |
Crossref |
Medline Cao, Y., Luo, Y., Zou, J., Ouyang, J., Cai, Z., Zeng, X., Ling, H., Zeng, T. (2019). Autophagy and its role in gastric cancer. Clinica Chimica Acta; International Journal of Clinical Chemistry, 489, 10–20.
https://doi.org/10.1016/j.cca.2018.11.028 Google Scholar |
Crossref |
Medline Caso, J. R., Pradillo, J. M., Hurtado, O., Lorenzo, P., Moro, M. A., Lizasoain, I. (2007). Toll-like receptor 4 is involved in brain damage and inflammation after experimental stroke. Circulation, 115(12), 1599–1608.
https://doi.org/10.1161/CIRCULATIONAHA.106.603431 Google Scholar |
Crossref |
Medline Cetin, C., Erdogan, A. M., Dincel, G. C., Bakar, B., Kisa, U. (2017). Effects of sulphasalazine in cerebral ischemia reperfusion injury in rat. Archives of Medical Research, 48(3), 247–256.
https://doi.org/10.1016/j.arcmed.2017.06.004 Google Scholar |
Crossref |
Medline Chamorro, Á., Dirnagl, U., Urra, X., Planas, A. M. (2016). Neuroprotection in acute stroke: Targeting excitotoxicity, oxidative and nitrosative stress, and inflammation. The Lancet Neurology, 15(8), 869–881.
https://doi.org/10.1016/S1474-4422(16)00114-9 Google Scholar |
Crossref |
Medline Chatterjee, S., Zaman, K., Ryu, H., Conforto, A., Ratan, R. R. (2001). Sequence-selective DNA binding drugs mithramycin A and chromomycin A3 are potent inhibitors of neuronal apoptosis induced by oxidative stress and DNA damage in cortical neurons. Annals of Neurology, 49(3), 345–354.
https://doi.org/10.1002/ana.71 Google Scholar |
Crossref |
Medline Chen, L. D., Wu, R. H., Huang, Y. Z., Chen, M. X., Zeng, A. M., Zhuo, G. F., Xu, F. S., Liao, R., Lin, Q. C. (2020). The role of ferroptosis in chronic intermittent hypoxia-induced liver injury in rats. Sleep & Breathing = Schlaf & Atmung, 24(4), 1767–1773.
https://doi.org/10.1007/s11325-020-02091-4 Google Scholar |
Crossref |
Medline Cheng, J., Fan, Y. Q., Liu, B. H., Zhou, H., Wang, J. M., Chen, Q. X. (2020). ACSL4 Suppresses glioma cells proliferation via activating ferroptosis. Oncology Reports, 43(1), 147–158.
https://doi.org/10.3892/or.2019.7419 Google Scholar |
Medline Cheng, N. T., Kim, A. S. (2015). Intravenous thrombolysis for acute ischemic stroke within 3 hours versus between 3 and 4.5 hours of symptom onset. The Neurohospitalist, 5(3), 101–109.
https://doi.org/10.1177/1941874415583116 Google Scholar |
SAGE Journals |
ISI Cheung, P. Y., Wang, W., Schulz, R. (2000). Glutathione protects against myocardial ischemia-reperfusion injury by detoxifying peroxynitrite. Journal of Molecular and Cellular Cardiology, 32(9), 1669–1678.
https://doi.org/10.1006/jmcc.2000.1203 Google Scholar |
Crossref |
Medline Choi, D. W., Maulucci-Gedde, M., Kriegstein, A. R. (1987). Glutamate neurotoxicity in cortical cell culture. The Journal of Neuroscience: The Official Journal of the Society for Neuroscience, 7(2), 357–368.
https://doi.org/10.1523/JNEUROSCI.07-02-00357.1987 Google Scholar |
Crossref |
Medline Cong, L., Dong, X., Wang, Y., Deng, Y., Li, B., Dai, R. (2019). On the role of synthesized hydroxylated chalcones as dual functional amyloid-β aggregation and ferroptosis inhibitors for potential treatment of Alzheimer’s disease. European Journal of Medicinal Chemistry, 166, 11–21.
https://doi.org/10.1016/j.ejmech.2019.01.039 Google Scholar |
Crossref |
Medline Crawford, R. R., Prescott, E. T., Sylvester, C. F., Higdon, A. N., Shan, J., Kilberg, M. S., Mungrue, I. N. (2015). Human CHAC1 protein degrades glutathione, and mRNA induction is regulated by the transcription factors ATF4 and ATF3 and a bipartite ATF/CRE regulatory element. The Journal of Biological Chemistry, 290(25), 15878–15891.
https://doi.org/10.1074/jbc.M114.635144 Google Scholar |
Crossref |
Medline Dang, C. V. (2012). MYC On the path to cancer. Cell, 149(1), 22–35.
https://doi.org/10.1016/j.cell.2012.03.003 Google Scholar |
Crossref |
Medline Dávalos, A., Fernandez-Real, J. M., Ricart, W., Soler, S., Molins, A., Planas, E., Genís, D. (1994). Iron-related damage in acute ischemic stroke. Stroke, 25(8), 1543–1546.
https://doi.org/10.1161/01.STR.25.8.1543 Google Scholar |
Crossref |
Medline Davis, R. J. (1993). The mitogen-activated protein kinase signal transduction pathway. Journal of Biological Chemistry, 268(20), 14553–14556.
https://doi.org/10.1016/S0021-9258(18)82362-6 Google Scholar |
Crossref |
Medline Degterev, A., Huang, Z., Boyce, M., Li, Y., Jagtap, P., Mizushima, N., Cuny, G. D., Mitchison, T. J., Moskowitz, M. A., Yuan, J. (2005). Chemical inhibitor of nonapoptotic cell death with therapeutic potential for ischemic brain injury. Nature Chemical Biology, 1(2), 112–119.
https://doi.org/10.1038/nchembio711 Google Scholar |
Crossref |
Medline |
ISI Dietrich, R. B., Bradley, W. G.. (1988). Iron accumulation in the basal ganglia following severe ischemic-anoxic insults in children. Radiology, 168(1), 203–206.
https://doi.org/10.1148/radiology.168.1.3380958 Google Scholar |
Crossref |
Medline Dixon, S. J. (2017). Ferroptosis: Bug or feature? Immunological Reviews, 277(1), 150–157.
https://doi.org/10.1111/imr.12533 Google Scholar |
Crossref |
Medline Dixon, S. J., Lemberg, K. M., Lamprecht, M. R., Skouta, R., Zaitsev, E. M., Gleason, C. E., Patel, D. N., Bauer, A. J., Cantley, A. M., Yang, W. S., Morrison, B., Stockwell, B. R. (2012). Ferroptosis: An iron-dependent form of nonapoptotic cell death. Cell, 149(5), 1060–1072.
https://doi.org/10.1016/j.cell.2012.03.042 Google Scholar |
Crossref |
Medline Doll, S., Freitas, F. P., Shah, R., Aldrovandi, M., da Silva, M. C., Ingold, I., Grocin, A. G., da Silva, T. N. X., Panzilius, E., Scheel, C. H., Mourão, A., Buday, K., Sato, M., Wanninger, J., Vignane, T., Mohana, V., Rehberg, M., Flatley, A., Schepers, A., … Conrad, M. (2019). FSP1 Is a glutathione-independent ferroptosis suppressor. Nature, 575(7784), 693–698.
https://doi.org/10.1038/s41586-019-1707-0 Google Scholar |
Crossref |
Medline Doll, S., Proneth, B., Tyurina, Y. Y., Panzilius, E., Kobayashi, S., Ingold, I., Irmler, M., Beckers, J., Aichler, M., Walch, A., Prokisch, H., Trümbach, D., Mao, G., Qu, F., Bayir, H., Füllekrug, J., Scheel, C. H., Wurst, W., Schick, J. A., … Conrad, M. (2017). ACSL4 Dictates ferroptosis sensitivity by shaping cellular lipid composition. Nature Chemical Biology, 13(1), 91–98.
https://doi.org/10.1038/nchembio.2239 Google Scholar |
Crossref |
Medline Dolma, S., Lessnick, S. L., Hahn, W. C., Stockwell, B. R. (2003). Identification of genotype-selective antitumor agents using synthetic lethal chemical screening in engineered human tumor cells. Cancer Cell, 3(3), 285–296.
https://doi.org/10.1016/S1535-6108(03)00050-3 Google Scholar |
Crossref |
Medline
留言 (0)