Vitamin D as an Adjuvant Immune Enhancer to SARS-Cov-2 Vaccine

Borsche L, Glauner B, von Mendel J (2021) COVID-19 mortality risk correlates inversely with vitamin D3 status, and a mortality rate close to zero could theoretically be achieved at 50 ng/mL 25(OH)D3: results of a systematic review and meta-analysis. Nutrients 13(10):3596. https://doi.org/10.3390/nu13103596

Article  CAS  PubMed  PubMed Central  Google Scholar 

Sayed AM, Alhadrami HA, El-Gendy AO, Shamikh YI, Belbahri L, Hassan HM, Abdelmohsen UR, Rateb ME (2020) Microbial natural products as potential inhibitors of SARS-CoV-2 main protease (Mpro). Microorganisms 8(7):970. https://doi.org/10.3390/microorganisms8070970

Article  CAS  PubMed  PubMed Central  Google Scholar 

Li Q, Wu J, Nie J, Zhang L, Hao H, Liu S, Zhao C, Zhang Q, Liu H, Nie L, Qin H, Wang M, Lu Q, Li X, Sun Q, Liu J, Zhang L, Li X, Huang W, Wang Y (2020) The impact of mutations in SARS-CoV-2 spike on viral infectivity and antigenicity. Cell 182(5):1284-1294.e9. https://doi.org/10.1016/j.cell.2020.07.012

Article  CAS  PubMed  PubMed Central  Google Scholar 

Hou YJ, Chiba S, Halfmann P, Ehre C, Kuroda M, Dinnon KH 3rd, Leist SR, Schäfer A, Nakajima N, Takahashi K, Lee RE, Mascenik TM, Graham R, Edwards CE, Tse LV, Okuda K, Markmann AJ, Bartelt L, de Silva A, Margolis DM, Boucher RC, Randell SH, Suzuki T, Gralinski LE, Kawaoka Y, Baric RS (2020) SARS-CoV-2 D614G variant exhibits efficient replication ex vivo and transmission in vivo. Science 370(6523):1464–1468. https://doi.org/10.1126/science.abe8499

Article  CAS  PubMed  PubMed Central  Google Scholar 

Korber B, Fischer WM, Gnanakaran S, Yoon H, Theiler J, Abfalterer W, Hengartner N, Giorgi EE, Bhattacharya T, Foley B, Hastie KM, Parker MD, Partridge DG, Evans CM, Freeman TM, de Silva TI, McDanal C, Perez LG, Tang H, Moon-Walker A, Whelan SP, LaBranche CC, Saphire EO, Montefiori DC, Sheffield COVID-19 Genomics Group (2020) Tracking changes in SARS-CoV-2 spike: evidence that D614G increases infectivity of the COVID-19 virus. Cell 182(4):812-827.e19. https://doi.org/10.1016/j.cell.2020.06.043

Article  CAS  PubMed  PubMed Central  Google Scholar 

Brown CM, Vostok J, Johnson H, Burns M, Gharpure R, Sami S, Sabo RT, Hall N, Foreman A, Schubert PL, Gallagher GR, Fink T, Madoff LC, Gabriel SB, MacInnis B, Park DJ, Siddle KJ, Harik V, Arvidson D, Brock-Fisher T, Dunn M, Kearns A, Laney AS (2021) Outbreak of SARS-CoV-2 infections, including COVID-19 vaccine breakthrough infections, associated with large public gatherings - Barnstable County, Massachusetts, July 2021. MMWR Morb Mortal Wkly Rep 70(31):1059–1062. https://doi.org/10.15585/mmwr.mm7031e2

Article  CAS  PubMed  PubMed Central  Google Scholar 

Chiodini I, Gatti D, Soranna D, Merlotti D, Mingiano C, Fassio A, Adami G, Falchetti A, Eller-Vainicher C, Rossini M, Persani L, Zambon A, Gennari L (2021) Vitamin D status and SARS-CoV-2 infection and COVID-19 clinical outcomes. Front Public Health 9:736665. https://doi.org/10.3389/fpubh.2021.736665

Article  PubMed  PubMed Central  Google Scholar 

Shakoor H, Feehan J, Al Dhaheri AS, Ali HI, Platat C, Ismail LC, Apostolopoulos V, Stojanovska L (2021) Immune-boosting role of vitamins D, C, E, zinc, selenium and omega-3 fatty acids: Could they help against COVID-19? Maturitas 143:1–9. https://doi.org/10.1016/j.maturitas.2020.08.003

Article  CAS  PubMed  Google Scholar 

Ghelani D, Alesi S, Mousa A, Vitamin D (2021) and COVID-19: an overview of recent evidence. Int J Mol Sci 22(19):10559. https://doi.org/10.3390/ijms221910559

Article  CAS  PubMed  PubMed Central  Google Scholar 

Bui L, Zhu Z, Hawkins S, Cortez-Resendiz A, Bellon A (2021) Vitamin D regulation of the immune system and its implications for COVID-19: a mini review. SAGE Open Med 9:20503121211014070. https://doi.org/10.1177/20503121211014073

Article  PubMed  PubMed Central  Google Scholar 

Amrein K, Scherkl M, Hoffmann M, Neuwersch-Sommeregger S, Köstenberger M, Tmava Berisha A, Martucci G, Pilz S, Malle O (2020) Vitamin D deficiency 2.0: an update on the current status worldwide. Eur J Clin Nutr 74(11):1498–1513. https://doi.org/10.1038/s41430-020-0558-y

Article  CAS  PubMed  PubMed Central  Google Scholar 

Holick MF, Binkley NC, Bischoff-Ferrari HA, Gordon CM, Hanley DA, Heaney RP, Murad MH, Weaver CM, Endocrine Society (2011) Evaluation, treatment, and prevention of vitamin D deficiency: an endocrine society clinical practice guideline. J Clin Endocrinol Metab 96(7):1911–1930 https://doi.org/10.1210/jc.2011-0385. Erratum in: J Clin Endocrinol Metab. 2011;96(12):3908. Erratum in: J Clin Endocrinol Metab. 2024:dgae373. https://doi.org/10.1210/clinem/dgae373

Mariani J, Antonietti L, Tajer C, Ferder L, Inserra F, Sanchez Cunto M, Brosio D, Ross F, Zylberman M, López DE, Luna Hisano C, Maristany Batisda S, Pace G, Salvatore A, Hogrefe JF, Turela M, Gaido A, Rodera B, Banega E, Iglesias ME, Rzepeski M, Gomez Portillo JM, Bertelli M, Vilela A, Heffner L, Annetta VL, Moracho L, Carmona M, Melito G, Martínez MJ, Luna G, Vensentini N, Manucha W (2022) High-dose vitamin D versus placebo to prevent complications in COVID-19 patients: multicentre randomized controlled clinical trial. PLoS ONE 17(5):e0267918. https://doi.org/10.1371/journal.pone.0267918

Article  CAS  PubMed  PubMed Central  Google Scholar 

Grant WB, Lahore H, McDonnell SL, Baggerly CA, French CB, Aliano JL, Bhattoa HP (2020) Evidence that Vitamin D supplementation could reduce risk of influenza and COVID-19 infections and deaths. Nutrients 12(4):988. https://doi.org/10.3390/nu12040988

Article  CAS  PubMed  PubMed Central  Google Scholar 

Holick MF (2009) Vitamin D status: measurement, interpretation, and clinical application. Ann Epidemiol 19(2):73–78. https://doi.org/10.1016/j.annepidem.2007.12.001

Article  PubMed  Google Scholar 

Melamed ML, Michos ED, Post W, Astor B (2008) 25-hydroxyvitamin D levels and the risk of mortality in the general population. Arch Intern Med 168(15):1629–1637. https://doi.org/10.1001/archinte.168.15.1629

Article  PubMed  PubMed Central  Google Scholar 

Scragg R, Sowers M, Bell C, Third National Health and Nutrition Examination Survey (2004) Serum 25-hydroxyvitamin D, diabetes, and ethnicity in the third national health and nutrition examination survey. Diabetes Care 27(12):2813–2818. https://doi.org/10.2337/diacare.27.12.2813

Article  CAS  PubMed  Google Scholar 

Lalor MK, Floyd S, Gorak-Stolinska P, Weir RE, Blitz R, Branson K, Fine PE, Dockrell HM (2011) BCG vaccination: a role for vitamin D? PLoS ONE 6(1):e16709. https://doi.org/10.1371/journal.pone.0016709

Article  CAS  PubMed  PubMed Central  Google Scholar 

Greiller CL, Martineau AR (2015) Modulation of the immune response to respiratory viruses by vitamin D. Nutrients 7(6):4240–4270. https://doi.org/10.3390/nu7064240

Article  CAS  PubMed  PubMed Central  Google Scholar 

Santaolalla A, Beckmann K, Kibaru J, Josephs D, Van Hemelrijck M, Irshad S (2020) Association between Vitamin D and Novel SARS-CoV-2 respiratory dysfunction-a scoping review of current evidence and its implication for COVID-19 pandemic. Front Physiol 11:564387. https://doi.org/10.3389/fphys.2020.564387

Article  PubMed  PubMed Central  Google Scholar 

Mariani J, Giménez VMM, Bergam I, Tajer C, Antonietti L, Inserra F, Ferder L, Manucha W (2021) Association between Vitamin D deficiency and COVID-19 incidence, complications, and mortality in 46 countries: an ecological study. Health Secur 19(3):302–308. https://doi.org/10.1089/hs.2020.0137

Article  PubMed  Google Scholar 

Petrelli F, Luciani A, Perego G, Dognini G, Colombelli PL, Ghidini A (2021) Therapeutic and prognostic role of vitamin D for COVID-19 infection: a systematic review and meta-analysis of 43 observational studies. J Steroid Biochem Mol Biol 211:105883. https://doi.org/10.1016/j.jsbmb.2021.105883

Article  CAS  PubMed  PubMed Central  Google Scholar 

Panagiotou G, Tee SA, Ihsan Y, Athar W, Marchitelli G, Kelly D, Boot CS, Stock N, Macfarlane J, Martineau AR, Burns G, Quinton R (2020) Low serum 25-hydroxyvitamin D (25[OH]D) levels in patients hospitalized with COVID-19 are associated with greater disease severity. Clin Endocrinol (Oxf) 93(4):508–511. https://doi.org/10.1111/cen.14276.doi10.1111/cen.14276

Article  CAS  PubMed  Google Scholar 

Chowdhury MA, Hossain N, Kashem MA, Shahid MA, Alam A (2020) Immune response in COVID-19: a review. J Infect Public Health 13(11):1619–1629. https://doi.org/10.1016/j.jiph.2020.07.001

Article  PubMed  PubMed Central  Google Scholar 

Abebe EC, Dejenie TA (2023) Protective roles and protective mechanisms of neutralizing antibodies against SARS-CoV-2 infection and their potential clinical implications. Front Immunol 14:1055457. https://doi.org/10.3389/fimmu.2023.1055457

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